Culture

INDIANAPOLIS - In a commentary published in JAMA Internal Medicine, three Regenstrief Institute research scientists write that while they and other researchers have identified a strong and consistent link between anticholinergic drugs and cognitive impairment from observational studies, randomized clinical trials represent the only rigorous method to definitively establish a causal relationship between these frequently used drugs and various dementias.

Patients with type 1 diabetes have to regularly inject themselves with insulin, a hormone that helps their cells absorb glucose from the bloodstream. Another hormone called glucagon, which has the opposite effect, is given to diabetic patients to revive them if they become unconscious due to severe hypoglycemia.

Boston, MA -- Every three minutes, a food-related allergic reaction sends someone to the emergency room in the U.S. Currently, the only way to prevent a reaction is for people with food allergies to completely avoid the food to which they are allergic. Researchers are actively seeking new treatments to prevent or reverse food allergies in patients. Recent insights about the microbiome -- the complex ecosystem of microorganisms that live in the gut and other body sites -- have suggested that an altered gut microbiome may play a pivotal role in the development of food allergies.

Berkeley -- The rise of anti-immigration rhetoric and policies in the United States following the 2016 presidential election may be taking its toll on the health of California's Latinx youth, including those who are U.S. citizens, suggests a new study led by University of California, Berkeley, researchers.

Scientists at Harvard University, collaborating with researchers at Bio-Rad Laboratories, have developed a new platform for rapid single-cell sequencing. The approach combines microfluidics and novel software to scale up single-cell ATAC-seq, which identifies parts of the genome that are open and accessible to regulatory proteins.

Published in Nature Biotechnology, the innovation signals a major acceleration in single-cell genomics research.

What is single-cell sequencing?

Nestled between the Pacific Ocean and the Andes mountains, Peru's coastal region relies on surface water from the Andes for drinking water, industry, and animal and crop farming.

The region, which includes Peru's capital city Lima, is often overwhelmed with rain in the wet season - but by the time the dry season comes, water is scarce.

These factors, together with Lima's rapidly growing population, mean the city struggles to supply water to its 12 million residents during the dry months of May to October.

HANOVER, N.H. – June 24, 2019 –Using smartphones, fitness bracelets and a custom app, researchers have created a mobile-sensing system that judges employee performance.

The system works by monitoring the physical, emotional and behavioral well-being of workers to classify high and low performers.

The latest supplement to the American Ornithological Society's checklist of North and Middle American birds is being published in The Auk: Ornithological Advances, and it includes several major updates to the organization of the continent's bird species. The official authority on the names and classification of the region's birds, the checklist is consulted by birdwatchers and professional scientists alike and has been published since 1886.

Logging roads are expanding dramatically in the Congo Basin, leading to catastrophic collapses in animal populations living in the world's second-largest rainforest, according to research co-led by a scientist at James Cook University in Australia.

Just as worrying is that the rate of forest destruction caused by new roads in the Congo Basin has risen sharply over time, quadrupling since 2000.

In a study using brain tissue from deceased human donors, Johns Hopkins Medicine researchers say they found new evidence that schizophrenia can be marked by the buildup of abnormal proteins similar to those found in the brains of people with such neurodegenerative disorders as Alzheimer's or Huntington's diseases.

A large-scale study from The University of Toledo of young African Americans who have attempted or died by suicide suggests there is a greater need for mental health services in urban school districts, and that we need to do a better job in convincing parents and caregivers to safely secure firearms and ammunition in the home.
Taking those measures, Dr. James Price said, could save lives.

Years before symptoms of Alzheimer's disease appear, two kinds of damaging proteins silently collect in the brain: amyloid beta and tau. Clumps of amyloid accumulate first, but tau is particularly noxious. Wherever tangles of the tau protein appear, brain tissue dies, triggering the confusion and memory loss that are hallmarks of Alzheimer's.

Scientists from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences and their collaborators investigated the mechanism of rapid reactivity of the F + H2 reaction at low temperature and found that rapid reactivity was actually induced by resonance-enhanced tunneling.

This finding explains the observation of HF in interstellar clouds, which is generated only through the F + H2 reaction. The research was published in Nature Chemistry.

The project gives valuable new insights on how genetic adjustments through evolution have rendered the ruminants one of the most successful groups of animals on the planet. The results have recently been published in three articles in the acknowledged scientific journal Science.

Approx. 20 million years ago, ruminants began to outmatch all other groups of large herbivores. Today ruminants count more than 200 species from all ecosystems and in all sizes, ranging from 2 to 1500 kg.

A new study has found that variability in night-to-night sleep time and reduced sleep quality adversely affect the ability of older adults to recall information about past events. The study also found unexpected racial differences in the type of sleep patterns tied to lower memory performance across both younger and older African American research participants.