Culture

PHILADELPHIA - Marginalized groups of people value professionalism more -- and are more likely to leave a job at an institution due to issues of professionalism -- compared to their white, male counterparts, according to a Penn Medicine study of staff, faculty, and students who were affiliated with a large, academic health system in 2015 and 2017.

CHAMPAIGN, Ill. -- Gut hormones play an important role in regulating fat production in the body. One key hormone, released a few hours after eating, turns off fat production by regulating gene expression in the liver, but this regulation is abnormal in obesity, researchers at the University of Illinois Urbana-Champaign found in a new study.

The study, led by molecular and integrative physiology professor Jongsook Kim Kemper and research scientist Young-Chae Kim, was published in the journal Nature Communications.

The study goals

Predi-COVID was launched with the goal of defining which patient profiles can be associated with a more severe prognosis. The study aims to identify the clinical, epidemiological and socio-demographic characteristics, as well as specific biomarkers from both the SARS CoV-2 virus and the patient, which can help predict the way the disease will evolve in a given individual, according notably to his immune profile.

Predi-COVID and Predi-COVID-H: patient recruitment and operational aspects

A new paper from a UIC researcher shows evidence that suggests sex steroids may play a role in protecting against COVID-19 symptoms.

"Sex and Covid-19: A protective role for reproductive steroids," by Graziano Pinna, research associate professor in psychiatry, analyzes existing research to look at reasons why COVID-19 symptom severity and mortality are more frequent in men than in women and in older people. His paper suggests female reproductive steroids play a protective role.

What should we get for our kids this holiday? As children get older, giving them something they can experience (live through) instead of material things makes them happier, according to new research led by Lan Nguyen Chaplin, associate professor of marketing at the University of Illinois Chicago.

The research, published in the International Journal of Research in Marketing, compared the level of happiness children derive from material goods with the level of happiness they derive from experiences.

Over the past decade, the climate change research community developed a scenario framework that combines alternative futures of climate and society to facilitate integrated research and consistent assessment to inform policy. An international team of researchers assessed how well this framework is working and what challenges it faces.

CLEVELAND -- A new paper from the Department of Psychiatry and the Population Health program at University Hospitals (UH) Cleveland Medical Center, proposes a framework for eliminating defects in behavioral health treatment.

Entitled "Eliminating Defects in Behavioral Health Treatment," the paper was published online on Nov. 19 in the journal Psychiatric Services and was written by Patrick Runnels, M.D., M.B.A., Heather M. Wobbe, D.O., M.B.A., and Peter J. Pronovost, M.D., Ph.D.

Young Brazilians are increasingly interested in biodiversity, conservation of the Amazon and science as they begin high school, but school students in the North region are more interested in learning about these subjects, and about local fauna and flora, than their peers in the Southeast.

Within the past two decades, Johns Hopkins Medicine researchers and others have shown that ketogenic diet therapies -- high-fat, low-carbohydrate and adequate protein diets that metabolize fat into chemicals called ketones that protect the brain and foster healthy neuron growth -- are safe and effective in treating both children and adults with drug-resistant forms of epilepsy. However, while established guidelines are available for using ketogenic diet therapy to reduce seizures in children, there aren't formal recommendations for adults.

The number of young people with anxiety doubled from 13 per cent to 24 per cent, during the early stages of the COVID-19 pandemic and lockdown 1, according to new research from the University of Bristol. The study, using Bristol's Children of the 90s questionnaire data, showed that young people (27-29 years) reported higher levels of anxiety during the early phases of the pandemic in the first national lockdown and this was higher than their parents.

Currently, there are over 10 million confirmed cases and more than 240,000 casualties attributed to COVID-19 in the U.S. Researchers at Louisiana State University have applied computational models to investigate infection rates in relation to social distancing measures. Their paper, Effect of mitigation measures on the spreading of COVID-19 in hard-hit states in the U.S., was recently published in PLOS ONE.

Metabolic robustness, the ability of a metabolic system to buffer changes in its environment, is not always a welcome feature for microbiologists: it interferes with metabolic engineering or prevents that antibiotics kill bacteria. Therefore it is important to understand the mechanisms that enable metabolic robustness. A massively parallel CRISPRi screen demonstrated that E. coli metabolism is very robust against knockdowns of enzymes, and multi-omics data revealed the mechanisms behind it.

Reduced food intake, known as dietary restriction, leads to a longer lifespan in many animals and can improve health in humans. However, the molecular mechanisms underlying the positive effects of dietary restriction are still unclear. Researchers from the Max Planck Institute for Biology of Ageing have now found one possible explanation in fruit flies: they identified a protein named Sestrin that mediates the beneficial effects of dietary restriction.