Culture
ANN ARBOR--We are made of stardust, the saying goes, and a pair of studies including University of Michigan research finds that may be more true than we previously thought.
WEHI researchers have discovered a key differentiation process that provides an essential immune function in helping to control cancer and infectious diseases.
The research, published in Science Immunology, is the first to show a new factor - DC-SCRIPT - is required for the function a particular type of dendritic cell - called cDC1 - that is essential in controlling the immune response to infection.
Led by WEHI Professor Stephen Nutt, Dr Michael Chopin and Mr Shengbo Zhang, it defines the role for a new regulatory protein - DC-SCRIPT - in producing dendritic cells.
What The Study Did: This survey study examined the career development, productivity, childcare needs and likelihood of leaving the workforce among employees at an academic medical center during the COVID-19 pandemic.
Authors: Angela Fagerlin, Ph.D., of the University of Utah in Salt Lake City, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2021.3997)
Extended surges in the South and West in the summer and early winter of 2020 resulted in regional increases in excess death rates, both from COVID-19 and from other causes, a 50-state analysis of excess death trends has found. Virginia Commonwealth University researchers' latest study notes that Black Americans had the highest excess death rates per capita of any racial or ethnic group in 2020.
What The Study Did: This study updates an analysis of deaths in the United States in 2020, including deaths due to COVID-19 as well as all other causes.
Authors: Steven H. Woolf, M.D., M.P.H., of the Virginia Commonwealth University School of Medicine in Richmond, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2021.5199)
People who radicalize to extremist ideologies often are triggered by negative life events or exposure to propaganda, and those who escape from extreme groups frequently are aided by an individual or group that intervenes to help them reject the philosophy, according to a new RAND Corporation study.
ITHACA, NY, April 2, 2021 - A team of researchers from the Boyce Thompson Institute (BTI) has discovered a distinct group of bacteria that may help fungi and plants acquire soil nutrients. The findings could point the way to cost-effective and eco-friendly methods of enriching soil and improving crop yields, reducing farmers' reliance on conventional fertilizers.
Infectious diseases are a leading cause of global mortality. During an infection, bacteria experience many different stresses -- some from the host itself, some from co-colonizing microbes and others from therapies employed to treat the infection. In this arms race to outwit their competition, bacteria have evolved mechanisms to stay alive in the face of adversities. One such mechanism is the stringent response pathway. Understanding how the activation of the stringent response pathway is controlled can provide clues to treat infection.
James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has long studied neglected tropical diseases -- chronic and disabling parasitic infections that primarily affect poor and underserved communities in developing nations. They're called "neglected" because there is little financial incentive for pharmaceutical companies to develop therapies for them.
A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer's disease in a new study by investigators at the University of Chicago.
In a new study, researchers identify three clinical COVID-19 phenotypes, reflecting patient populations with different comorbidities, complications and clinical outcomes. The three phenotypes are described in a paper published this week in the open-access journal PLOS ONE 1st authors Elizabeth Lusczek and Nicholas Ingraham of University of Minnesota Medical School, US, and colleagues.
PHILADELPHIA - A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has identified nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases.
Within southeast Michigan's Middle Eastern and North African community, those who worry about deportation or believe they've been treated unfairly are likely to face more adverse conditions associated with poor health, including food insecurity and financial distress.
The MENA people who face several of these barriers are also more likely to report chronic illness and mental health issues as well as worse overall health.
Washington, April 2, 2021--The Organisation for Economic Co-operation and Development (OECD) will release a new PISA report on student growth mindset on Thursday, April 8 at 5:00 a.m. ET, followed by a press conference held in collaboration with the American Educational Research Association (AERA) and the Yidan Prize Foundation at 10:30 a.m. ET.
Waiting for your turn can be frustrating, especially when it comes to COVID-19 vaccinations. But prioritizing who receives the limited supply of vaccines available saves lives and reduces spread of infection, according to a study published today in the journal PNAS from the University of California, Davis.