Culture
Our immune system is never idle. Their task is to detect and eliminate invasive pathogens, and they have no time to lose. The adaptive immune system identifies infectious organisms by recognizing foreign proteins on the surfaces of bacteria, viruses and unicellular protozoans. The interaction of these antigens with immune cells triggers a series of downstream events, which in most cases leads to the elimination of the pathogen.
(Philadelphia, PA) - Like a failing fuel pump that causes a loss of engine power in a car, a diseased heart can take a serious toll on the body's performance. For some patients, tasks like walking up a flight of stairs or walking across a room eventually turn into exhausting endeavors. This is because, over time, regardless of the underlying cause, heart damage typically progresses, owing to a constant barrage of oxidative stress and toxic lipids that alter heart cell energetics and, ultimately, the ability of the heart to function normally.
A team of researchers led by the University of California, Berkeley and the University of Michigan has discovered an antibody that blocks the spread within the body of the dengue virus, a mosquito-borne pathogen that infects between 50 and 100 million people a year. The virus causes what is known as dengue fever, symptoms of which include fever, vomiting and muscle aches, and can lead to more serious illnesses, and even death.
The fascinating compound eyes of insects consist of hundreds of individual eyes known as "facets". In the course of evolution, an enormous variety of eye sizes and shapes has emerged, often representing adaptations to different environmental conditions. Scientists, led by an Emmy Noether research group at the University of Göttingen, together with scientists from the Andalusian Centre for Developmental Biology (CABD) in Seville, have now shown that these differences can be caused by very different changes in the genome of fruit flies.
Egg cells are among the largest cells in the animal kingdom. If moved only by the random jostlings of water molecules, a protein could take hours or even days to drift from one side of a forming egg cell to the other. Luckily, nature has developed a faster way: cell-spanning whirlpools in the immature egg cells of animals such as mice, zebrafish and fruit flies. These vortices enable cross-cell commutes that take just a fraction of the time. But until now, scientists didn't know how these crucial flows formed.
(Boston)--What percent of patients with Alzheimer's Disease (AD) currently have severe dementia? Do more people have mild disease? Or are the majority suffering with moderate dementia? A new study using data from the Framingham Heart Study (FHS) sheds light on these trends.
In 2007, an increase in world food prices led to a global rush for land in the form of land grabs or large-scale land acquisitions. Over the last two decades, such acquisitions have resulted in millions of hectares of land changing hands in developing nations. Although such changeover can increase the cultivation of crops needed to feed the world's growing population and spark new agricultural practices and technologies, it can also lead to environmental degradation, increased carbon emissions and threats to the livelihoods of smallholder farmers.
Financial responsibility means managing money in a relatively sensible way by minimizing superfluous or unnecessary spending. But according to new research from the University of Notre Dame, people think they are more financially responsible than they actually are.
New probes allow scientists to see four-stranded DNA interacting with molecules inside living human cells, unravelling its role in cellular processes.
DNA usually forms the classic double helix shape of two strands wound around each other. While DNA can form some more exotic shapes in test tubes, few are seen in real living cells.
As marijuana outlets open after the drug is legalized, the density of those recreational retailers is associated with more use and a greater intensity of use among young adults, according to a new RAND Corporation study.
The study is among the first to examine associations between the density of marijuana outlets and marijuana use over time, and is the first to include unlicensed dispensaries in such an analysis.
Research led by the University of Wyoming shows that physical weathering is far more important than previously recognized in the breakdown of rock in mountain landscapes. Because it is difficult to measure, physical weathering has commonly been assumed to be negligible in previous studies.
A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord.
The discovery, published in the Journal of Neuroimmunology, could be important in treating or preventing the progression of multiple sclerosis and other central nervous system disorders. The new research in a mouse model advances earlier work to develop the compound - known as sobetirome - that has already showed promise in stimulating the repair of myelin.
With the impact of climate change increasing by the day, scientists are studying the ways in which human behavior contributes to the damage. A recent study at Walla Walla University, by a collaboration of researchers from Walla Walla University and La Sierra University, examined the effects of acidic water on octopuses, potentially bringing new insight into both how our activities impact the world around us, and the way that world is adapting in response.
The human organism requires a variety of small molecules, such as sugars or fats, in order to function properly. The composition of these so-called metabolites and their interaction - the metabolism - varies from person to person and is dependent not only on external influences, such as nutrition, but also to a significant extent on natural variations in our genetic make-up.