Culture

There's no innovation crisis in drug development, according to a new article, the real crisis stems from current incentives that reward companies for developing large numbers of new drugs with few clinical advantages over existing ones.

It has recently been suggested that patients should be kept alive using elective ventilation to facilitate the harvesting of organs for donation. But David Shaw, Honorary Lecturer at the University of Aberdeen believes there is a much simpler way to increase the number of donated organs – by ensuring that doctors respect the wishes of the deceased and over-rule any veto.

Conflict-of-interest statements made by physicians and scientists in their medical journal articles after they had been allegedly paid by pharmaceutical manufacturers as part of off-label marketing programs are often inadequate, highlighting the deficiencies in relying on author candidness and the weaknesses in some journal practices in ensuring proper disclosure.

Participants in a study who were normal weight at the time of a diagnosis of diabetes experienced higher rates of total and noncardiovascular death compared with those who were overweight or obese at diabetes diagnosis, according to a study in JAMA.

CHICAGO --- American adults of a normal weight with new-onset diabetes die at a higher rate than overweight/obese adults with the same disease, according to a new Northwestern Medicine study.

The study, to be published in the Aug. 7 issue of JAMA, found that normal-weight participants experienced both significantly higher total and non-cardiovascular mortality than overweight/obese participants.

Significantly more children got health insurance coverage after increases in federal matching funds to states for Medicaid and the Children's Health Insurance Program (CHIP), according to new research from the University of Michigan.

The 14 years of wildlife studies in and around Madagascar's Ranomafana National Park by Sarah Karpanty, associate professor of wildlife conservation at Virginia Tech's College of Natural Resources and Environment, and her students are summarily part of a paper on biodiversity published July 25 by Nature's Advanced Online Publication and coming out soon in print.

WINSTON-SALEM, N.C. – August 6, 2012 – When a stroke patient is discharged from the hospital, they often must cope with a new disability or lack of function, so changes in their medications or a new dosing prescription can be particularly confusing. This can lead the patient to overmedicate, take the wrong medication or skip medications entirely and can result in being readmitted to the hospital.

PROVIDENCE, R.I. [Brown University] — In a touch-screen display or a solar panel, any conductive overlay had better be clear. Engineers employ transparent thin films of indium tin oxide (ITO) for the job, but a high-tech material's properties are only half its resume. They must also be as cheap and easy to manufacture as possible. In a new study, researchers from Brown University and ATMI Inc. report the best-ever transparency and conductivity performance for an ITO made using a chemical solution, which is potentially the facile, low-cost method manufacturers want.

COLUMBIA, Mo. — The unemployment rate differences among white males, women and minorities have decreased during the past few decades in the United States, but persistent inequalities continue among the groups, according to a study by an economist at the University of Missouri. Understanding these hidden differences in employment could help educators and policy makers develop more effective programs aimed at reducing unemployment inequality.

Corticosteroids, frequently prescribed to alleviate acute sinusitis, show no clinical benefit in treating the condition, according to a randomized controlled trial published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/press/cmaj.120430.pdf.

CAMBRIDGE, Mass. -- Even temporary rises in local temperatures significantly damage long-term economic growth in the world's developing nations, according to a new study co-authored by an MIT economist.

Looking at weather data over the last half-century, the study finds that every 1-degree-Celsius increase in a poor country, over the course of a given year, reduces its economic growth by about 1.3 percentage points. However, this only applies to the world's developing nations; wealthier countries do not appear to be affected by the variations in temperature.

PHILADELPHIA – Greening vacant lots may make neighborhood residents feel safer and may be associated with reductions in certain gun crimes, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. Results show that residents living near greened vacant lots feel safer than those near non-greened sites. Additionally, researchers noted that incidents of police-reported crimes may be reduced after greening.

gned comprehensive behavioral therapy is more effective than sessions offering patient support and education in helping adults with Tourette syndrome manage their tics – sudden, repetitive motions or vocalizations – according to a study in the August issue of Archives of General Psychiatry. The findings come from a team of investigators at Massachusetts General Hospital (MGH)/Harvard Medical School, Yale University, the University of Texas Health Science Center at San Antonio, and other institutions.

gher levels of physical activity were related to lower risk of death in patients with diabetes, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication.