Culture
In a surprise find, scientists have discovered sugar-coated RNA molecules decorating the surface of cells.
These so-called "glycoRNAs" poke out from mammalian cells' outer membrane, where they can interact with other molecules. This discovery, reported May 17, 2021, in the journal Cell, upends the current understanding of how the cell handles RNAs and glycans.
DALLAS, May 17, 2021 -- Detecting a critical heart defect before birth (congenital heart defects) is less likely when a mother lives in a rural area, lives in a neighborhood with low socioeconomic status or is Hispanic, according to new research published today in the American Heart Association's flagship journal Circulation.
Diagnosing a heart defect before birth reduces infant death rates, increases access to prompt medical treatment, improves neurodevelopmental outcomes and decreases the risk of brain injury for the infant after birth.
What The Study Did: Researchers assessed the feasibility of using positive behavior supports to promote the use of face coverings in school-aged children with autism spectrum disorders and/or attention-deficit/hyperactivity disorder (ADHD) attending a summer program during the COVID-19 pandemic.
Authors: Benjamin Aaronson, Ph.D., of the University of Washington in Seattle, is the corresponding author.
Early diagnosis and improvement of breast cancer treatments have reduced breast cancer mortality in recent years, with survival rates reaching 85% today. In spite of these data, breast cancer was still the most frequently diagnosed tumour in the world in 2020, mainly due to increased population screening and social factors such as ageing. RANK protein plays a key role in the development of these tumours. Located in the membrane of cells, when it binds to its partner RANKL, it sends signals that stimulate the development of the mammary gland.
Doctors often recommend Omega-3s to help patients lower their cholesterol and improve heart health. Those Omega-3s can come from fatty fish like salmon and mackerel, or supplements that often contain a combination of the acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
Mitochondria - the 'batteries' that power our cells - play an unexpected role in common diseases such as type 2 diabetes and multiple sclerosis, concludes a study of over 350,000 people conducted by the University of Cambridge.
The study, published today in Nature Genetics, found that genetic variants in the DNA of mitochondria could increase the risk of developing these conditions, as well influencing characteristics such as height and lifespan.
In the largest genetic study of bipolar disorder to date, researchers have identified 64 regions of the genome containing DNA variations that increase risk of bipolar disorder - more than double the number previously identified.
A study published in the scientific journal Addiction provides the most comprehensive evidence to date of the association between recreational cannabis laws (RCLs) in US states and responses in the illegal markets for cannabis, heroin, and other drugs in those states.
Gears and mechanical transmissions are at home in the Emilia-Romagna region, the Motor Valley of northern Italy. A team of researchers from the University of Bologna and the Institute for Organic Synthesis and Photoreactivity of the National Research Council (Cnr-Isof) in Bologna, led by Massimo Baroncini and Alberto Credi, has planned, constructed and operated NanoGear, a device consisting of interlocked molecular components and designed to function as a gear.
Humans leave their "footprints" on the land area all around the globe. These land-use changes play an important role for nutrition, climate, and biodiversity. Scientists at the Karlsruhe Institute of Technology (KIT) combined satellite data with statistics from the past 60 years and found that global land-use changes affect about 32 percent of the land area. This means that they are about four times as extensive as previously estimated. The researchers publish their findings in the scientific journal Nature Communications.
The cover for issue 7 of Oncotarget features Figure 14, "A hypothetical model of how a specific remodeling of cellular metabolism by CR slows down yeast chronological aging," published in "Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors" by Mohammad, et al.
A research group from Kumamoto University, Japan has discovered that cysteinylated albumin (oxidized albumin) in serum can be used as an early diagnostic marker for diabetic kidney disease. Compared with urinary albumin, serum oxidized albumin not only reflects renal pathology at an earlier stage, but can also predict the progression of renal pathology by its degree of elevation. The researchers believe that it can be used as a new diagnostic marker for early diagnosis of diabetic kidney disease.
Tsukuba, Japan--Researchers at the University of Tsukuba found that, despite only covering about one-third of the distance in HIIT compared with that covered in endurance training, similar improvements in exercise capacity and brain function were observed for both forms of exercise.
The way in which banks react to climate risks and uncertainty could impact financial stability as well as the world's transition to a low-carbon economy. A new study by researchers from IIASA and the Vienna University of Economics and Business explored the role that banks' expectations about climate-related risks will play in fostering or hindering an orderly low-carbon transition.
Devices that deliver nicotine without smoke inhalation have potential to help smokers who cannot or do not want to stop using nicotine to reduce dramatically the risk of smoking-related disease and death.
However, for smokers to switch to these alternatives, the products need to provide what smokers expect from cigarettes.
The newest study from Queen Mary University of London evaluates safety and effects of these products and has focused on the most popular "heat not burn" product, IQOS.