This is a supplementary video to the Molecular Therapy publication "Prevention of Dystrophic Pathology in Severely Affected Dystrophin/Utrophin-deficient Mice by Morpholino-oligomer-mediated Exon-skipping" showing visual evidence of mouse with pronounced curving of the spine and dramatically reduced mobility as a result of deficiency of both dystrophin and utrophin proteins.
(Photo Credit: University of Oxford)