Culture
Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown. In a study conducted by a research group led by Peter Wolf, Martin Krssak and Michael Krebs from MedUni Vienna's Department of Medicine III, magnetic resonance spectroscopy (MRS) was used to show that there is a direct correlation between the elimination of glucose via the kidneys and new glucose production in the liver.
Researchers at the Kobe University Graduate School of Science have revealed that when captive-bred juvenile red-spotted masu salmon are released into natural streams, very few individuals become migrants.
Red-spotted masu salmon was an important fish species for the fishing industry in the rivers of west Japan, however in recent years their numbers are declining rapidly. The results of this research offer important suggestions for stocking practices and the management of river environments.
A study reveals the genetic factors that may expose or protect people with Down syndrome from SARS-CoV-2 infection, as well as the prognosis of COVID-19.
Their findings, which are published in the journal Scientific Reports, follow previous studies showing a tenfold mortality risk of COVID-19 for people with Down syndrome, adding further evidence to boost existing calls for priority vaccination of the medically vulnerable group.
In humans, differences in personalities have been evident since the ancient times. Personality in animals has long been ignored, but recently this question has received increasing research interest as it has been realized that personality has evolutionary and ecological significance. An international team of behavioral biologists from Austria, Brazil and the Netherlands, with Vedrana Å lipogor from the University of Vienna as leading author of the study, designed a set of tasks to assess personality of common marmosets.
Researchers from the Institute of Environmental Science and Technology of the Universitat Autònoma de Barcelona (ICTA-UAB) warn of the impact the current tourism model in the Mediterranean islands has on the production of marine litter on beaches, and recommend taking advantage of the situation generated by the Covid19 pandemic to rethink a new more sustainable model.
A German-Chinese research team has found a new synthetic route to produce biofuel from biomass. The chemists converted the substance 5-hydroxymethylfurfural (HMF) produced from biomass into 2,5-dimethylfuran (DMF), which could be suitable as a biofuel. Compared to previous methods, they achieved a higher yield and selectivity under milder reaction conditions. The team led by Dr.
The molecular details of how SARS-CoV-2 enters cells and infects them are still not clear. Researchers at Uppsala University have tested the bioinformatic predictions made by another research group and have identified receptors that could be important players in the process. The results are presented in the journal Science Signaling and at the AAAS Annual Meeting held this week.
Femtosecond direct laser writing as a 3D printing technology has been one of the key building blocks for miniaturization in modern times. It has transformed the field of complex microoptics since the early 2000s. Especially medical engineering and consumer electronics as vastly growing fields benefit from these developments. It is now possible to create robust, monolithic and nearly perfectly aligned freeform optical systems on almost arbitrary substrates such as image sensors or optical fibers.
In diagnostic medicine, biopsies, where a sample of tissue is extracted for analysis, is a common tool for the detection of many conditions. But this approach has several drawbacks - it can be painful, doesn't always extract the diseased tissue, and can only be used in a sufficiently advanced disease stage, making it, in some cases, too late for intervention. These concerns have encouraged researchers to find less invasive and more accurate options for diagnoses.
A study has described genetic changes in patients with the most common form of hereditary kidney disease that affects an estimated 12.5 million people worldwide. The research, which focussed on Polycystic Kidney Disease (PKD) in Ireland, provides insights into PKD that will assist doctors and patients in the management of this of inherited condition.
The study, led by researchers from the RCSI University of Medicine and Health Sciences, is published in the European Journal of Human Genetics.
Results from a new study which draws on survey data collected during the peak of the first wave of the pandemic suggests that being forced to slow down life, as a consequence of lockdown, has had significant, positive impacts for many people and their families.
Cells, like humans, cast votes to make decisions as a group. But how do they know what to vote for? Researchers at the Francis Crick Institute and King's College London have uncovered how cells actively seek information in order to make faster and better collective decisions to coordinate the growth of new blood vessels. This provides a new basis for understanding intelligence in cells.
Goal 7 of the Sustainable Development Goals (SDGs) aims to ensure access to affordable, reliable, sustainable and modern energy for all by 2030. Yet according to new research by Copenhagen Business School the poor planning and execution of decarbonisation strategies in emerging markets challenges the aims of Goal 7.
BUFFALO, N.Y. -- In cells, numerous important biochemical functions take place within spherical chambers made from proteins and RNA.
These compartments are akin to specialized rooms inside a house, but their architecture is radically different: They don't have walls. Instead, they take the form of liquid droplets that don't have a membrane, forming spontaneously, similar to oil droplets in water. Sometimes, the droplets are found alone. Other times, one droplet can be found nested inside of another. And these varying assemblies can regulate the functions the droplets perform.
Some coronaviruses can add to their genetic pool some genes belonging to the host they infected. In this way, they can blend in and be less detectable to the immune system. This discovery was published in the journal Viruses by an Italian research team from the IIS (Italian Healthcare Institute), ISPRA (Institute for Environmental Protection and Research), IZSLER (Italian health authority and research organization for animal health and food safety of Lombardy and Emilia-Romagna) and the University of Bologna.