WASHINGTON, DC — A preclinical study led by researchers at Children's National Medical Center has found that a new oral drug shows early promise for the treatment of Duchenne muscular dystrophy (DMD). The results, published in EMBO Molecular Medicine, show that the drug, VBP15, decreases inflammation and protects and strengthens muscle without the harsh side effects linked to current treatments with glucocorticoids such as prednisone.
Culture
(Edmonton) Researchers at the University of Alberta have developed a synthetic peptide that could be the first in a new class of drugs to treat heart disease, high blood pressure and diabetes.
Researchers at the U of A found that a deficiency in the peptide apelin is associated with heart failure, pulmonary hypertension and diabetes. They also developed a synthetic version that targets pathways in the heart and promotes blood vessel growth.
DETROIT – Heart patients' mental state and thinking abilities may help predict whether costly and potentially dangerous early hospital readmission will follow their release after treatment, according to the results of a significant new study by Henry Ford Hospital researchers.
The findings have important implications for the health care industry as it struggles to contain unnecessary costs, according to the study's lead author, Mark W. Ketterer, Ph.D., a psychologist and administrator for Henry Ford.
The study is published online in Psychosomatics.
The National Heart Centre Singapore (NHCS) research team has successfully and completely reversed the effects of the hERG (human ether-a-go-go-related gene) mutation in long QT syndrome 2 (LQTS 2) in patient-specific heart cells, scoring a world's first. Long QT syndrome 2 is a dangerous heart rhythm disorder that can lead to sudden cardiac death, even in young patients. It is caused by a mutation in a specific gene known as hERG, which helps to control the electrical activity in the heart cells and coordinate its beating rhythm.
More children than ever before are living with a debilitating digestive disease, research has shown.
Scientists have found that coeliac disease affects six times more children living in Scotland now than it did in 1990.
A team from the University of Edinburgh and Queen Margaret University analysed the health records of children from South East Scotland aged under 16 years who were newly diagnosed with the condition between 1990 and 2009.
Using a simple survey tool, a team of researchers has done what complex studies have failed to do -- provide data that identifies starting points for preventing diarrheal disease outbreaks in at least one region of Africa.
Diarrheal illness is a leading cause of disease and death in children under 5, and in HIV-plagued Botswana, it is a significant issue for those over 5 as well.
Raleigh-Durham, NC. -- A new meta-analysis of 29 randomized studies involving more than 4,500 patients with knee osteoarthritis (OA) found that intra-articular hyaluronic acid (HA) injections provided significant improvement in pain and function compared to saline injections.
The first of its kind, the review showed 461 cases of links between racism and child and youth health outcomes.
Lead researcher Dr Naomi Priest at the McCaughey VicHealth Centre for Community Wellbeing at the University of Melbourne said the review demonstrated racism as an important factor influencing the health and wellbeing of children and youth.
TORONTO, September 17, 2013 – A review study published today finds that financial incentives –as modest as $5 per week – can increase the amount of exercise people do.
Lead author Marc Mitchell, University of Toronto PhD candidate and Cardiac Rehabilitation Supervisor at Toronto Rehab, worked under the leadership of University of Toronto exercise psychologist Guy Faulkner and exercise physiologist Jack Goodman to publish these findings in the September online publication of the American Journal of Preventive Medicine.
The review study looked at 1,500 patients.
Philadelphia, September 17, 2013 -- The American College of Physicians (ACP) sets the framework for a team-based model of health care in a new policy paper published today in the peer-reviewed medical journal, Annals of Internal Medicine. ACP offers more than a dozen principles to encourage and enable clinicians to work together effectively in dynamic clinical care teams.
CHICAGO – A higher proportion of women than men 55 years and younger did not have chest pain in acute coronary syndromes (ACS, such as heart attacks or unstable angina), although chest pain was the most common symptom for both sexes, according to a study published by JAMA Internal Medicine, a JAMA Network publication.
Walter A. Rocca, M.D., M.P.H., of the Mayo Clinic, Rochester, Minn., and colleagues examined the incidence of dementia with Lewy bodies (DLB) and Parkinson disease dementia (PDD) in a study of residents in Olmsted County, Minn., over a 15-year period.
Limited information is available about the incidence of DLB or PDD in the general population so researchers used a well-defined population to help better characterize the two disorders, according to the study background.
Reliable quantum computing would make it possible to solve certain types of extremely complex technological problems millions of times faster than today's most powerful supercomputers. Other types of problems that quantum computing could tackle would not even be feasible with today's fastest machines. The key word is "reliable." If the enormous potential of quantum computing is to be fully realized, scientists must learn to create "fault-tolerant" quantum computers.
TORONTO, Sept. 13, 2013 – If aboriginal women had the same income and education levels as non-aboriginal women, their risk of being abused by a partner could drop by 40 per cent, according to a new study by researchers at St. Michael's Hospital.
The new study indicates that socio-economic position is a major factor influencing risks of abuse for aboriginal women.
High drug expenses in Canada are a substantial barrier for people to access prescription drugs outside of hospital, states an analysis in CMAJ (Canadian Medical Association Journal).