Culture

Periodic pulses of light forming a comb in the frequency domain are
widely used for sensing and ranging. The key to the miniaturisation of
this technology towards chip-integrated solutions is the generation of
dissipative solitons in ring-shaped microresonators. Dissipative solitons
are stable pulses circulating around the circumference of a nonlinear
resonator.

Cancer researcher Rita Fior uses zebrafish to study human cancer. Though this may seem like an unlikely match, her work shows great promise with forthcoming applications in personalised medicine.

The basic principle of Fior's approach relies on transplanting human cancer cells into dozens of zebrafish larvae. The fish then serve as "living test tubes" where various treatments, such as different chemotherapy drugs, can be tested to reveal which works best. The assay is rapid, producing an answer within four short days.

University of Warwick scientists model movements of nearly 300 protein structures in Covid-19

Scientists can use the simulations to identify potential targets to test with existing drugs, and even check effectiveness with future Covid variants

Simulation of virus spike protein, part of the virus's 'corona', shows promising mechanism that could potentially be blocked

Genetic mutations which occur naturally during the earliest stages of an embryo's development can cause the severe birth defect spina bifida, finds a new experimental study in mice led by UCL scientists.

The research, published in Nature Communications, explains for the first time how a 'mosaic mutation' - a mutation which is not inherited from either parent (either via sperm or egg cell) but occurs randomly during cell divisions in the developing embryo - causes spina bifida.

What The Study Did: This is a diagnostic study that examines the accuracy and acceptability of a 3-dimensionally printed swab for identifying SARS-CoV-2.

Authors: David M. Allen, M.D., of the National University of Singapore, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaoto.2020.5680)

Peer-reviewed | Observational | People

Study based on 26.5 million Medicare records finds significant racial and ethnic disparities in uptake of seasonal flu vaccine in people living in the USA aged 65 years and older during the 2015-2016 flu season.

Inequities persist among those who were vaccinated, with racial and ethnic minority groups 26-32% less likely to receive the High Dose Vaccine, which is more effective in older people, compared with white older adults.

A new study published in Scientific Reports revealed that dogs understand the relationship between their body and the environment in a problem solving task. The researchers of the Department of Ethology at Eötvös Loránd University (Budapest, Hungary) found that dogs can recognise their body as an obstacle, which ability is one of the basic manifestations of self-representation in humans.

Boys who regularly play video games at age 11 are less likely to develop depressive symptoms three years later, finds a new study led by a UCL researcher.

The study, published in Psychological Medicine, also found that girls who spend more time on social media appear to develop more depressive symptoms.

Taken together, the findings demonstrate how different types of screen time can positively or negatively influence young people's mental health, and may also impact boys and girls differently.

Scientists at EMBL Heidelberg and at the Zentrum für Infektiologie at Heidelberg University Hospital have succeeded for the first time in imaging HIV during transport into the nucleus of an infected cell. The electron tomographic images show the protein envelope of the virus passing through one of the nuclear pores - the openings in the membrane around the nucleus that allow molecules in and out. The scientists found that the virus passes through the nuclear pore intact, only breaking apart inside the nucleus, where it releases its genetic information.

One of the most intriguing features in all living beings is the "biological clock", an internal time-keeping mechanism that governs our behavioral pattern (such as the sleep-wake cycle). In fact, the biological clock dictates the developmental timing of various processes, such as when flowers bloom and insects reproduce. Biologists refer to these activities collectively as "circadian rhythms," owing to the rhythmic pattern in which they occur.

When women undergo surgical treatment for breast cancer, they often also have reconstructive surgery but new QUT research reveals many women feel left out of the decision making.

Quantum computers promise not only to outperform classical machines in certain important tasks, but also to maintain the privacy of data processing. The secure delegation of computations has been an increasingly important issue since the possibility of utilizing cloud computing and cloud networks. Of particular interest is the ability to exploit quantum technology that allows for unconditional security, meaning that no assumptions about the computational power of a potential adversary need to be made.

The imposition of various local and national restrictions in England during the summer and autumn of 2020 gradually reduced contacts between people, but these changes were smaller and more varied than during the lockdown in March, according to a study published in the open access journal BMC Medicine.

After describing a unique behaviour in the Small-banded Kukri Snake (Oligodon fasciolatus) last September, two new studies, also led by Henrik Bringsøe, are now reporting the same gruesome feeding strategy in another two species: the Taiwanese Kukri Snake (Oligodon formosanus) and the Ocellated Kukri Snake (Oligodon ocellatus).

The temporary breakdown of Earth's magnetic field 42,000 years ago sparked major climate shifts that led to global environmental change and mass extinctions, a new international study co-led by UNSW Sydney and the South Australian Museum shows.

This dramatic turning point in Earth's history - laced with electrical storms, widespread auroras, and cosmic radiation - was triggered by the reversal of Earth's magnetic poles and changing solar winds.