Culture

Bethesda, MD (April 29, 2013) — Pregnant women with mid to high levels of antibodies common in patients with celiac disease are at risk for having babies with reduced fetal weight and birth weight, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. The antibody tissue transglutaminase (anti-tTG) is most commonly found in patients with celiac disease.

Bethesda, MD (April 29, 2013) — A commonly used class of biologic response modifying drugs can cause acute liver injury with elevated liver enzymes, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. Patients with inflammatory diseases such as Chron's disease or ulcerative colitis often are prescribed tumor necrosis factor-alpha (TNF-α) antagonists, which modify the body's response to infection.

As states continue to grapple with aging correctional facilities, overcrowding, underfunded retiree obligations and other constraints, new research from Temple University's Center for Competitive Government finds that privately operated prisons can substantially cut costs – from 12 percent to 58 percent in long-term savings – while performing at equal or better levels than government-run prisons.

While all heart attacks have the potential to be deadly, one type is referred to as the "widow maker" because of its high risk of death. A ST segment elevation myocardial infarction (STEMI) is a severe type of heart attack that occurs when a blockage in a coronary artery causes heart muscle to die; without prompt treatment risk of fatality increases dramatically. Coronary angioplasty, or percutaneous coronary intervention (PCI), is the most common emergency treatment for STEMI.

Rochester, MN, April 29, 2013 –Unethical behavior among physicians-in-training threatens to erode public trust and confidence in the medical profession, say two academic physicians in the current issue of Mayo Clinic Proceedings. Reacting to CNN reports last year about the widespread use of "recalls" and "airplane notes" by radiology and dermatology residents, Gregory W. Ruhnke, MD, MS, MPH, of the Department of Medicine, University of Chicago, and David J.

The fixed combination of the drugs saxagliptin and metformin (Komboglyze®) has been approved in Germany since November 2011 for the treatment of type 2 diabetes mellitus. In an early benefit assessment pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this fixed combination product offers an added benefit versus the current standard treatment. Such an added benefit cannot be derived from the dossier, however, as the manufacturer did not submit any relevant data.

Having to explain how a political policy works leads people to express less extreme attitudes toward the policy, according to new research published in Psychological Science, a journal of the Association for Psychological Science.

The research suggests that people may hold extreme policy positions because they are under an illusion of understanding — attempting to explain the nuts and bolts of how a policy works forces them to acknowledge that they don't know as much about the policy as they initially thought.

PROVIDENCE, R.I. [Brown University] — Alternately praised in the aftermath of horrible tragedies as a heroic service and lamented in policy debates as an expensive safety net for people without primary care, emergency medicine is often a hot topic. Despite that importance, an analysis published online April 26 in the Annals of Emergency Medicine finds that national expenditures on emergency care are likely significantly higher than previously thought.

ST. LOUIS – A recent Saint Louis University study revealed that Medicaid-insured children with eczema, an inflammatory skin condition that affects 20 percent children in the United States, do not have easy access to dermatologists.

"This is a complex problem and a major health disparity in our country," said Elaine Siegfried, M.D., professor of pediatrics at SLU and the principal investigator of the study. "Thirty percent of all children seen in primary care offices have a skin problem. It's an everyday issue."

ORLANDO – Residents living in areas near natural gas operations, also known as hydraulic fracturing, or fracking, are concerned their illnesses may be a result of nearby drilling operations. Twenty-two percent of the participants in a small pilot study surmise that hydrofracking may be the cause of such health concerns as sinus problems, sleeping difficulties, and gastrointestinal problems.

The findings will be presented at the American Occupational Health Conference on April 28 in Orlando, Florida.

Sophia Antipolis, 26 April 2013. A practical guide on the use of the new oral anticoagulants (NOACs) has been produced by the European Heart Rhythm Association (EHRA) of the European Society of Cardiology (ESC). A guide was needed to summarise existing information on different drugs, to answer clinical questions that fall outside what drug companies can legally answer, and to make distinctions between the different drugs.

In seeming contrast to the notion that the elderly often have memory problems, a new study from an HF/E researcher finds driver retraining to be an effective strategy for improving the safe-driving habits of older drivers over the long term.

Amsterdam, The Netherlands, Friday 26 April 2013: A study presented today at the International Liver CongressTM 2013 – which evaluated the relationship between non-alcoholic fatty liver disease (NAFLD), early predictors of atherosclerosis and the 10-year Framingham risk score (FRS) – showed that NAFLD increases the risk of early atherosclerotic lesions independent of established cardiovascular (CV) risk factors.

Amsterdam, The Netherlands, Friday 26 April 2013: Data from a number of clinical trials presented today at the International Liver Congress™ 2013 shed new light on the use of TACE and SIRT in the treatment of hepatocellular carcinoma (HCC).

Transarterial chemoembolization (TACE) is a technique in which small particles designed to block blood vessels mixed or coated with chemotherapeutic drugs are injected directly into an artery supplying the tumour; it has become a standard treatment in selected patients with HCC.

Amsterdam, The Netherlands, Friday 26 April 2013: New data from two clinical trials presented today at the International Liver Congress™ 2013 demonstrate substantial improvements in the detection of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) using diagnostic urine tests.