Using a selective screening strategy for prostate cancer may reduce the harms associated with testing while preserving the number of lives saved.
Measuring blood levels of prostate-specific antigen (PSA) can help doctors determine which patients may be at risk for prostate cancer. Patients with an elevated PSA level may require a biopsy to determine if cancer is present. However, biopsies are associated with many troublesome side effects and still cannot tell a doctor with certainty which cases of prostate cancer are life-threatening and require treatment.