Culture
New research from the University of British Columbia suggests that reducing mutated Huntington disease protein in the brain can restore cognitive and psychiatric impairments in mice.
Huntington disease (HD) is a genetic, progressive disorder that causes mental decline, psychiatric problems and uncontrolled movements. The disease is caused by mutant huntingtin (HTT) protein, with symptoms appearing in adulthood and worsening over time.
Published today in the Journal of the American Geriatrics Society (JAGS), two new research articles and a corresponding commentary from preeminent geriatrics leaders describe ways to make person-centered care--a novel approach to health that puts personal values and preferences at the forefront of decision-making--more actionable for older people.
One of the weirdest objects in the Milky Way just got weirder. Scientists have discovered a new source of the highest-energy photons in the cosmos: a strange system known as a microquasar, located in our neck of the galaxy a neighborly 15,000 light years from Earth. The discovery could shed light on some of the biggest, baddest phenomena in the known universe.
Following surgery, some patients experience a broken bone around the implants of a total hip replacement--called a periprosthetic femoral fracture. In a study of such patients published in the Journal of Bone and Mineral Research, investigators found that 8.3% of patients had atypical femoral fractures, which are a rare type of femoral stress fracture. The researchers also found a strong association between use of bisphosphonates and risk of atypical femoral fractures.
In a Pigment Cell & Melanoma Research article, world-leading experts identify emerging frontiers in skin cancer and pigment diseases.
Melanoma is a deadly type of skin cancer that arises from pigment-forming cells. The article challenges the field by addressing provoking questions in melanoma immunotherapy, cancer systems biology, medical and surgical oncology, pigment biophysics, and precision prevention of skin diseases such as melanoma.
By analysing survey data from 1999-2001 and 2010-2012, researchers have estimated the demand for commercial sex among British men.
The Scottish Journal of Political Economy study found that men traveling abroad, men living in London, drug users, religious men, and men with middle-class income are more often together with prostitutes than other men.
A research group from Chalmers University of Technology, Sweden, has made great, rapid strides towards the development of a specially designed molecule which can store solar energy for later use. These advances have been presented in four scientific articles this year, with the most recent being published in the highly ranked journal Energy & Environmental Science.
While many cancer therapies initially can be very successful, tumors often return and spread when remaining cancer cells develop resistance to treatment. To combat this tendency, Frédéric Thomas of the French National Centre for Scientific Research proposes that cancer researchers take a lesson from our own immune system and explore "natural adaptive therapies." Such an approach would mimic the immune system's more restrained way of keeping cancer in check by gradually killing off cancerous cells.
BOSTON (Oct. 2, 2018, 2:00 p.m. ET)--Poor eating is a major cause of illness, especially from cardiometabolic conditions such as heart disease, type 2 diabetes, and obesity. These diseases generate large economic burdens for both government and private insurance programs. For individuals and their families, additional burdens come in the form of personal illness, out-of-pocket costs, reduced quality of life, and a shortened lifespan. These diet-related diseases and costs disproportionately affect low-income families in the United States.
BUFFALO, N.Y. -- University at Buffalo childhood obesity experts are praising a study published Monday in JAMA Pediatrics that rigorously assessed how the home environments of young children who are genetically at high risk for obesity can influence whether they become overweight or obese.
"The study's main finding was that genetic influences on children's body mass index (BMI) depends upon their home environment," said Myles S. Faith, PhD, professor of counseling, school and educational psychology in the UB Graduate School of Education.
U of T scientists use nanoparticles to improve chemotherapy response and boost anti-tumor immunity in breast cancer
BUFFALO, N.Y. - Being a good neighbor can have a powerful effect on residents' attitudes and behaviors even for those living in highly disadvantaged communities, according to the results of a new study by a University at Buffalo sociologist.
At 11 am EDT (1500 UTC) on Oct 1 , Kong-rey was located near 16.8 north and 134.4 east, about 488 miles north-northwest of Yap. It was moving to the northwest and had maximum sustained winds near 125 knots gusting to 150 knots. Currently the only threatened landmasses are the Ryuku Islands.
AUGUSTA, Ga. (Oct. 2, 2018) - A member of a protein family known for protecting our cells also protects cancer cells in aggressive, metastatic breast cancer, scientists report.
Induction of heat shock protein 70, or HSP70, - which protects cells from stress - appears to be a key difference between difficult-to-treat triple negative breast cancer and the more responsive estrogen-positive breast cancer, says Dr. Hasan Korkaya, tumor biologist at the Georgia Cancer Center and Department of Biochemistry and Molecular Biology at the Medical College of Georgia at Augusta University.
ITHACA, NY - You might not have heard of the groundcherry, or at least, never tasted one. But that could soon change thanks to research from the Van Eck Laboratory at Boyce Thompson Institute (BTI).
The groundcherry (Physalis pruinosa) is approximately the same size as a cherry tomato, but with a much sweeter flavor. The tropical-tasting fruit is also a powerhouse in terms of nutritional value. Packed with Vitamin C, Vitamin B, beta-carotene, phytosterols, and antioxidants, plus anti-inflammatory and medicinal properties, this tiny fruit might just be the next superfood.