Culture

SILVER SPRING, Md. - As concern has grown over COVID-19 variants and their implications for how well COVID-19 vaccines will protect against the virus, researchers have proposed a method to examine instances of SARS-COV-2 infections in people who have received a COVID-19 vaccine.

Genomic sieve analysis of these so-called "breakthrough" SARS-CoV-2 infections in COVID vaccine trials is a critical tool to identify viral mutations associated with vaccine failure and to predict how vaccination impacts the virus' evolution.

Scientists at Sinai Health say they have discovered a new pathway that controls dangerous overreactions in a body's immune system, including deadly forms of hyper-inflammation.

In new findings out today in the journal Science, researchers at the Lunenfeld-Tanenbaum Research Institute (LTRI) detail how a protein known as WAVE2, a protein expressed in all immune cells, plays a critical role in maintaining immune system balance.

The evolving science of wisdom rests on the idea that wisdom's defined traits correspond to distinct regions of the brain, and that greater wisdom translates into greater happiness and life satisfaction while being less wise results in opposite, negative consequences.

An analysis of adult human brain tissue reveals over 900 proteins tied to epilepsy. The brain disorder, estimated to afflict more than 3 million Americans, is mostly known for symptoms of hallucinations, dreamlike states, and uncontrolled, often disabling bodily seizures.

Led by researchers at NYU Grossman School of Medicine, the study examined molecular differences among the brains of 14 epilepsy patients and another group of 14 adults of similar age and gender who did not have the disease.

Researchers from Charité - Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes. It is faster and cheaper than a conventional blood count. To demonstrate the technique's potential, the researchers used blood plasma collected from COVID-19 patients. Using the new technology, they identified eleven previously unknown proteins which are markers of disease severity. The work has been published in Nature Biotechnology*.

Tel-Aviv, ISRAEL - March 25, 2021 - Wild Biotech, a preclinical stage drug discovery & development company emerging out of stealth mode, today announces the publication of its first major paper, which appears in the journal Science. The study mapped the gut microbiota of animals in the wild on an unprecedented scale, adding millions of potentially novel microbiome-based therapeutics for human diseases to the company's already massive database. Wild will use these findings to first tap its database for targets in inflammatory, immune and gastrointestinal diseases.

Researchers at Baylor College of Medicine, Shandong University in China and other institutions may have found an explanation for dawn phenomenon, an abnormal increase of blood sugar only in the morning, observed in many patients with type 2 diabetes. They report in the journal Nature that mice lacking the circadian clock gene called Rev-erb in the brain show characteristics similar to those of dawn phenomenon.

WASHINGTON (March 25, 2021)--Although demand for COVID-19 vaccines currently seems high, vaccine hesitancy could pose a major threat to public health efforts to end the pandemic, according to an editorial published today in the journal Science.

Narcissism is driven by insecurity, and not an inflated sense of self, finds a new study by a team of psychology researchers. Its research, which offers a more detailed understanding of this long-examined phenomenon, may also explain what motivates the self-focused nature of social media activity.

CHAMPAIGN, Ill. -- Materials that contain special polymer molecules may someday be able to warn us when they are about to fail, researchers said. Engineers at the University of Illinois Urbana-Champaign have improved their previously developed force-sensitive molecules, called mechanophores, to produce reversible, rapid and vibrant color change when a force is applied.

Researchers at GMI - Gregor Mendel Institute of Molecular Plant Biology of the Austrian Academy of Sciences, the University of North Carolina at Chapel Hill and The Howard Hughes Medical Institute (HHMI) use two complementary approaches to unveil a co-evolutionary mechanism between bacteria and plants and also explain complex immune response patterns observed in the wild. Together the papers change the way scientists have been thinking about the relationship of a bacterial antigenic component with its plant immune receptor.

A pediatric heart transplant procedure pioneered by Canadian doctors--once deemed impossible--has been shown to be at least as effective as the traditional approach, according to newly published research in The Lancet Child & Adolescent Health.

How can we better understand how people move during the pandemic and how they spread COVID-19? New George Mason University's College of Health and Human Services research is one of the first individual-level studies to explore this question.

Opioids are the main driver of fatal drug overdoses in the United States, according to the Centers for Disease Control and Prevention, resulting in 46,802 deaths in 2018, usually because the person stops breathing.

Naloxone -- a Food and Drug Administration-approved medication used to reverse overdoses from opioids, such as heroin, morphine and oxycodone -- works by restoring normal respiration to a person whose breathing has slowed or stopped.

Skoltech scientists and their colleagues have proposed a new human height inheritance model that accounts for the interaction between various factors that influence adult human height. The research was published in the European Journal of Human Genetics.

Human height is a classical quantitative trait that depends on sex, genetics, and the environment.