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What The Study Did: This study combined the results of 15 observational studies with 9,500 patients who underwent radical hysterectomy for early-stage cervical cancer to compare the risk of cancer recurrence and death associated with receiving minimally invasive versus open radical hysterectomy.
Authors: Alexander Melamed, M.D., M.P.H., of the Columbia University Vagelos College of Physicians and Surgeons in New York, is the corresponding author.
An international research team has been stunned to discover that some species of ancient crocodiles walked on their two hind legs like dinosaurs and measured over three metres in length.
University of Queensland palaeontologist Dr Anthony Romilio said the researchers first thought the similar-shaped fossilised footprints were from another ancient animal known as the pterosaurs.
"At one site, the footprints were initially thought to be made by a giant bipedal pterosaur walking on the mudflat, we now understand that these were bipedal crocodile prints," Dr Romilio said.
What The Study Did: The association between climate and the spread of COVID-19 is examined in this observational study.
Authors: Mohammad M. Sajadi, M.D., of the University of Maryland School of Medicine in Baltimore, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2020.11834)
What The Study Did: How commonly reported gastrointestinal symptoms were in patients with COVID-19 and viral RNA shedding was detected in these patients' stool are examined in this systematic review and meta-analysis.
Authors: Sravanthi Parasa, M.D., of Swedish Medical Center in Seattle, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2020.11335)
A new study released today in Scientific Reports announced the surprising discovery of abundant, well-preserved 110-120-million-year-old footprints, belonging to a large bipedal ancestor of modern-day crocodiles from the Lower Cretaceous Jinju Formation of South Korea. The team of palaeontologist trackers that made the discovery includes researchers from Korea, Australia, and University of Colorado Denver professor, Martin Lockley.
We move our eyes several times per second. These fast eye movements, called saccades, create large image shifts on the retina - making our visual system work hard to maintain a stable perceptual world. Remapping the retinal image compensates for this; however, errors in actual eye movements cause image shifts, even with remapping.
Leesburg, VA, June 11, 2020--An open-access article published in the American Journal of Roentgenology (AJR) by radiologists in Singapore recommends a number of applied updates to the workflow of diagnostic ultrasound (US) to prevent nosocomial transmission of coronavirus disease (COVID-19) to frontline US service providers, who could inadvertently become vectors for onward transmission.
Aquatic internet that sends data through light beams could enable divers to instantly transmit footage from under the sea to the surface.
The internet is an indispensable communication tool, connecting tens of billions of devices worldwide, and yet we struggle to connect to the web from under water. "People from both academia and industry want to monitor and explore underwater environments in detail," explains the first author, Basem Shihada. Wireless internet under the sea would enable divers to talk without hand signals and send live data to the surface.
Highlights:
In 2018 scientists from Gladyshev lab specializing in aging research started a collaboration with Insilico Medicine resulting in a widely-publicized proof of concept microbiomic aging clock ;
The clock has been validated on multiple independent data sets;
The clock was shown to be biologically-relevant and used to demonstrate that diabetic patients look older than their chronological age;
The study was published in iScience and is expected to be used in new data analysis tools for COVID-19 and longevity research;
Improving the prediction of survival indicators in patients with breast cancer using tools from artificial intelligence and probabilistic modelling is the aim of ModGraProDep, an innovative system presented in a study led by Ramon Clèries, lecturer at the Department of Clinical Sciences of the Faculty of Medicine and Health Sciences of the University of Barcelona and member of the Oncology Master Plan/ICO-IDIBELL. The study has been published in the journal Artificial Intelligence in Medicine.
Newly discovered creatures can often be as impressive and exciting as the ones from the Japanese movies and shows. Many of those fictional characters, including inhabitants of the famous Pokémon universe, might have their analogues among the real animals native to Japan.
Japan -- Every second of every day, countless biochemical reactions take place in our bodies' cells. The organization of this complex system is the result of billions of years of evolution, fine-tuning our functions since the first primordial organisms.
One such vital reaction is 'methylation', where a methyl group -- a carbon atom linked to three hydrogen atoms -- attaches itself to a target molecule. Methylation is involved in the regulation of everything from DNA to proteins, and it is so vital that it can be found in all living organisms.
When an embryo develops, a wide variety of proteins and enzymes trigger a series of biochemical reactions. The development of the lymphatic vasculature is crucially dependent on one specific protein - the growth factor VEGF-C. In order to become biologically active and to initiate downstream signalling events, the protein must first undergo processing steps. Thus far it was unclear, however, how and where the necessary factors come together that are required for VEGF-C activation, and which cell types provide these individual factors during development.
An article published in the advanced online edition of the journal Computer Communications shows that the use of machine learning can improve the operation and performance of the Wi-Fi networks of the future, those of the 5G/6G ecosystem. The research was conducted by Marc Carrascosa and Boris Bellalta, researchers with the Wireless Networking Research Group at the UPF Department of Information and Communication Technologies (DTIC).
'DNA makes RNA makes protein' is a fundamental principle in molecular biology. The process of gene expression, namely creating RNA from a specific DNA sequence, is tightly regulated in different ways. The DNA itself carries a reversible chemical modification - called methylation - that can influence gene expression.