Culture
An article published in Bioethics examines the topic of research fatigue--or psychological and emotional exhaustion both towards and as a result of participating in research. The article is meant to initiate a conversation about research fatigue experienced by marginalized communities and how the research community should respond to it.
A study published in Ecological Applications suggests that nature around one's home may help mitigate some of the negative mental health effects of the COVID-19 pandemic.
Food allergies are a big problem. About 7% of children and 2% of adults in the U.S. suffer from some kind of food allergy. These allergies cost a whopping $25 billion in health care each year. Then there's the time lost at school or work. And there's the risk of serious complications, even death.
Surgeons' preoperative expectations were more accurate than patients' expectations in predicting patient-reported outcomes two years after lumbar spine surgery, according to a longitudinal study by investigators at Hospital for Special Surgery (HSS). Most patients had higher expectations than their surgeons did, with many anticipating complete improvement after seeking additional information beyond that provided by their surgeons.
WEST LAFAYETTE, Ind. - Machine learning has been used widely in the chemical sciences for drug design and other processes.
The models that are prospectively tested for new reaction outcomes and used to enhance human understanding to interpret chemical reactivity decisions made by such models are extremely limited.
Purdue University innovators have introduced chemical reactivity flowcharts to help chemists interpret reaction outcomes using statistically robust machine learning models trained on a small number of reactions. The work is published in Organic Letters.
A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma, a connective tissue disorder. The researchers have also shown that LOX can be useful in assessing how well an antifibrotic treatment works, suggesting that it may have potential as a biomarker of fibrosis progression or regression.
A metabolic engineering research group at KAIST has developed an engineered Corynebacterium glutamicum strain capable of producing high-level glutaric acid without byproducts from glucose. This new strategy will be useful for developing engineered microorganisms for the bio-based production of value-added chemicals.
OAK BROOK, Ill. - Racket sports like tennis and racquetball appear to accelerate knee joint degeneration in overweight people with osteoarthritis, according to a study being presented at the annual meeting of the Radiological Society of North America (RSNA).
Knee joint osteoarthritis, a gradual wearing down of the protective cartilage that cushions the ends of the bones, is a major cause of pain and disability worldwide, affecting approximately 14 million people in the U.S. alone. Excess body weight is a major risk factor.
BOSTON - Findings from a team led by investigators at Massachusetts General Hospital (MGH), reported in the online journal mBio, may help scientists develop a more effective vaccine for cholera, a bacterial disease that causes severe diarrhea and dehydration and is usually spread through contaminated water.
BUFFALO, N.Y. -- In the TV series, "How It's Made," viewers often discover that common objects like pencils or rubber bands are quite complicated to make. The show walks people through complex production processes that lie behind familiar items.
A new paper in the journal Cell Reports does the same for saliva.
The study, which will be published on Nov. 17, breaks down, in detail, where the multitude of proteins floating in our saliva originate.
WASHINGTON, November 17, 2020 -- Monitoring how patients with multiple sclerosis or other degenerative diseases use their smartphones could provide valuable information to help get them better treatment.
In an article published in Chaos, by AIP Publishing, researchers used a mobile app to record the keystroke dynamics of a control group and those of subjects in various stages of multiple sclerosis treatment over the course of a year.
Effector regulatory T cells (eTreg cells) are a specialized subset of white blood cells that keep the immune system in check. St. Jude Children's Research Hospital scientists have revealed the metabolic signaling mechanisms that regulate function of eTreg cells. The work may aid efforts to better understand and treat inflammatory diseases. The findings were published online today in Cell Metabolism.
Oak Brook, IL - The December edition of SLAS Discovery, "Drug Discovery Targeting COVID-19" is a special collection assembled by Associate Editor Timothy Spicer (Scripps, FL, USA), focusing on drug discovery efforts toward the current global pandemic of COVID-19caused by the novel coronavirus, SARS-CoV-2.
PULLMAN, Wash. -- Studies conducted in yeast show that exposure to ultraviolet light (UV) induces new types of DNA damage that may cause the deadliest form of skin cancer, malignant melanoma.
That's according to research conducted by a team featuring undergraduate students from Washington State University's School of Molecular Biosciences. The work, led by WSU researchers John Wyrick and Steven Roberts of the College of Veterinary Medicine, was published today, Nov. 17, in Cell Reports.
DALLAS, Nov. 16, 2020 -- Patients with plaque build-up in their arteries, who suffered a transient ischemic attack (TIA) or a minor ischemic stroke, also called a warning stroke, and were treated with the newer blood thinner ticagrelor plus aspirin were 27% less likely to have another stroke within 30 days, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.