Culture

Low levels of both oxygen and the powerful blood vessel dilator nitric oxide appear to have an unfortunate synergy for patients with sickle cell disease, researchers report.

Their studies indicate that the two conditions common in sickle cell disease, dramatically increase red blood cells' adhesion to the lining of blood vessels walls and the debilitating pain crises that can result.

A pilot scheme allowing patients to visit GPs outside the area they live in was most popular among younger commuters and people who had moved house but did not want to change their GP, according to a new report by the London School of Hygiene & Tropical Medicine.

If you're rigid with rules and skimpy on affection and dialogue with your kids, they have a greater chance of being obese, according to research presented at the American Heart Association's Epidemiology & Prevention/Nutrition, Physical Activity & Metabolism Scientific Sessions 2014.

Building a strong connection to a social group helps clinically depressed patients recover and helps prevent relapse, according to a new study.

For the paper, Canadian Institute for Advanced Research (CIFAR) Senior Fellow Alexander Haslam, lead author Tegan Cruwys and their colleagues at the University of Queensland conducted two studies of patients diagnosed with depression or anxiety. The patients either joined a community group with activities such as sewing, yoga, sports and art, or partook in group therapy at a psychiatric hospital.

Interim analysis of the intergroup EORTC-LYSA-FIL 20051 H10 trial published in the Journal of Clinical Oncology indicates an increased risk of early relapse when omitting radiotherapy in early PET scan negative patients with stage I/II Hodgkin's lymphoma. Early outcome, however, was excellent in both arms, and the final analysis should reveal whether these initial findings are maintained over time.

Fortunately, more and more people survive critical illnesses and accidents. A new Danish-American survey shows, however, that hospitalisation where the patient has received mechanical ventilation can have serious consequences:

- Of course, the good news is that more and more patients survive critical illness and treatment using ventilators. But at the same time, the bad news is that we have now documented that the ventilator patients have a considerable risk of developing psychological problems.

TALLAHASSEE, Fla. — Some doctors are too quick to prescribe antidepressants to parents who have suffered the death of a child either during pregnancy or within the first month of life, according to a study conducted by Florida State University researcher Jeffrey R. Lacasse.

In a study of 235 bereaved parents participating in an online support community, Lacasse found that 88 — or 37.4 percent — of them were prescribed a psychiatric medication to help them cope. Some women received prescriptions with a week of losing their children.

EAST LANSING, Mich. — Stopping massive data breaches like the one that hit Target will require a more sophisticated, collaborative approach by law enforcement agencies around the world, a Michigan State University cyber security expert argues.

Consuming alcohol more frequently than twice a week increases the risk of stroke mortality in men, according to a study carried out at the University of Eastern Finland. The results show that the effects of alcohol are not limited to the amount consumed, but also the frequency of drinking matters. The results were published in Acta Neurologica Scandinavica on 8 March.

A physically active lifestyle and occasional drinking is associated with a reduced risk of developing visual impairment, according to a study published online this month in Ophthalmology, the journal of the American Academy of Ophthalmology.

Poisons are silent, effective and cheap, making the especially dangerous in Africa where they are used for both pest control and illegal poaching. However, as a new study in Annals of the New York Academy of Sciences reveals, they also kill un-intended wildlife.

Michael Clarke, Consultant Ophthalmologist at Newcastle Eye Centre, says that apart from trauma and orthopaedics, ophthalmology receives more NHS outpatient referrals than any other speciality.

He says that opticians are constrained by legislation to refer patients to a medical practitioner if abnormalities are found at an NHS sight test. However, the testing done at NHS sight tests has become more complex and many patients are now referred with clinically insignificant abnormalities, leading to wastage of appointments in Hospital Eye Services.

Critically ill patients receiving mechanical ventilation had a higher prevalence of prior psychiatric diagnoses and an increased risk of a new psychiatric diagnosis and medication use after hospital discharge, according to a study in the March 19 issue of JAMA.

Using a patient's age to raise the threshold for an abnormal result of a blood test used to assess patients with a suspected pulmonary embolism (blood clot in lungs) appeared to be safe and led to fewer healthy patients with the diagnosis, according to a study in the March 19 issue of JAMA.

The German Institute for Quality and Efficiency in Health Care (IQWiG) already assessed the added benefit of ipilimumab in advanced melanoma in 2012. A considerable added benefit was found for patients who had already received previous treatment. In the new dossier compiled by the drug manufacturer, the drug was now compared with the appropriate comparator therapy dacarbazine specified by the Federal Joint Committee (G-BA) also for non-pretreated patients.