Culture
PORTLAND, Ore. - Gene-infused nanoparticles used for combating disease work better when they include plant-based relatives of cholesterol because their shape and structure help the genes get where they need to be inside cells.
The findings by Oregon State University researchers, published today in Nature Communications, are important because many illnesses that can't be treated effectively with conventional drugs can be treated genetically - delivering nucleic acids to diseased cells so they can make the correct proteins needed for health.
Historical wood panel paintings with developed craquelure patterns - networks of fine cracks in the paint- are significantly less vulnerable to environmental variations than previously assumed, according to a study in the open access journal Heritage Science. The findings offer a potential explanation as to why heavily cracked historical paintings remain stable in environments far from 'ideal' museum conditions.
Bioengineers at the University of California San Diego have developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer. By programming CAR T cells to switch on when exposed to blue light, the researchers controlled the cells to destroy skin tumors in mice without harming healthy tissue.
People aged 65 years and over are less likely to be readmitted to hospital if they are given help with their medication for three months after discharge, new research from the University of Bradford (UK) has found.
The palaeontologists found the remains of the ancient amphibian at the Berezovsky quarry, a fossil locality in the Krasnoyarsk Krai near the town of Sharypovo. Fossils of ancient fish, various reptiles, mammals, herbivorous and predatory dinosaurs have been previously found there. The research materials were collected on field expeditions in the mid-2010s.
The study, a collection of molecular data from bird species found across 41 oceanic archipelagos, reveals how the area and isolation of islands are key to determining the diversity of species they contain.
Bottom Line: Researchers compared long-term quality of life and patient satisfaction among those patients who were treated with antibiotics or who had their appendix removed for uncomplicated acute appendicitis. Evidence in recent years has indicated antibiotic treatment is a safe and efficient alternative to appendectomy. This study was a seven-year follow-up of a randomized clinical trial in Finland of patients with uncomplicated acute appendicitis who underwent appendectomy or who received antibiotics.
What The Study Did: Researchers compared treatment and survival rates between African American and white women following early detection with mammography of triple-negative breast cancer. African American women have a higher rate of death from breast cancer compared with white women, a disparity partly explained by a higher rate of this aggressive breast cancer.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
What The Study Did: The large health care system Kaiser Permanente Northern California provides universal screening for prenatal cannabis use in women during pregnancy by self-report and urine toxicology testing. This observational study used data to examine the association of depression, anxiety, and trauma diagnoses and symptoms with cannabis use by women during pregnancy.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
What The Study Did: This analysis estimated the health and economic consequences of indoor tanning regulations, such as banning indoor tanning devices or prohibiting their use by minors, in North America and Europe compared with current levels of use.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Authors: Louisa G. Gordon, Ph.D., of QIMR Berghofer Medical Research Institute in Brisbane, Australia, is the corresponding author.
New research has identified a clear accountability gap in the current Freedom of Information (FOI) legislation when it comes to outsourced public services.
The research, which focused on outsourcing through Private Finance Initiative (PFI), found high levels of non-disclosure due either to refusal/partial refusal or non-response to FOIs.
PHILADELPHA -- Machine learning is helping Penn Medicine researchers identify the size and shape of brain networks in individual children, which may be useful for understanding psychiatric disorders. In a new study published today in the journal Neuron, a multidisciplinary team showed how brain networks unique to each child can predict cognition.
NEW YORK, NY (February 19, 2020) - A global community of over 150 scientists studying the primate brain has released a blueprint for developing more complete "wiring diagrams" of how the brain works that may ultimately improve understanding of many brain disorders.
SINGAPORE, 20 February 2020 - Publishing in the prestigious New England Journal of Medicine today, an international research collaboration led by Professor Tazeen H.
AURORA, Colo. (Feb. 19, 2020) - A novel, four-week parenting rotation designed for pediatric residents has dramatically increased the amount of time resident parents can spend at home with their babies, according to a study by researchers at the University of Colorado Anschutz Medical Campus.
The elective, created in 2010 by physicians at the University of Colorado School of Medicine, was set up to address the lack of maternity leave for doctors in residency programs, a time when many get pregnant.