Culture
Baltimore, MD-- The CRISPR/Cas9 genome editing system can help scientists understand, and possibly improve, how corals respond to the environmental stresses of climate change. Work led by Phillip Cleves--who joined Carnegie's Department of Embryology this fall--details how the revolutionary, Nobel Prize-winning technology can be deployed to guide conservation efforts for fragile reef ecosystems.
Cleves' research team's findings were recently published in two papers in the Proceedings of the National Academy of Sciences.
A University of Ottawa study has found a specific Alzheimer's treatment is effective in male and not female mice, providing a window into the biology of the disease and the effectiveness of targeted treatments.
The paper, 'AB oligomers induce pathophysiological mGluR5 signaling in Alzheimer's disease model mice in a sex-selective manner', published in Science Signaling Magazine highlights the mechanisms underlying Alzheimer's disease are fundamentally different between men and women in regards to one specific treatment.
Using human-induced pluripotent stem cells engineered from a single family's blood samples, a gene signaling pathway linked to a higher risk for developing schizophrenia was discovered by scientists at The University of Texas Health Science Center at Houston (UTHealth). The research was published in a recent issue of Neuropsychopharmacology.
Access to the Internet is essential for economic development, education, global communications, and countless other applications. For all its benefits, however, the Internet has a darker side. It has emerged as a conduit for spreading misinformation, stoking tensions, and promoting extremist ideologies. Yet there is hope.
Oak Brook, IL - The January edition of SLAS Discovery features the cover article, "Cryo-EM: The Resolution Revolution and Drug Discovery" by Taiana Maia de Oliveira, Ph.D., Lotte van Beek, Ph.D., Fiona Shilliday, Ph.D., Judit E. Debreczeni, Ph.D., and Chris Phillips, Ph.D., from AstraZeneca.
A drug typically prescribed for rheumatoid arthritis may also be effective in treating a rare but potentially deadly heart complication some cancer patients experience after taking immunotherapies, according to a study published in Cancer Discovery and co-led by investigators at Vanderbilt University Medical Center (VUMC).
Exposure to mutagens, or mutation-causing agents, can not only bring about changes in DNA but also appear to induce errors when genes are transcribed to make proteins, which may be an important factor in age-related diseases.
The current COVID-19 pandemic has caused over 1 million deaths which can be attributed to its severe progressive pulmonary compromise. The necessity to understand this disease has resulted in detailed analyses of its transmission and clinical aspects published worldwide. In this recent report, doctors in Bolivia provide, who live and work at more than 3,600m from above sea level, a high altitude specialists' perspective.
The existence of GPS-like brain cells, which can store maps of the places we've been, like our kitchen or holiday destination, was already widely known, but this discovery shows there is also a type of brain cell sensitive to the distance and direction of objects that can store their locations on these maps.
Chestnut Hill, Mass. (12/21/2020) - When confronted with comparisons to high status friends and colleagues, consumers prefer to make a "status pivot" into another area where they can shine brighter than their successful peers, according to new research into how consumers respond to status competition, which appears in the Journal of Consumer Research.
LA JOLLA--The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.
"The difference is within us," says Vivek Chandra, Ph.D., an instructor at La Jolla Institute for Immunology (LJI). "We can get infected by the same bacteria or viruses, but the ways our diseases progress can be very different."
Animal toxins are research targets owing to their therapeutic and biotechnological potential. Researchers at the Federal University of the ABC (UFABC), Federal University of São Paulo (UNIFESP) and Federal University of Ceará (UFC) in Brazil have discovered that VmCT1, an antimicrobial peptide isolated from the venom of the scorpion Vaejovis mexicanus, and its analogs kill Trypanosoma cruzi, the parasite that causes Chagas disease. Previous research has demonstrated VmCT1's potential against Gram-positive and Gram-negative bacteria, as well as tumor cells and other protozoans.
DALLAS - Dec. 21, 2020 - A UT Southwestern research team has catalogued gene activity in the skeletal muscle of mice, comparing healthy animals to those carrying a genetic mutation that causes Duchenne muscular dystrophy (DMD) in humans. The findings, published online recently in PNAS, could lead to new treatments for this devastating degenerative disease and insights into factors that affect muscle development.
A new study by Columbia University Mailman School of Public Health researchers poses a hypothetical question: What if air quality improvements in New York City during the spring 2020 COVID-19 shutdown were sustained for five years without the economic and health costs of the pandemic? They estimate cumulative benefits of clean air during this period would amount to thousands of avoided cases of illness and death in children and adults, as well as associated economic benefits between $32 to $77 billion. The study's findings are published in the journal Environmental Research.
Feel like you're suffering from face blindness? Research shows masks change the way we process faces