Identifying a suitable donor for leukemia and lymphoma patients who need bone marrow transplants may be far easier now that results of two clinical trials show transplant results with half-matched bone marrow or umbilical cord blood are comparable to fully matched tissue, thanks in large part to the availability of effective antirejection drugs and special post-transplant chemotherapy. The finding means that nearly all patients in need of a transplant can find donors, according to Johns Hopkins scientists who participated in the trials.
Culture
NEW YORK, NY (July 6, 2011) - A new study has found that most patients undergoing biopsy of the small intestine do not have the recommended number of samples to diagnose celiac disease. The study, published in the July 2011 issue of Gastrointestinal Endoscopy, analyzed a national database of biopsy specimens maintained by Caris Life Sciences (Irving, TX). More than 100,000 patients had a biopsy of the small intestine, but only 35 percent of them had at least four samples taken, the number recommended by professional guidelines.
SAN DIEGO, CA – Gender may be associated with an increased risk of cartilage lesions in anterior cruciate ligament (ACL) injured knees, according to research being presented at the American Orthopaedic Society for Sports Medicine's Annual Meeting in San Diego.
SAN DIEGO, CA – A smaller sized hamstring graft in an anterior cruciate ligament (ACL) reconstruction patient less than 20 years old may increase revision rates, according to research presented at the American Orthopaedic Society for Sports Medicine's Annual Meeting in San Diego today.
Boston, MA -- Researchers from Harvard School of Public Health (HSPH), Massachusetts Institute of Technology (MIT), the National Bureau of Economic Research (NBER), and Providence Health & Services have found that expanding low income adults' access to Medicaid substantially increases health care use, reduces financial strain on covered individuals, and improves their self-reported health and well-being. This is the first study to evaluate the impact of insuring the uninsured in the U.S. using a randomized controlled trial, the gold standard in medical and scientific studies.
CHICAGO (July 6, 2011) – The type of primary insurance patients carry affects outcomes of cardiac valve operations in the United States according to a study in the May issue of the Journal of the American College of Surgeons. As a result, the type of primary insurance should be considered as an independent risk factor during preoperative risk stratification and planning, the researchers reported. They found that uninsured and Medicaid patients incur worse unadjusted and risk-adjusted outcomes following cardiac valve operations compared with those who carry private insurance.
CHICAGO (July 6, 2011) – One consequence of the expanded access to health care facilitated by health care reform will be a shortfall in the necessary numbers of physicians and other advanced medical professionals. According to a study published in the June issue of the Journal of the American College of Surgeons, the United States will face serious shortages in the combined workforce of physicians, advance practice nurses, and physician assistants over the next two decades. The study concluded that, without an adequate supply of advanced medical professionals, the U.S.
Move over, boy bands of America—there's a new group in town. Four middle-school students from Carmel Valley Middle School in San Diego, California, entered The Christopher Columbus Awards Competition, a science, technology, engineering, and math (STEM) program that challenges middle-school students to identify a community problem and solve it using science and technology. Taking a cue from the popular group the Backstreet Boys, the students call themselves the Back Straight Boys.
Researchers at King's College London have found a molecule in the body which controls sensitivity to pain from UVB irradiation, identifying it as a new target for medicines to treat pain caused by other common inflammatory conditions such as arthritis.
The molecule, called CXCL5, is part of a family of proteins called chemokines, which recruit inflammatory immune cells to the injured tissue, triggering pain and tenderness. This is the first study to reveal this molecule's role in mediating pain.
ROSEMONT, Ill.–While falls are a common cause of injury, particularly in older, hospitalized patients, some may not be as preventable as once thought. According to a new literature review published in the Journal of the American Academy of Orthopaedic Surgeons (JAAOS), many of the risks that frequently cause falls are not adequately addressed with the fall prevention initiatives used in healthcare facilities.
A significant discovery by University of Adelaide researchers shows that the loss of a twin during early pregnancy explains the increased risk of birth defects in multiple IVF pregnancies.
The annual meeting of the European Society of Human Reproduction and Embryology in Stockholm today will hear Associate Professor Michael Davies explain how the "vanishing twin" phenomenon is linked to a nearly two-fold increased risk of congenital malformation in the surviving baby, and a threefold increase in multiple birth defects.
Cultural, ethnic and gender stereotypes can significantly distort clinical judgments about "facially masked" patients with Parkinson's disease, according to a newly published study from researchers at Tufts University, Brandeis University and the National Cheng Kung University in Taiwan.
This can lead to inappropriate and inequitable health care for those suffering from Parkinson's, a common nervous system disorder, particularly in the elderly, with some 50,000 new cases reported in the U.S. each year.
More needs to be done to improve the care that older adults with cognitive impairment - including dementia and delirium - receive when they visit hospital emergency departments, according to a research review in the July issue of the Journal of Advanced Nursing.
Researchers from the University of Alberta reviewed 15 studies published between 1994 and 2009, covering 4,431 patients from the USA, Canada, Australia, Italy, New Zealand and Israel.
POF is not only associated with infertility but also with significantly increased morbidity and mortality, as well as a decreased quality of life equivalent to that of people with type 2 diabetes or rheumatoid arthritis, said Dr. Rumana Islam, from Imperial College, London, UK.
The group looked at 60,650 singletons in a common Nordic database from ART registers in Denmark, Finland, Norway and Sweden and compared these to a control group of 360,022 naturally conceived (NC) singletons. In both groups 0.4 % of singletons were stillborn, with a definition of stillbirth as a dead child after 22 weeks of gestation. After having been matched with the control group regarding mother's parity and year of birth, the overall risk of stillbirth was found to be marginally higher (1.1 fold) in ART children after adjusting for factors such as maternal age and the child's sex.