Vitamin C seems to be particularly beneficial for people under heavy physical stress. In five randomized trials of participants with heavy short-term physical stress, vitamin C halved the incidence of the common cold.
Three of the trials studied marathon runners, one studied Swiss school children in a skiing camp and one studied Canadian soldiers during a winter exercise.
Furthermore, in a recent randomized trial carried out with adolescent competitive swimmers, vitamin C halved the duration of colds in males, although the vitamin had no effect on females.