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Boston, MA -- New findings, presented today at the American College of Cardiology, provide long-term information about survival, stroke rates and durability of a novel centrifugal-flow pump compared with a commercial axial flow pump for heart-failure patients. BWH investigators report that patients who received the centrifugal-flow pump had significantly lower rates of pump-related blood clots and stroke. Results from the MOMENTUM 3 trial's analysis at 24 months were presented in a Late Breaking Clinical Trial at ACC by Mandeep R.

DURHAM, N.C. -- Doctors evaluating patients for blockages in the heart are aided by having a good roadmap of the vascular terrain before they can insert stents to clear the impasse.

Two technologies have been used with equal success, but now a study presented March 10 at the American College of Cardiology annual meeting by Duke cardiologists shows that the newer method carries a much lower cost, potentially saving each patient at least $800.

NEW ORLEANS, LA - Nonoperative treatment of high school athletes with shoulder instability is an effective approach, according to research presented today at the American Orthopaedic Society for Sports Medicine's Specialty Day in New Orleans. Researchers also noted that using the Non-Operative Instability Severity Score (NSIS) tool can help identify higher-risk patients who may require other forms of treatment.

NEW ORLEANS, LA - Isolated femoral condyle lesions account for 75% of the cartilage repair procedures performed in the knee joint, and physicians have a variety of techniques to consider as part of surgical treatment. Osteochondral allograft transplantation (OCA) is a valuable and successful approach for this condition, as described by research presented today at the American Orthopaedic Society for Sports Medicine's Specialty Day in New Orleans.

During some kinds of blood donations, you get most of your blood back. For example, platelet donation involves a procedure in which donor blood is filtered to harvest the platelets for medical use and the rest of the blood components are returned to the donor's body. The byproducts of this procedure - a fraction of immune cells - are typically discarded.

March 9, 2018 - High-altitude areas--particularly the US intermountain states--have increased rates of suicide and depression, suggests a review of research evidence in the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.

Ocean conditions off most of the U.S. West Coast are returning roughly to average, after an extreme marine heat wave from about 2014 to 2016 disrupted the California Current Ecosystem and shifted many species beyond their traditional range, according to a new report from NOAA Fisheries' two marine laboratories on the West Coast. Some warm waters remain off the Pacific Northwest, however.

BUFFALO, N.Y. - The absence of a protein critical to the control of inflammation may lead to rapid and severe bone loss, according to a new University at Buffalo study.

The study found that when the gene needed to produce the protein tristetraprolin (TTP) is removed from healthy mice, the animals developed the bones of much older rodents.

Within nine months, mice without the gene experienced a nearly 20 percent loss in oral bone. The results also revealed that overexpressing TTP in the animals led to a 13 percent reduction in bone turnover compared to unaffected mice.

Water is crucial for life, but how do you make water? Cooking up some H2O takes more than mixing hydrogen and oxygen. It requires the special conditions found deep within frigid molecular clouds, where dust shields against destructive ultraviolet light and aids chemical reactions. NASA's James Webb Space Telescope will peer into these cosmic reservoirs to gain new insights into the origin and evolution of water and other key building blocks for habitable planets.

CHICAGO (March 9, 2018): For many years, people who sustained severe burn injuries often died. But great strides in burn care over the last 30 years have dramatically increased their chances of survival, according to new study findings published as an "article in press" on the Journal of the American College of Surgeons website ahead of print publication.

Alport Syndrome (AS) is a hereditary kidney disease caused by a genetic mutation leading to type IV collagen (Col4) abnormalities. Unfortunately, treatment through the correction of Col4 functionality has not yet been developed. Now, researchers from Kumamoto University in Japan have established a highly sensitive technology to assess Col4 functionality thereby paving the way to develop therapeutic drugs.

A research team ECOSOS (Evolving Cooperation and Social Simulation) led by Hitoshi Yamamoto from Rissho University develops a game theoretical method to analyze what role the diversity of social norms plays in the process of evolving cooperation. The team revealed that a social norm that regards those who help the bad as bad becomes extinct if the members of the society learn their norms based on "dividualism".

A new study by scientists from WCS (Wildlife Conservation Society) and other groups predicts that the effects of climate change will severely impact the Albertine Rift, one of Africa's most biodiverse regions and a place not normally associated with global warming.

A newly-discovered hereditary mutation is responsible for an increased production of erythropoietin (EPO) in the blood. This mutation causes a messenger RNA (mRNA) that is not normally involved in the formation of proteins to be reprogrammed so that it produces EPO, thus abnormally increasing the number of red blood cells. Researchers from the Department of Biomedicine at the University of Basel and University Hospital Basel reported these findings in The New England Journal of Medicine.

LA JOLLA, CA - March 8, 2018 - About 1 in 2,500 people have a degenerative nerve disease called Charcot-Marie-Tooth (CMT). The disease is typically diagnosed in children, who can lose their ability to walk and use their hands for fine motor skills. There is no cure--yet.

Scientists at The Scripps Research Institute (TSRI) have now shown a path to developing treatments for disease subtype CMT2D. As they report in the journal Nature Communications, it may be possible to reverse the disease by using a small molecule to restore normal protein function in the nervous system.