Culture
Some of the genetic differences that have arisen between domesticated chickens and their wild ancestors, the red junglefowl, are linked to epigenetic changes, according to a new study published in Nature Ecology & Evolution. Scientists at Linköping University in Sweden have discovered a small number of "hotspots" in the DNA that control epigenetic changes at hundreds of other locations throughout the genome.
Capecitabine is a chemotherapy drug used for breast and colorectal Cancer cancer. It can extend survival rate by nearly 10%. However, recent studies revealed that almost 50% of patients develop palmar-plantar erythrodysesthesia, a skin reaction also called hand-foot syndrome with mild to serious symptoms. Up to 17% of these patients can have a burning pain in their hands or feet that can prevent them from doing their usual activities. This adverse reaction is the main cause of dose reductions or therapy delays, with dangerous consequences for cancer patients.
(Boston)-- Responding to the COVID-19 pandemic caused by the novel coronavirus, SARS-CoV-2, requires models that can duplicate disease development in humans, identify potential targets and enable drug testing. Specifically, access to primary human lung in vitro model systems is a priority since a variety of respiratory epithelial cells are the proposed targets of viral entry.
An international team of astrophysicists has found distinctive signatures of black hole event horizon, unmistakably separating them from neutron stars -- objects, comparable to black holes in mass and size but confined within a hard surface. This is by far the strongest steady signature of stellar-mass black holes to date. The team consisting of Mr.
Scientists from the University of Bristol and the Royal Veterinary College (RVC) used three-dimensional computer modelling to investigate the hindlimb of Euparkeria capensis-a small reptile that lived in the Triassic Period 245 million years ago-and inferred that it had a "mosaic" of functions in locomotion.
Doctors like to remind patients not to monkey around with their health, suggesting that a good diet and regular exercise improve longevity.
A new study on health in chimpanzees, which are the closest species to humans genetically, showed the benefits in what they eat and how they can travel and climb.
When chimpanzees have a plant-based diet and substantial opportunities to exercise, they fall into "healthy" human ranges. Lab chimpanzees, whose diet and exercise were limited, showed conditions indicative of cardiovascular disease risk, more like sedentary people.
PITTSBURGH, Sept. 21. 2020 - Researchers at the University of Pittsburgh School of Medicine and Carnegie Mellon University College of Engineering have created a machine-learning algorithm that can detect subtle signs of osteoarthritis--too abstract to register in the eye of a trained radiologist--on an MRI scan taken years before symptoms even begin. These results will publish this week in PNAS.
With this predictive approach, patients could one day be treated with preventative drugs rather than undergoing joint replacement surgery.
September 21, 2020 - The amount Medicare reimburses for orthopaedic trauma surgery has fallen by nearly one-third over the past two decades, reports a study in the Journal of Orthopaedic Trauma.
A discovery of more than a thousand dinosaur teeth, by a team of researchers from the University of Portsmouth, proves beyond reasonable doubt that Spinosaurus, the giant predator made famous by the movie Jurassic Park III as well as the BBC documentary Planet Dinosaur was an enormous river-monster.
Research published today in the journal Cretaceous Research proves that Spinosaurus aegyptiacus, a 15 metre long, six-tonne beast was in fact the most commonly found creature in the Kem Kem river system, which flowed through the Sahara Desert 100 million years ago.
Tokyo, September 21, 2020- The ongoing coronavirus disease 2019 (COVID-19) pandemic has substantially affected patients with dementia and their caregivers. Owing to the restrictive measures taken worldwide to block the spread of COVID-19 outbreaks (including the declaration of a state of emergency in Japan), patients with dementia and their caregivers have not been able to receive the usual support and care. Therefore, this is expected to lead to adverse effects on the patients and their caregivers, and many investigators have warned about the risks (1-3).
An international research team has developed "electronic skin" sensors capable of mimicking the dynamic process of human motion. This work could help severely injured people, such as soldiers, regain the ability to control their movements, as well as contribute to the development of smart robotics, according to Huanyu "Larry" Cheng, Dorothy Quiggle Early Career Professor in the Penn State Department of Engineering Science and Mechanics.
Cheng and collaborating researchers based in China published their work in a recent issue of Nano Energy.
PHILADELPHIA -- New research has uncovered the previously unknown presence of CD19 -- a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma -- in brain cells that protect the blood brain barrier (BBB).
On 8 May 2020, the Institute of Agrifood Research and Technology (IRTA) reported the case of the first cat infected with SARS-CoV-2 in Spain. It was a 4-year-old cat called Negrito, who lived with a family affected by COVID-19, with one case of death. Coinciding with these facts, the animal presented severe respiratory difficulties and was taken to a veterinary hospital in Badalona (Barcelona), where it was diagnosed with hypertrophic cardiomyopathy. Due to a terminal condition the hospital decided to do a humanitarian euthanasia.
Monday, September 21, 2020, CLEVELAND: A new Cleveland Clinic study has found that receiving the influenza vaccine does not increase a person's risk for contracting COVID-19 or worsen associated morbidity or mortality.
By studying 488 public airports in the United States, University of Colorado Denver School of Public Affairs researcher Serena Kim, PhD, found that 20% of them have adopted solar photovoltaic (PV), commonly known as solar panels, over the last decade. Solar photovoltaic (PV) is the conversion of light into electricity using semiconducting materials that exhibit the photovoltaic effect.