A team led by Massachusetts General Hospital (MGH) researchers has developed an innovative way to culture liver cells for drug toxicity screening. In a report in Proceedings of the National Academy of Sciences, the investigators describe how liver cells grown in a high-oxygen environment and in a culture medium free of animal-derived serum quickly begin to function as they do within the liver.
Culture
A new study finds a 2003 reform of the length of resident on-duty hours has led to an increase in the rate of perioperative (the span of all three phases of surgery: before, during and after) complications for patients treated for hip fractures. Among other restrictions, this reform limited the resident workweek to 80 hours. The resulting complications vary significantly, with an increasing rate of worse outcomes seen in teaching hospitals, according to a study published in the Journal of Bone and Joint Surgery (JBJS).
Berlin, 2 September 2009 - Investing in restoration and maintenance of the Earth's multi-trillion dollar ecosystems - from forests and mangroves to wetlands and river basins - can have a key role in countering climate change and climate-proofing vulnerable economies.
Infections caught in hospital are costing the Australian healthcare system more than 850,000 lost bed days, according to a new study by Queensland University of Technology.
Associate Professor Nick Graves, from QUT's Institute of Health and Biomedical Innovation, said there were 175,153 cases where patients had acquired an infection during their hospital stay.
"If rates were reduced by just one per cent, then 150,158 bed days would be released for alternative uses, allowing an estimated 38,500 additional admissions annually," he said.
Atlanta, GA—September 2-3, 2009 – Dr. Jan Nowak, President of the Association for Molecular Pathology presented public comments today at the Clinical Laboratory Improvement Advisory Committee meeting. During the initial weeks of the pandemic H1N1 influenza outbreak, community based molecular pathology laboratories developed diagnostic tests capable of rapidly detecting and confirming suspected cases of pandemic flu. Dr.
A study from the Massachusetts General Hospital (MGH) Institute for Health Policy gives the first detailed look at the types of research currently being conducted within U.S. academic medical centers – medical schools and their affiliated hospitals. The report in the Sept. 2 Journal of the American Medical Association describes how the traditional way of categorizing life-science researchers as either basic or applied clinical investigators does not adequately reflect the reality of today's academic medical research.
- Cheap drinks can lead to higher intoxication levels and a host of related health and safety problems.
- A new study has examined the relationship between alcohol prices at college bars and intoxication upon exit.
- Findings show that, contrary to bar claims, students will purchase more expensive alcoholic drinks and when they do, become less intoxicated than those who purchase more drinks at cheaper prices.
Among patients with Bell Palsy, a facial paralysis with unknown cause, treatment with corticosteroids is associated with a reduced risk of an unsatisfactory recovery, and treatment with a combination of corticosteroids and antiviral agents may be associated with additional benefit, according to a systematic review and meta-analysis of previously published studies, reported in the September 2 issue of JAMA.
A survey indicates that research is active and diverse at U.S. academic medical centers and that a substantial proportion of faculty conduct research and publish without sponsorship, according to a study in the September 2 issue of JAMA.
Washington, DC – While medicine tends to focus on patients as a "collection of visceral organs and a nervous system," systems medicine provides a new approach to medical practice that is "anticipated to result in more comprehensive and systematic patient care", says a commentary published today in the Journal of the American Medical Association. Howard J. Federoff, MD, PhD, executive vice president for health sciences and executive dean of the School of Medicine at Georgetown University Medical Center, and Lawrence O.
Patients who have after-hour orthopaedic surgeries risk a slightly higher rate of necessary follow-up surgeries, according to a study published in the September 2009 issue of The Journal of Bone and Joint Surgery (JBJS). The data also suggests that patients whose surgeries took place during the day have the same healing, recovery time, and major complication rates as patients who have surgery after hours.
Veterinarians from the Wildlife Conservation Society's Bronx Zoo and the University of Tennessee have found a solution to the challenge of providing effective pain relief to some of their most difficult patients: big cats.
The answer: A surgically implanted, capsule-sized pump that provides continuous pain relief while the animal recovers from surgery, according to a new study appearing in the American Journal of Veterinary Research.
COLUMBIA, Mo. – According to the National Center for Chronic Disease Prevention and Health Promotion, 46 million Americans have arthritis. Many of these people take over-the-counter anti-inflammatory medications that block production of certain molecules, known as bioactive lipids, to reduce pain and swelling. Yet, the role of these lipids is not yet understood completely, and medications may have adverse side effects.
According to George Mason University Professor Nicole Darnall, companies don't green their production processes because there are unclear and mixed messages about how doing so will benefit them and their bottom line.
"Many companies want to 'do the right thing' and undertake green production in some form, however they don't know how or lack a compelling reason to do so," says Darnall, an associate professor of corporate sustainability and public policy.
KANSAS CITY, MO — September 1, 2009 — New research on treating Gulf War Illness (GWI) is being presented this week at the Military Health Research Forum (MHRF), a scientific meeting hosted by the Department of Defense (DoD) Congressionally Directed Medical Research Programs (CDMRP). GWI is a condition that affects approximately 25 percent of service men and women who served in the 1990-1991 Gulf War.