Culture

New research, published in The Lancet Psychiatry journal, shows that rates of adverse outcomes, including premature death and violent crime, in people with schizophrenia are increasing, compared to the general population.

Individuals who are hospitalized for the skin conditions of Stevens-Johnson syndrome and toxic epidermal necrolysis appear to have a high risk of recurrence, according to a study in the June 4 issue of JAMA.

In a study that included nearly 65,000 older patients hospitalized with pneumonia, treatment that included azithromycin compared with other antibiotics was associated with a significantly lower risk of death and a slightly increased risk of heart attack, according to a study in the June 4 issue of JAMA.

An examination of the benefit of preventive placement of implantable cardioverter-defibrillators (ICDs) in patients with a less severe level of heart failure, a group not well represented in clinical trials, finds significantly better survival at three years than that of similar patients with no ICD, according to a study in the June 4 issue of JAMA.

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health suggests that new therapies for kidney disease could be developed more quickly by revising the definition of kidney disease progression used during clinical trials. If adopted, the new definition could shorten the length of some clinical trials and also potentially encourage more clinical trials in kidney disease. The findings will be published in the June 3, 2014 online edition of the Journal of the American Medical Association.

Philadelphia, PA, June 3, 2014 – Severe aortic stenosis (AS) has a grave prognosis with 25-50% of patients dying within a year once symptoms develop. Transcatheter aortic valve replacement (TAVR) represents a paradigm shift in the therapeutic options for these patients. Because of cost and availability issues, there are often waiting times for this procedure. Investigators have found that even modest increases in wait times have a substantial impact on the effectiveness of TAVR in individuals who need it the most: otherwise inoperable patients and high-risk surgical candidates.

At least 10 percent of people who have a heart attack may have undiagnosed diabetes, according to new research presented at the American Heart Association's Quality of Care and Outcomes Research Scientific Sessions 2014.

Researchers studied data on 2,854 heart attack patients who did not have a known diagnosis of diabetes in 24 U.S. hospitals to understand the prevalence and recognition of undiagnosed diabetes. They tested the patients' A1C levels, which is a standard test to determine blood sugar levels for the past 2-3 months.

Researchers found:

Chinese stroke patients were less likely to acquire pneumonia or die from the stroke when hospitals followed treatment guidelines, according to research presented at the American Heart Association's Quality of Care and Outcomes Research Scientific Sessions 2014.

Closer adherence to the American Heart Association/American Stroke Association's Get With The Guidelines®-Stroke led to a drop in pneumonia from 20 percent to almost 5 percent.

However, only 55.5 percent of patients received all guideline-recommended treatments for which they were eligible.

June 3, 2014 - Standardized research methods are needed to make greater progress toward reducing the high burden and costs of chronic low back pain (cLBP), according to a Task Force report in the June 15 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

A new survey of Canadian physicians shows a "significant gap" between optimal practices to detect nutrition problems in hospitalized patients and what action is actually taking place.

Women age 55 or younger may fare worse than their male counterparts after having a heart attack, according to new research presented at the American Heart Association's Quality of Care and Outcomes Research Scientific Sessions 2014.

Researchers studied records and interviews of 3,501 people (67 percent women) who had heart attacks in the United States and Spain in 2008-12. One year after their heart attack, women were more likely than men to have:

ANN ARBOR—If all eye doctors prescribed the less expensive of two drugs to treat two common eye diseases of older adults, taxpayer-funded Medicare plans could save $18 billion over a 10-year period, say researchers at the University of Michigan.

Bottom Line: The percentage of physicians making campaign contributions in federal elections increased to 9.4 percent in 2012 from 2.6 percent in 1991, and during that time physician contributors shifted away from Republicans toward Democrats, especially in specialties dominated by women or those that are traditionally lower paying such as pediatrics.

Author: Adam Bonica, Ph.D., of Stanford University, California, and colleagues.

Bottom Line: Researchers found no evidence of an "obesity paradox" (some studies have suggested overweight or obese patients have lower mortality rates than underweight or normal weight patients) in patients with stroke.

Author: Christian Dehlendorff, M.S., Ph.D., of the Danish Cancer Society Research Center, Copenhagen, Denmark, and colleagues.

COLUMBIA, Mo. –The majority of adults aged 65 and older remains inactive and fails to meet recommended physical activity guidelines, previous research has shown. However, these studies have not represented elders living in retirement communities who may have more access to recreational activities and exercise equipment.