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At a glance:

Over eight years, patients covered under a global budget payment model for doctors and hospitals showed slower spending growth and better quality than comparable populations mostly under the traditional fee-for-service model.

Patients whose providers were paid by the global payment model for eight years spent nearly 12 percent less on medical claims than the comparison population.

The concept of a carbon budget has become a popular tool in guiding climate policy since the Intergovernmental Panel on Climate Change's (IPCC) Fifth Assessment Report was released in 2014. IIASA researchers were involved in the development of a framework that can help scientists determine which factors affect the size of the remaining carbon budget and how they interact.

A promising vaccine that clears an HIV-like virus from monkeys is closer to human testing after a new, weakened version of the vaccine has been shown to provide similar protection as its original version.

Two newly discovered organisms point to the existence of an ancient organism that resembled a tiny version of the lumbering, human-eating science fiction plants known as 'triffids,' according to research in Nature.

The microscopic protists Rhodelphis limneticus and Rhodelphis marinus are genetically 'sisters' to red algae, but couldn't be more different. Red algae are fleshy, large organisms with a simple genome that perform photosynthesis, just like plants. Rhodelphis are single-cell predators with a large, complex genome.

A group of scientists led by 2018 Australian of the Year Professor Michelle Simmons have achieved the first two-qubit gate between atom qubits in silicon - a major milestone on the team's quest to build an atom-scale quantum computer. The pivotal piece of research was published today in world-renowned journal Nature.

Baylor College of Medicine researchers, in collaboration with the University of California, Los Angeles and Second Sight Medical Products (Los Angeles, Calif.) are using a visual cortical prosthesis to help bring sight to the blind. The study is in the early phases but participants are able to see points of light on a computer screen using a device called Orion. To put it simply, researchers are bypassing broken optical nerves that don't work and inputting visual information seen by a camera, worn on a pair of glasses, directly into the Orion device implanted in the brain.

New Marketing Science Study Key Takeaways:

Research shows once recreational marijuana is legalized, the number of online searches for tobacco increase by 8%, while searches for alcohol drop by 11%.

The findings could have an implication on sales for the alcohol and tobacco industries.

The passing of recreational cannabis increases online searches for cannabis done by adults by 17%, but not by youth.

The community of viruses is staggeringly vast. Occupying every conceivable biological niche, from searing undersea vents to frigid tundra, these enigmatic invaders, hovering between inert matter and life, circumnavigate the globe in the hundreds of trillions. They are the most abundant life forms on earth.

BUFFALO, N.Y. -- University at Buffalo researchers have determined that a human gene present in 75 % of the population is a key reason why a class of drugs for Alzheimer's disease seemed promising in animal studies only to fail in human studies.

The researchers say the work suggests that in different Alzheimer's disease patients, different mechanisms are at work that determine whether or not a given therapy will be effective.

ANN ARBOR--Roughly 11% of high school seniors reported prescription drug misuse during the past year, and of those, 44% used multiple supply sources, according to a pair of University of Michigan studies.

More than 70% of adolescents who obtained prescription drugs from multiple sources had a substance use disorder--involving prescription medications, other drugs and alcohol--within the previous year.

The national average for a substance use disorder for all adolescents is 5%, said senior author Sean Esteban McCabe, a professor at the U-M School of Nursing.

Marine protected areas, or MPAS, are an increasingly common way of protecting marine ecosystems by prohibiting fishing in specific locations. However, many people remain skeptical that MPAs actually benefit fish populations, and there has not yet been a way to demonstrate whether or not they are effective. Until now.

Infants who develop eczema are more likely to develop food allergies, hay fever and asthma as they grow older, a progression known as the atopic march. Donald Leung, MD, PhD, head of Pediatric Allergy & Clinical Immunology at National Jewish Health, has identified itching and dry cracked skin of eczema patients as a significant promoter of the atopic march. Moisturizers, especially early in a child's life, may help prevent eczema, food allergies and other allergic diseases.

A quarter of women who have serious maternal complications during childbirth also have premature births, posing a "dual burden" on families, finds research from NYU Rory Meyers College of Nursing, the University of California, San Francisco (UCSF) California Preterm Birth Initiative, and Stanford University.

The study, published online in The Journal of Maternal-Fetal & Neonatal Medicine and the first to focus specifically on "dual burden" births, shows that these complications occur in one of 270 births and are twice as likely to affect Black mothers.

A University of Massachusetts Amherst environmental epidemiologist studying the presence of PFAS compounds in new mothers and their babies found that women with gestational diabetes had a "significantly higher" rate of transferring the synthetic chemicals to their fetus.

What The Study Did: In this secondary analysis of a randomized clinical trial, researchers examined the association of age with the benefit of intensive treatment to lower lipid levels with a combination therapy of simvastatin and ezetimibe compared to treatment with simvastatin alone after acute coronary syndrome in older patients.

Authors: Richard G. Bach, M.D., of Washington University School of Medicine in St. Louis, is the corresponding author.

(doi:10.1001/jamacardio.2019.2306)