Researchers at Moffitt Cancer Center and colleagues have investigated the safety, efficacy and the maximum tolerated dose of pomalidomide for patients with multiple myeloma who have disease relapsed after treatments with other drugs, such as bortezomib and lenalidomide. This phase I clinical trial enrolled 38 patients, and pomalidomide provided a minimal or better response for 42 percent of the patients, a partial response or better for 21 percent, and a complete response for 3 percent.
Culture
Pneumonia cannot be accurately diagnosed solely on a doctor's analysis of symptoms and patient history, according to new findings.
A new study, published online today (24 January 2013) ahead of print in the European Respiratory Journal, found that a majority of pneumonia cases could not be accurately diagnosed by a doctor's judgement alone, compared to a chest radiograph.
[Emergency medical admissions, deaths at weekends and the public holiday effect. Cohort study Online First doi 10.1136/emermed-2012—2-1881]
Patients admitted to hospital as emergencies on public holidays are significantly more likely to die than those admitted on other days of the week - including weekends - indicates research published online in Emergency Medicine Journal.
COLLEGE PARK, Md. – Filipinos have been an invisible minority in Annapolis, Maryland for more than a century. Now, researchers at the University of Maryland are using oral histories as a way to flesh out their life and times – documenting the incredible challenges they faced – and successes they celebrated.
DURHAM, N.C. -- Duke University engineers are layering atom-thick lattices of carbon with polymers to create unique materials with a broad range of applications, including artificial muscles.
The lattice, known as graphene, is made of pure carbon and appears under magnification like chicken wire. Because of its unique optical, electrical and mechanical properties, graphene is used in electronics, energy storage, composite materials and biomedicine.
As the gun control debate continues, Kevin D. Bradford, an associate professional specialist in marketing at the University of Notre Dame's Mendoza College of Business, says the focus should be on those who distribute guns, not solely on those who buy them.
ITHACA, N.Y. – Working-class couples that buck convention and live together rather than marry take on traditional roles when it comes to housework, according to a new study by a Cornell University sociologist.
Cohabiting women do a disproportionate share of the housework, even when the women work and the men don't – and even when the women want to share the housework more equally, said co-author Sharon Sassler, Cornell professor of policy analysis and management.
A new USC study finds evidence suggesting that the brain works hard to understand those who have different bodies when watching them in action.
According to the study's lead author, the finding supports initiatives to include more individuals with physical differences in mainstream media – such as Sarah Herron, a contestant on ABC's The Bachelor this season, who was born with a foreshortened left arm.
Retirement involves a set of institutional arrangements combined with socio-cultural meanings to sustain a distinct retirement phase in life course and career pathways. The articles outline that recent forces of change may lead to reinvention of retirement. There are factors that must be recognized as having a significant impact such as the fact that life expectancy and health status of adults over 60 has increased dramatically in recent years. Reinvention could involve change to one or more of the institutional arrangements supporting retirement.
HERSHEY, Pa. -- People who receive primary care from free clinics are less likely to use the emergency department for minor issues, according to a team of medical researchers.
Nationally, the number of emergency departments (EDs) has decreased yet the number of ED visits has gone up, the team reported. Therefore, it is important to figure out how to reduce unnecessary ED visits.
According to the National Association of Free and Charitable Clinics, there are more than 1,200 free clinics nationwide. Many of these clinics work in cooperation with one of their local hospitals.
In a study designed to see if doctors who are told the exact price of expensive medical tests like MRIs in advance would order fewer of them, Johns Hopkins researchers got their answer: No.
In a report published online in the Journal of the American College of Radiology, the researchers found that revealing the costs of MRIs and other imaging tests up front had no impact on the number of tests doctors ordered for their hospitalized patients.
Researchers at the University of Granada, Spain, have designed a new computing system that determines the age and sex of a corpse with a reliability of 95%. This system is based on free software called Image and a free DICOM displayer called K-Pacs. This state-of-the-art system is very different from the traditional macroscopy systems used to evaluate the osteoarticular features of a corpse, and it is much faster and user-friendly.
Technological advancements in medicine have allowed patients suffering from musculoskeletal conditions such as hip and knee pain to regain mobility and live relatively pain-free. But some "high risk" surgical devices that have been approved by the U.S. Food and Drug Administration (FDA) are not required to go through clinical trials, where a product is tested to determine its safety and effectiveness.
- Lower minimum legal drinking age (MLDA) laws have been associated with short-term effects such as more traffic fatalities and teen suicides.
- A new study has investigated the long-term and persistent effects of permissive MLDA laws.
- Findings support an association with problematic drinking behaviors that persist into later adulthood, such as more frequent binge episodes.
- Adolescence is often a time of novelty seeking and risk taking, including the initiation of drinking.
- Other risk factors are also involved in trajectories of alcohol use that may develop over time.
- A new study has identified six different trajectories of alcohol use from adolescence into adulthood.