Culture
A UCLA-led research team has identified a chemical cocktail that enables the production of large numbers of muscle stem cells, which can self-renew and give rise to all types of skeletal muscle cells.
The advance could lead to the development of stem cell-based therapies for muscle loss or damage due to injury, age or disease. The research was published in Nature Biomedical Engineering.
DALLAS, March 17, 2021 -- Stroke patients treated via a mobile stroke unit (MSU) received clot-busting medications faster and more often - and recovered significantly better than patients who receive regular emergency care by standard ambulance, according to late-breaking science presented today at the American Stroke Association's International Stroke Conference 2021. The virtual meeting is March 17-19, 2021 and is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health.
URBANA, Ill. - Opioid use has dramatically increased in the 21st century, especially among young adults. A new study from the University of Illinois provides insights on usage patterns among Illinois high school students to help inform prevention and treatment strategies.
Using molecular dating tools and epidemiological simulations, researchers at University of California San Diego School of Medicine, with colleagues at the University of Arizona and Illumina, Inc., estimate that the SARS-CoV-2 virus was likely circulating undetected for at most two months before the first human cases of COVID-19 were described in Wuhan, China in late-December 2019.
Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital (NRI) have identified and characterized two regions of DNA required for the proper expression of Mecp2/MECP2 in mice and humans.
These findings, published in Genes & Development, are helping to shed light on the function of these DNA regions and how they could be potential targets for diagnostic and therapeutic interventions for intellectual disabilities such as Rett Syndrome and MECP2 Duplication Syndrome.
During the first six months of the pandemic, as people attempted to stay away from hospitals caring for those sick with COVID-19, potentially avoidable hospitalizations for non-COVID-19-related conditions fell far more among white patients than Black patients, according to a new study that looked at admissions to UCLA Health hospitals.
LA JOLLA, CALIF. - March 19, 2021 - Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug candidate that blocks the uptake of glutamine, a key food source for many tumors, and slows the growth of melanoma. The drug is a small molecule that targets a glutamine transporter, SLC1A5, which pumps the nutrient into cancer cells--offering a promising new approach for treating melanoma and other cancers. The study was published in the journal Molecular Cancer Therapeutics.
Colorectal cancer survivors who maintained a stable body weight but lost muscle and developed fatty deposits in their muscles faced a 40 percent higher risk of premature death than patients who avoided both health issues.
The giraffe is a truly puzzling animal. With its exceptional anatomy and suite of evolutionary adaptations, the giraffe is an outstanding case of animal evolution and physiology. Now, an international team of researchers from the University of Copenhagen and Northwestern Polytechnical University in China have produced a high-quality genome from the giraffe and investigated which genes are likely to be responsible for its unique biological features.
Researchers have channeled the universe's earliest light - a relic of the universe's formation known as the cosmic microwave background (CMB) - to solve a missing-matter mystery and learn new things about galaxy formation. Their work could also help us to better understand dark energy and test Einstein's theory of general relativity by providing new details about the rate at which galaxies are moving toward us or away from us.
Many bacteria swim towards nutrients by rotating the helix-shaped flagella attached to their bodies. As they move, the cells can either 'run' in a straight line, or 'tumble' by varying the rotational directions of their flagella, causing their paths to randomly change course. Through a process named 'chemotaxis,' bacteria can decrease their rate of tumbling at higher concentrations of nutrients, while maintaining their swimming speeds. In more hospitable environments like the gut, this helps them to seek out nutrients more easily.
Water is an ephemeral thing. It can emerge from an isolated spring, as if by magic, to birth a babbling brook. It can also course through a mighty river, seeping into the soil until all that remains downstream is a shady arroyo, the nearby trees offering the only hint of where the water has gone.
(BOSTON) ¬-- Human cells typically transcribe half of their roughly 20,000 genes into RNA molecules at any given time. Just like with proteins, the function of those RNA species not only relies on their abundance but also their precise localization within the 3D space of each cell.
DALLAS - March 17, 2021 - UT Southwestern researchers have identified the structure of a key member of a family of proteins called nicotinic acetylcholine receptors in three different shapes. The work, published online today in Cell, could eventually lead to new pharmaceutical treatments for a large range of diseases or infections including schizophrenia, lung cancer, and even COVID-19.
Toronto, ON -A new study published in the journal Substance Use and Misuse has found that adverse childhood experiences, such as physical and sexual abuse and neglect, predict greater performance-enhancing substance use in young adults.