Depression may be associated with an increased risk of arterial narrowing in the legs and pelvis, a condition known as peripheral artery disease (PAD), according to research presented at the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology 2012 Scientific Sessions in Chicago.
While experts know that depression is a risk factor for constricted heart arteries, its effect on PAD is uncertain. Researchers used data from 1,024 men and women in the Heart and Soul Study and followed them for about seven years.