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Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer's disease, but also reverse the effects of the disorders.
The team, based at Tohoku University, published their results on June 8 in the International Journal of Molecular Sciences. The treatment candidate has been declared safe by Japan's governing board, and the researchers plan to begin clinical trials in humans in the next year.
Bobtail and bottletail squids are tiny marine invertebrates that are found throughout the world's oceans and are useful model animals for research
There are 68 recognized species of bobtail squid and five recognized species of bottletail squid, but the timing of their divergence from one another is still relatively unknown
Researchers at OIST, Hiroshima University and the National University of Ireland Galway, collected 32 species of bobtail and bottletail squids
Attention Deficit Hyperactivity Disorder (ADHD) affects about 7% of children, with a two out of three chance of persisting into adulthood. This neurodevelopmental disorder is characterised by concentration difficulties, increased distractibility, impulsivity and hyperactivity. Today, ADHD is treated with pharmaceutical drugs that may have unwanted side effects.
An international team of researchers has identified a novel mechanism in barley plants, which could help crop growers achieve high yields as temperatures rise.
With grain production highly sensitive to changing environmental conditions, rising temperatures are known to reduce the number of seeds that can be produced on each plant. One solution is to increase the number of flowers or branches on each 'spike', which is the reproductive structure from which grain is harvested.
Earthworms experience constant chemical interactions with bacteria, fungi, plants and small invertebrates across soil ecosystems. Even within their tissues, earthworms harbor symbiotic microbes and small animal parasites that trigger internal metabolic responses such as innate immunity. To reveal the fundamental processes that enable animal-microbe symbioses to form and persist, we have to study their metabolic interactions in situ.
Russian scientists have experimentally proved the existence of a new type of quasiparticle - previously unknown excitations of coupled pairs of photons in qubit chains. This discovery could be a step towards disorder-robust quantum metamaterials. The study was published in Physical Review B.
A stimulating environment keeps the "hippocampus" - which is the brain's memory control center - young, so to speak. Causes of this are molecular mechanisms that affect gene regulation. These current findings from studies in mice provide clues as to why an active, varied life can help preserve mental fitness in old age. Researchers from the DZNE and the Center for Regenerative Therapies Dresden (CRTD) at the Technische Universität Dresden report on this in the journal Nature Communications.
A new technique established by a team of researchers from the University of Cambridge and the University of Massachusetts reveals the fundamental physics of how a polymer such as DNA threads through holes 10,000 times smaller than the width of a human hair.
Polymers are long, chain-like molecules which are everywhere in biology. DNA and RNA are polymers formed by many consecutive copies of nucleotides coupled together. When being transported within or between cells, these biological polymers must pass through nanometre-sized holes called "nanopores".
Researchers at the University of Leicester have developed a new method to recycle electric vehicle batteries using a ground-breaking new approach that many will have experienced in the dentist's chair.
The Faraday Institution project on the recycling of lithium-ion batteries (ReLiB) led by Professor Andy Abbott at the University of Leicester used a new method, involving ultrasonic waves, to solve a critical challenge: how to separate out valuable materials from electrodes so that the materials can be fully recovered from batteries at the end of their life.
Mineral resources from Chile are of great importance to Germany. According to statistics from the World Bank, thousands of tons of valuable minerals are imported from the South American country every year, including raw materials for lithium-ion batteries. But their extraction causes ecological and social problems: "The use of the limited freshwater resources in northern Chile for mining regularly fuels conflicts with the local population," says Professor Thomas Kohl from KIT's Institute of Applied Geosciences (AGW).
When positioned strategically, garment seams sewn with conductive yarn can be used to accurately track body motion, according to computer scientists at the University of Bath in the UK. Best of all, these charged seams are able to respond to subtle movements that aren't picked up by popular fitness trackers, such as watches and wristbands.
In a new study, the Bath researchers found that clothing made with conductive seams can be analysed to identify the wearer's movements.
Mice are an important animal model of human vision due to the powerful genetic tools available in this species. However, mouse vision was thought to be different to that of humans because humans have a region of the retina specialized for fine details called the 'fovea' whereas mice do not. Researchers from the Netherlands Institute of Neuroscience (NIN) have shown that the visual cortex of mice does contain a region of enhanced visual sensitivity dubbed the 'focea', making the mouse a better model of human vision than previously expected.
Lithia, Florida -- June 29, 2021 -- Surgical resident training has traditionally occurred in a master-apprentice-type relationship, with graduated responsibilities until trainees are expected to perform procedures on their own. Given recent changes in the health care system, including reduced operating room time, increased difficulty of procedures and working hour restrictions, there is less time for residents to learn using traditional methods.
Aerosol generated by playing woodwind and brass instruments is less than that produced when vocalising (speaking and singing) and is no different than a person breathing, new research has found. The findings, published online in the journal Aerosol Science and Technology, could be crucial to developing a roadmap for lifting COVID-19 restrictions in the performing arts, which have been significantly restricted since the start of the pandemic.
The death of neurons specialised in the synthesis of dopamine, one of the brain's main neurotransmissors, deteriorates the motor and cognitive capacities of those with Parkinson's disease. The loss of these neurons is related to alpha-synuclein aggregation. Recent studies show that oligomers, the initial aggregates of this protein, are the most pathogenic forms of α-synuclein and are responsible for the spreading of the disease in the brain.