Culture

WASHINGTON (Feb. 10, 2020) - The human protein apolipoprotein A-I binding protein (AIBP) inhibits HIV replication by targeting lipid rafts and reducing virus-cell fusion, according to a new study published in the premier American Society for Microbiology journal mBio by researchers from the George Washington University. These results provide the first evidence suggesting that AIBP is an innate immunity factor that restricts HIV replication by modifying lipid rafts on cells targeted by HIV.

Researchers at the Biozentrum of the University of Basel have discovered a "clockwork" mechanism that controls cell division in bacteria. In two publications, in "Nature Communications" und "PNAS", they report how a small signaling molecule starts the "clock", which informs the cell about the right time to reproduce.

Radiation from dying stars is luminous enough to easily spin up orbiting asteroids to break-up speed

New study led by University of Warwick astronomer computes the cascade of destruction down to boulder-size fragments

Break-ups form a vast asteroid debris field much like the classic arcade game, including fragments which revolve around each other as "double asteroids"

Scientists predict that the Solar System's asteroid belt will be pulverised by the Sun's light in 6 billion years

A recent study finds that corporate financial managers do a great job of detecting signs of potential fraud, but are less likely to voice these concerns externally when their company is under pressure to meet a financial target.

Researchers have developed a model that could boost investment in farm-based sustainable energy projects by allowing investors to more accurately predict whether a project will turn a profit. The model improves on earlier efforts by using advanced computational techniques to address uncertainty.

A place-based payroll tax incentive can be effective in stimulating employment in remote and underdeveloped regions, helping to address regional inequalities, according to a new UCL and University of Oslo study.

The way research in bioprinting will be taken forward has been laid out in a roadmap for the field.
Published today in IOP Publishing's Biofabrication, leading researchers define the status, challenges and opportunities in the field, and forecast the required advances in science & technology to overcome the challenges to a range of bioprinting techniques and applications.

In the roadmap:

Hospitals, doctors and Medicare Advantage insurance plans that care for some of the most vulnerable patients are not reimbursed fairly by Medicare, according to recent findings in JAMA.

Health insurance costs weigh heavily on the minds of many middle-aged adults, and many are worried for what they'll face in retirement or if federal health policies change, according to a new study just published in JAMA Network Open.

A population of microorganisms living in our intestine, known as the gut microbiota, plays a crucial role in controlling our metabolism and reducing the risk of conditions such as obesity and diabetes.

The Clostridium difficile pathogen takes its name from the French word for "difficult." A bacterium that is known to cause symptoms ranging from diarrhea to life-threatening colon damage, C. difficile is part of a growing epidemic of concern for the elderly and patients on antibiotics.

Outbreaks of C. difficile-infected cases have progressively increased in Western countries, with 29,000 reported deaths per year in the United States alone.

Chronic pain, or inflammation, is believed to be one of the major factors in the onset of major depressive disorder. Therefore, to better understand what happens physiologically during depression, scientists have long studied several metabolic processes or "pathways" related to inflammation. One of these pathways, called the kynurenine pathway, is the principal pathway involved in metabolizing the amino acid tryptophan.

Scientists at Tokyo Institute of Technology have shown that copper oxide particles on the sub-nanoscale are more powerful catalysts than those on the nanoscale. These subnanoparticles can also catalyze the oxidation reactions of aromatic hydrocarbons far more effectively than catalysts currently used in industry. This study paves the way to better and more efficient utilization of aromatic hydrocarbons, which are important materials for both research and industry.

A calf was born from an embryo lacking cells which form a large part of the placenta, providing new insight into the regenerative capacity of mammalian embryos.

Mammalian development starts from a single cell -- a fertilized egg. The egg goes through multiple cell divisions to increase its cell numbers and then starts forming a sphere-like structure with a cavity inside, called the blastocyst. The blastocyst consists of two types of cells, the inner cell mass (ICM) and the trophectoderm (TE), which develop into an embryo proper and a large part of the placenta, respectively.

The novel coronavirus 2019-nCoV is making headlines worldwide. Since there is no specific therapy against it, the prevention of infection is of particular importance in order to stem the epidemic. Like all droplet infections, the virus can spread via hands and surfaces that are frequently touched.