Culture
Jean-François Côté, a researcher at the Montreal Clinical Research Institute (IRCM) and professor at Université de Montréal's Faculty of Medicine, studies metastasis, the leading cause of cancer-related death. Recently, his team uncovered a protein that, once deactivated, could prevent the development of metastases in an aggressive type of cancer, HER2-positive breast cancer.
One in eight women will be diagnosed with breast cancer in her lifetime and one in 30 is expected to die from it. The findings, published in the journal Cell Reports, could improve this prognosis.
Data from almost 600 participants show that women's perceptions of male attractiveness do not vary according to their hormone levels, in contrast with some previous research. The study findings are published in Psychological Science, a journal of the Association for Psychological Science.
A new study published in Nature Communications shows that infants who are later diagnosed with autism react more strongly to sudden changes in light. This finding provides support for the view that sensory processing plays an important role in the development of the disorder.
Scientists from Germany, Denmark and the UK have built a model tool to predict what happens to marine animals when exposed to noise from the construction and operation of windfarms at sea. Using the North Sea harbor porpoise (Phocoena phocoena) population as a case study, they demonstrate how the model can be used to evaluate the impact of offshore wind farm construction noise. This type of noise is increasingly prevalent due to the high demand for green energy, and currently there are >900 offshore wind farms at various stages of development in Europe alone.
If dead cells accumulate in the body, they can contribute to inflammation and pre-dispose individuals to multiple chronic inflammatory conditions such as rheumatoid arthritis, cardiovascular diseases, Crohn's disease or lupus by uncharacterized pathways.
TORONTO, May 5, 2018 - Hospitals caring for children with serious, chronic illness are highly dependent on public payers, according to a new study. The research found that proposals to dramatically reduce federal expenditures on Medicaid and Children's Health Insurance Program (CHIP) could destabilize current specialty care referral networks serving all children, including the majority of privately-insured children in greatest need of high quality, specialized, pediatric care.
TORONTO, May 5, 2018 - Research on transgender teens' and their parents' attitudes regarding fertility preservation will be presented during the Pediatric Academic Societies (PAS) 2018 Meeting in Toronto. A new study found that while more research is needed on the subject, fertility preservation is a major factor for only a minority of transgender teens and their parents in deciding to delay hormone therapy.
TORONTO, May 5, 2018 - A new study examines the effectiveness of the ScreenQ, a measure of screen-based media use in children. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2018 Meeting.
TORONTO, May 5, 2018 - Selective serotonin reuptake (SSRI) antidepressant treatment during pregnancy is associated with better performance on a computerized task to measure cognitive skills in 12 year olds, according to a new study being presented during the Pediatric Academic Societies (PAS) 2018 Meeting.
TORONTO-(May 5, 2018)-Clinicians caring for vulnerable babies in the neonatal intensive care unit (NICU) need to closely monitor their vital signs, but precisely gauging the function of their tiny hearts has remained elusive.
TORONTO-(May 5, 2018) - Erythropoietin (EPO) helps to protect and repair vulnerable brains though it remains a mystery how the anemia drug does so. Genetic analyses conducted by a multi-institutional research team finds that EPO may work its neuroprotective magic by modifying genes essential for regulating growth and development of nervous tissue as well as genes that respond to inflammation and hypoxia. Findings from the pilot study will be presented during the Pediatric Academic Societies 2018 annual meeting.
Stiffer breast tissue creates an environment more prone to cancer by enabling the disease to interfere with the surrounding healthy cells, according to a recent study published in Biomaterials.
Scientists studying tumor growth and metastasis at the University of Notre Dame fabricated a human tissue model to examine how cancer cells interact with connective tissue in the breast. The model allowed the team to control the stiffness of the tissue, mimicking both healthy and cancerous breast tissue structures. They found manipulation of fat cells to be stiffness-dependent.
The most abundant molecule in cell membranes is the lipid phosphatidylcholine (PC, commonly known as lecithin); accordingly, the enzymes responsible for synthesizing it are essential. Research published in the May 4 issue of the Journal of Biological Chemistry used computer simulations to gain insights into how one of these enzymes activates and shuts off PC production. These results could help researchers understand why small changes in this enzyme can lead to conditions like blindness and dwarfism.
Cold Spring Harbor, NY - During a stroke or an epileptic seizure, neurons in affected parts of the brain fire at an abnormally rapid rate. One byproduct of this condition is that the pH of the brain drops markedly, rendering the local environment inhospitably acidic.
Using a powerful microscopy method called cryo-EM, biologists at Cold Spring Harbor Laboratory (CSHL) have discovered how one key element of brain physiology, a docking port for excitatory neurotransmitters called the NMDA receptor, is able to function in this hostile environment.
People showing virtually no symptoms are likely the primary source of dengue fever, according to new research published in PLOS Pathogens. Nearly 400 million people each year are infected with dengue virus, which is transmitted through mosquitoes.