Culture
UC Davis MIND Institute researchers found an unexpected set of mental illnesses in patients with a spectrum of a rare genetic disorder. Their study revealed the need for clinicians to consider the complexities of co-existing conditions in patients with both psychological and fragile X associated disorders.
Double-hit fragile X spectrum cases
The patients had a "double-hit" condition that combined features and symptoms of fragile X syndrome and premutation disorder.
In many countries, sharing a bed with a partner is common practice. Yet, research investigating the relationship between bed sharing and sleep quality is both scarce and contradictory. Most studies have compared co-sleep to individual sleep in couples by only measuring body movements. However, Dr. Henning Johannes Drews of the Center for Integrative Psychiatry (ZIP), Germany and colleagues overcame these limitations by also assessing sleep architecture in couples that shared a bed.
An article in CMAJ (Canadian Medical Association Journal) provides an overview on personal protective equipment (PPE) in health care settings, including evidence on effectiveness of N95 masks, as well as the importance of including health care worker perspectives on usage of this equipment. http://www.cmaj.ca/lookup/doi/10.1503/cmaj.200575
To manage Canada's emergency stockpile of medical supplies and personal protective equipement (PPE), the government could consider several approaches, including a "prime-vendor" model selling directly to health care organizations to minimize financial and equipment waste, according to an article in CMAJ (Canadian Medical Association Journal)
Lecce, 25th June 2020 - Gold nanoparticles have been developed in the laboratory in order to reduce the cell death of neurons exposed to overexcitement. The study, is the result of an international collaboration coordinated by Roberto Fiammengo, researcher at the Center of Biomolecular Nanotechnologies of the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) in Lecce (Italy).
The Ik, a small ethnic group in Uganda, are not incredibly selfish and mean as portrayed in a 1972 book by a prominent anthropologist, according to a Rutgers-led study.
Instead, the Ik are quite cooperative and generous with one another, and their culture features many traits that encourage generosity, according to the study in the journal Evolutionary Human Sciences.
In recent years, the number of women who entered U.S. medical school surpassed the number of men. But gender inequities still exist in many areas of medicine.
The ability to sequence the genome of a tumor has revolutionized cancer treatment over the last 15 years by identifying drivers of cancer at the molecular level. But understanding the genetic diversity of individual cells within a tumor and how that might impact the disease progression has remained a challenge, due to the current limitations of genomic sequencing.
As far as humans are concerned, bacteria can be classified as either harmful, pathogenic bacteria and harmless or beneficial non-pathogenic bacteria. To develop better treatments for diseases caused by pathogenic bacteria, we need to have a good grasp on the mechanisms that cause some bacteria to be virulent. Scientists have identified genes that cause virulence, or capability to cause disease, but they do not fully know how bacteria evolve to become pathogenic.
CATONSVILLE, MD, June 23, 2020 - The weight loss industry in the United States is vast and generates about $20 billion each year from over 100 million dieters. Commercial weight loss programs design customer-focused program policies to shape and optimize satisfaction and development. These two metrics are tied to how well a program does and the success of the customers in that program. New research in the INFORMS journal Marketing Science finds one key to success is making sure you have the right role model for dieters.
How do environmental exposures during pregnancy and childhood influence the risk of obesity in children? The Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, and the University of Southern California led the first major study to investigate the associations between many pollutants and environmental factors --77 prenatal and 96 childhood exposures-- and the risk of childhood obesity.
What The Study Did: This randomized clinical trial evaluates the effect of treatment with colchicine on cardiac and inflammatory biomarkers and clinical outcomes in patients hospitalized with COVID-19.
Authors: Spyridon G. Deftereos, M.D., Ph.D., of the National and Kapodistrian University of Athens in Greece, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2020.13136)
What The Article Says: A man in his 60s presented with numerous pseudovesicular papules on the trunk 12 hours after the initiation of treatment for COVID-19.
Authors: Laurence Toutous Trellu, M.D., of the Geneva University Hospitals in Switzerland, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamadermatol.2020.1966)
What The Article Says: This essay describes observations of the qualities developed by hospital staff members during the COVID-19 pandemic.
Author: Megha Prasad, M.D. M.S., of the Columbia University Irving Medical Center in New York, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamacardio.2020.2240)
Life depends on an intricate game of hide-and-seek taking place inside the cell. New research, which is now published in the journal Nature, sheds light on the mechanisms with which DNA-binding proteins search the genome for their specific binding sites.