Culture
Irvine, Calif. -- An interdisciplinary team of biologists and mathematicians at the University of California, Irvine has developed a new tool to help decipher the language cells use to communicate with one another.
In a paper published today in Nature Communications, the researchers introduce CellChat, a computational platform that enables the decoding of signaling molecules that transmit information and commands between the cells that come together to form biological tissues and even entire organs.
Law enforcement and those in the military, rather than doctors and celebrities, are the most preferred messengers on firearm safety, a Rutgers study found.
The findings, published in the journal Preventive Medicine, can help communicate the importance of safe firearm storage and reduce the rate of suicides, Rutgers researchers say.
Researchers from California Polytechnic State University and University of Oregon published a new paper in the Journal of Marketing that examines the potential benefits for firms and consumers of pick-your-price (PYP) over pay-what-you-want (PWYW) and fixed pricing strategies.
The study, forthcoming in the Journal of Marketing, is titled "The Control-Effort Trade-Off in Participative Pricing: How Easing Pricing Decisions Enhances Purchase Outcomes" and is authored by Cindy Wang, Joshua Beck, and Hong Yuan.
[Vienna, Feb 18, 2021] Communities worldwide are trying to address inequality. One promising approach could be to look at the design of a city, according to research with real-world data in the journal Nature Communications.
An international team of scientists, including members of the Complexity Science Hub Vienna (CSH), show that urban planning directly influences the formation of social networks in a city and subsequently the socio-economic equality or inequality of its citizens.
An irregular sleep schedule can increase a person's risk of depression over the long term as much as getting fewer hours of sleep overall, or staying up late most nights, a new study suggests.
Even when it comes to just their mood the next day, people whose waking time varies from day to day may find themselves in as much of a foul mood as those who stayed up extra late the night before, or got up extra early that morning, the study shows.
The UK's first national lockdown from March 2020 and its immediate aftermath saw a massive shift in consumer habits that was initially mandated but then lingered as shops and restaurants opened but risks from the virus remained.
A new study from the universities of Cambridge and Newcastle used data from the ONS to compare retail, hospitality and online sales in the UK between March and August 2020 with average figures for the same months for the years 2010-2019.
A research team from the Institut national de la recherche scientifique (INRS) has improved the protective effect of a molecule against ischemic stroke, which is caused by an interruption of blood flow to the brain. The results of the study, conducted in collaboration with a Spanish team, were published in the Communications Biology of Nature Research journal.
PHOENIX, Ariz. and DUARTE, Calif. -- Feb. 17, 2021 -- Urinalysis has long been a staple of physical exams to detect and manage a number of diseases and disorders, but not cancer. What if it were that easy, though, and cancer was detected in its very earliest stages when the disease responds more favorably to treatment and improved outcomes are more likely?
Severe forms of malaria such as Plasmodium falciparum may be deadly even after treatment with current parasite-killing drugs. This is due to persistent cyto-adhesion of infected erythrocytes even though existing parasites within the red blood cells are dead. As vaccines for malaria have proved less than moderately effective, and to treat these severe cases of P. falciparum malaria, new avenues are urgently needed. Latest estimates indicate that more than 500 million cases of malaria and more than 400,000 deaths are reported worldwide each year.
Extending the symptoms that trigger a PCR test for COVID-19 could help detect around a third more cases of the disease.
New research led by researchers at King's College London and published in the Journal of Infection suggests that restricting testing to the 'classic triad' of cough, fever and loss of smell which is required for eligibility for a PCR test through the NHS may have missed cases. Extending the list to include fatigue, sore throat, headache and diarrhoea would have detected 96% of symptomatic cases.
Astronomers have tested a method for reconstructing the state of the early Universe by applying it to 4000 simulated universes using the ATERUI II supercomputer at the National Astronomical Observatory of Japan (NAOJ). They found that together with new observations the method can set better constraints on inflation, one of the most enigmatic events in the history of the Universe. The method can shorten the observation time required to distinguish between various inflation theories.
Circadian clocks, which regulate the metabolic functions of all living beings over a period of about 24 hours, are one of the most fundamental biological mechanisms. In humans, their disruption is the cause of many metabolic diseases such as diabetes or serious liver diseases. Although scientists have been studying this mechanism for many years, little is known about how it works.
CHAMPAIGN, Ill. -- Researchers who focus on fat know that some adipose tissue is more prone to inflammation-related comorbidities than others, but the reasons why are not well understood. Thanks to a new analytical technique, scientists are getting a clearer view of the microenvironments found within adipose tissue associated with obesity. This advance may illuminate why some adipose tissues are more prone to inflammation - leading to diseases like type 2 diabetes, cancer and cardiovascular disorders - and help direct future drug therapies to treat obesity.
Understanding the molecular biology of brain tumors is key to prognosis and treatment said Le Bonheur Neuroscience Institute Co-Director Frederick Boop, MD, in his presentation "How Molecular Biology Impacts Clinical Practice" at the International Society for Pediatric Neurosurgery (ISPN) 2020 Virtual Meeting.
"Historically we have depended on what we see under a microscope to differentiate tumor types and determine prognosis and therapy," said Boop. "We know now that what we see doesn't necessarily predict how these tumors are going to behave."
A new UBC Okanagan study finds children not only reap the benefits of working with therapy dogs-they enjoy it too.
"Dog lovers often have an assumption that canine-assisted interventions are going to be effective because other people are going to love dogs," says Nicole Harris, who conducted this research while a master's student in the School of Education. "While we do frequently see children improve in therapy dog programs, we didn't have data to support that they enjoyed the time as well."