A drug being developed as a treatment for ovarian cancer has shown single agent activity with durable disease control in some patients in a Phase-II clinical trial, an international research group has reported.
Dr Ursula Matulonis from Dana-Farber Cancer Institute in the USA reported the results of the single-agent trial of the drug, called MLN8237, in a poster at the 35th Congress of the European Society for Medical Oncology (ESMO).
For patients with advanced lung cancer whose tumors carry EGFR activating mutations, first-line treatment with erlotinib nearly tripled progression-free survival compared to a standard chemotherapy combination, show results from the first prospective Phase-III study to report findings in this setting.
The new results from the OPTIMAL trial were reported at the 35th Congress of the European Society for Medical Oncology (ESMO) in Milan, Italy.
Educational policy is controversial: positions on achievement gaps, troubled schools and class size are emotionally charged, and research studies often come to very different conclusions.
But what if there was a new way of looking at the problem -- a way that treats education as a complex system (taking into account all interactions) and uses computer modeling and network analysis to provide a comprehensive look at the outcomes of policy choices?
ANN ARBOR, Mich. — A new study looking at how hospitals identify pediatric patients who develop catheter-associated bloodstream infections (CA-BSI) found significant inconsistencies in the methods used to report the number of patients who develop them.
New York, NY, October 8, 2010—Young adults continue to represent one of the largest groups of Americans without health insurance, with nearly 15 million people aged 19-29 uninsured in 2009—an increase of more than 1 million over 2008, according to a Commonwealth Fund report released today. However, the Affordable Care Act (ACA) is poised to make a significant difference for this population, as up to 12.1 million could gain subsidized insurance once all of the law's provisions go into effect in 2014.
Los Baños, Philippines – Environmental changes are to blame for a 15% drop in the yield of "miracle rice" – also known as rice variety IR8 – since the 1960s when it was first released and lauded for its superior yields that helped avert famine across Asia at the time.
IR8 used to produce 9.5 to 10.5 tons per hectare, significantly more than other varieties in the 1960s when average global rice yields were around only 2 tons per hectare. But, when grown today, IR8 can yield only around 7 tons per hectare.
HOUSTON, Oct. 8, 2010 – Direct-to-consumer (DTC) genetic tests available from retailers and the Internet let people learn about their genomes without going to a doctor, but they raise the question of who is responsible for oversight and regulation of these tests. Critics worry about safety risks if consumers base important lifestyle or medical decisions on inaccurate or misunderstood test results.
Many drug-resistant infections are the result of bacterial biofilms, structured aggregates of bacteria that live on surfaces and that are extremely resistant to environmental stresses. These biofilms impact human health in many ways — cystic fibrosis, for example, is a disease in which patients die from airway bacterial biofilm infections that are invulnerable to even the most potent antibiotics.
Young adults continue to represent one of the largest groups of Americans without health insurance, with nearly 15 million people aged 19-29 uninsured in 2009—an increase of more than 1 million over 2008, according to a Commonwealth Fund report released today. However, the Affordable Care Act (ACA) is poised to make a significant difference for this population, as up to 12.1 million could gain subsidized insurance once all of the law's provisions go into effect in 2014.
Washington, DC/Beijing, China (7-8 October 2010)—A new study released today in Washington, DC and Beijing suggests that one of the world's largest and "greenest" paper companies, in concert with local officials and other middlemen, used illegal means to gain control over thousands of hectares of Chinese forestlands, with a goal of acquiring 120 thousand hectares for a eucalyptus plantation in the Guangxi Autonomous Region of southern China.
Ultrasound can speed the healing of fractures. A randomized controlled trial reported in the open access journal BMC Musculoskeletal Disorders has found that the use of low-intensity pulsed ultrasound (LIPUS) in patients with tibial fractures which showed inadequate progress toward healing resulted in 34% greater bone mineral density (BMD) in the fracture area after 16 weeks than use of a sham device.
WASHINGTON—October 7, 2010—The U.S. invested $139 billion last year in health research from all public and private sources, according to Research!America's latest annual estimate. That amount represents only 5.6% of the $2.47 trillion overall U.S. health spending in 2009—or 5.6¢ of every health dollar—which varies no more than 0.2% from 2005 levels.
The estimate is available here: http://www.researchamerica.org/uploads/healthdollar09.pdf.
Transgenic corn's suppression of the European corn borer has saved Midwest farmers billions of dollars in the past decade, reports a new study in Science.
WASHINGTON, DC-In the weeks leading up to the 2010 midterm elections, five forecasters or teams of forecasters offer models and predictions for the House in the most recent issue (October 2010) of PS: Political Science and Politics, a journal of the American Political Science Association. The models offer a broad consensus that the Republicans will make substantial gains in the House, although there is not a consensus over how large those gains will be.
