Culture

LA JOLLA--(September 8, 2020) Salk scientists have used skin cells called fibroblasts from young and old patients to successfully create blood vessels cells that retain their molecular markers of age. The team's approach, described in the journal eLife on September 8, 2020, revealed clues as to why blood vessels tend to become leaky and hardened with aging, and lets researchers identify new molecular targets to potentially slow aging in vascular cells.

African wild dogs have a vestigial first digit and muscular adaptations for life on the run

Anatomists identify a vestigial first digit in the forelimb of the African wild dog and document anatomical adaptations to its unique lifestyle of long-distance running and exhaustive predation

Probiotics may help children and adolescents with obesity lose weight when taken alongside a calorie-controlled diet, according to a study being presented at e-ECE 2020. The study found that obese children who were put on a calorie-restricted diet and given probiotics Bifidobacterium breve BR03 and Bifidobacterium breve B632, lost more weight and had improved insulin sensitivity compared with children on a diet only.

Patients with autoimmune inflammation of their thyroid may be at greater risk of developing anxiety, according to a study being presented at e-ECE 2020. The study found that people with anxiety may also have inflammation in their thyroid gland that can be reduced by taking the non-steroidal anti-inflammatory, ibuprofen. These findings suggest that thyroid function may play an important role in the development of anxiety disorders and that thyroid inflammation should be investigated as an underlying factor in psychiatric disorders, such as anxiety.

COVID-19 patients can suffer long-term lung and heart damage but, for many, this tends to improve over time, according to the first, prospective follow-up of patients infected with the coronavirus, presented at the European Respiratory Society International Congress. [1]

If you have not been hearing much of the French Gilets Jaunes or of the Italian Sardines in the last few months, it's because "the social and psychological unrest arising from the epidemic tends to crowd-out the conflicts of the pre-epidemic period, but, at the same time it constitutes the fertile ground on which global protest may return more aggressively once the epidemic is over," writes Massimo Morelli, Professor of Political Science at Bocconi, in a paper recently published in Peace Economics, Peace Science and Public Policy.

As the flu season approaches, a strained public health system may have a surprising ally -- the common cold virus.

Rhinovirus, the most frequent cause of common colds, can prevent the flu virus from infecting airways by jumpstarting the body's antiviral defenses, Yale researchers report Sept. 4 in the journal The Lancet Microbe.

The findings help answer a mystery surrounding the 2009 H1N1 swine flu pandemic: An expected surge in swine flu cases never materialized in Europe during the fall, a period when the common cold becomes widespread.

What The Article Says: A hospitalist charts his emotional journey in this narrative essay from when once brightly colored signs declared hospital workers as heroes to now when the signs have faded and the steady and intense work of helping patients with COVID-19 has seemingly become mundane.

Authors: Bernard E. Trappey, M.D., of the University of Minnesota in Minneapolis, is the author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

A trial of a simple yet effective surgery has led Australian experts to promote it as an option to specialists around the world for managing difficult obstructive sleep apnoea (OSA) cases.

After rigorous evaluation of the surgery, excellent outcomes were shown in sleep apnea patients who had been unable to use continuous positive pressure airway (CPAP) treatment, with patients achieved relief from snoring and disrupted sleep and experienced improved general health. according to a new report in the Journal of the American Medical Association (JAMA).

Unequal compensation reduces people's motivation to work, even among those who stand to benefit from unfair advantages, finds a new UCL-led study.

The researchers found that large disparities in rewards offered for the same task reduce people's happiness, which in turn reduce their willingness to work, in the study published in PLOS One.

Lead author, Dr Filip Gesiarz (UCL Psychology & Language Sciences) said: "Here we have shown the psychological impacts of inequality of opportunity, and how it can hurt the productivity and well-being of everyone involved.

Although immune responses are generated by a complex, hierarchical arrangement of immune system organs, tissues, and components, the unit of the cell has a particularly large effect on disease progression and host survival. These cell-level defense mechanisms, known as cell-autonomous immunity, are among the most important determinants of human survival, and are millions to billions of years old, inherited from our prokaryotic and single-celled ancestors.

A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad array of conditions, from allergies and colds to hypertension and urinary incontinence, may be associated with an increased risk of cognitive decline, particularly in older adults at greater risk for Alzheimer's disease (AD).

The hemoglobin in the red blood cells ensures that our body cells receive sufficient oxygen. When the blood pigment is broken down, "heme" is produced, which in turn can influence the protein cocktail in the blood. Researchers at the University of Bonn have now discovered in complex detective work that the "activated protein C" (APC) can be commandeered by heme. At the same time, APC can also reduce the toxic effect of heme. Perspectively, the findings may provide the basis for better diagnostic and therapeutic approaches to blood diseases.

The future economy based on renewable and sustainable energy sources might utilize battery-powered cars, large-scale solar and wind farms, and energy reserves stored in batteries and chemical fuels. Although there are examples of sustainable energy sources in use already, scientific and engineering breakthroughs will determine the timeline for widespread adoption.

CAMBRIDGE, MA - September 2, 2020—Rapid Reviews: COVID-19 (RR:C19), is an open-access overlay journal published by the MIT Press that accelerates peer review of COVID-19-related research preprints to advance new and important findings and prevent the dissemination of false or misleading scientific news.