The final results from an international clinical trial involving nearly 2,000 patients with Crohn's disease support the use of a new management strategy referred to as accelerated step-care as a best practice for the care of active Crohn's disease. The REACT (Randomized Evaluation of an Algorithm for Crohn's Treatment) study, led by Robarts Clinical Trials at Western University (London, Canada) provides valuable new insights for community gastroenterologists which should benefit patients.
Culture
Seeing is believing, but smellizing – a new term for prompting consumers to imagine the smell of a product – could be the next step toward more effective advertising.
Researchers came to this conclusion through four studies of products most of us would like to smellize: cookies and cake.
Professor of Marketing Maureen Morrin of Temple University's Fox School of Business co-authored Smellizing Cookies and Salivating: A Focus on Olfactory Imagery to examine the impact imagining what a food smells like would have on consumer behavior.
COLUMBIA, Mo. – Self-employment can allow older workers to stay in the labor market longer and earn additional income, yet little research has addressed if reasons for self-employment vary across gender and culture. Now, University of Missouri researchers have studied factors that contribute to self-employment and found these factors differ for men and women in the United States and New Zealand.
CHICAGO --- If you're 60 and older, every additional hour a day you spend sitting is linked to doubling the risk of being disabled -- regardless of how much moderate exercise you get, reports a new Northwestern Medicine® study.
The study is the first to show sedentary behavior is its own risk factor for disability, separate from lack of moderate vigorous physical activity. In fact, sedentary behavior is almost as strong a risk factor for disability as lack of moderate exercise.
Scientists from the Wildlife Conservation Society, the ARC Centre of Excellence for Coral Reef Studies, and other groups have found that the fishing villages of Madagascar—a country with little history of natural resource regulation—are generally supportive of fishing regulations, an encouraging finding that bodes well for sustainable strategies needed to reduce poverty in the island nation.
An entrepreneurial climate is more important than access to financing and banks in encouraging self-employment growth, according to rural economists.
"Because people who get laid off may end up working for themselves, self-employment can be a good news, bad news situation," said Stephan Goetz, professor of agricultural and regional economics, Penn State, and director of the Northeast Regional Center for Rural Development. "However, the self-employed do tend to support other nearby businesses and that can lead to employment growth and income growth across the county."
The results of a Journal of the American Medical Association study offer a glimmer of hope to families caring for a loved one with Alzheimer's disease. Researchers at the University of Rochester, Johns Hopkins University, and six other academic medical centers found that a high dose of a common antidepressant drug (citalopram) significantly reduced agitation in patients participating in the study. However, given potentially concerning side effects of citalopram, researchers say further investigation is needed to determine whether a smaller dose will be as effective.
The drug combination indacaterol/glycopyrronium (trade name: Ultibro Breezhaler, Xoterna Breezhaler) has been approved since September 2013 for adults with chronic obstructive pulmonary disease (COPD). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this drug combination offers an added benefit over the appropriate comparator therapy.
Afatinib (trade name: GIOTRIF) has been approved in Germany since September 2013 for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating EGF receptor mutations who have not been treated with an EGF receptor tyrosine-kinase inhibitor (EGFR TKI). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this new drug offers an added benefit over the appropriate comparator therapy.
Feb. 19, 2014 (Toronto) - An antidepressant medication has shown potential in treating symptoms of agitation that occur with Alzheimer's disease and in alleviating caregivers' stress, according to a multi-site U.S.- Canada study.
New research from psychologists at the universities of Kent and Limerick has found that music that is felt to be 'beautiful but sad' can help people feel better when they're feeling blue.
The research investigated the effects of what the researchers described as Self-Identified Sad Music (SISM) on people's moods, paying particular attention to their reasons for choosing a particular piece of music when they were experiencing sadness - and the effect it had on them.
Cancer cell spread to the sentinel node—the lymph node to which cancer cells are most likely to spread from a primary tumor—is a risk factor for melanoma death. According to a study published in this week's PLOS Medicine by Anja Ulmer, Christoph Klein and colleagues from the Universities of Tübingen and Regensburg, Germany, the prognosis of a patient largely depends on the number of disseminated cancer cells per million lymphocytes in the sentinel node. Even very low numbers were found to be predictive for reduced survival.
By combining a synthetic scaffolding material with gene delivery techniques, researchers at Duke University are getting closer to being able to generate replacement cartilage where it's needed in the body.
The antidepressant drug citalopram, sold under the brand names Celexa and Cipramil and also available as a generic medication, significantly relieved agitation in a group of patients with Alzheimer's disease. In lower doses than those tested, the drug might be safer than antipsychotic drugs currently used to treat the condition, according to results of a clinical trial led by Johns Hopkins researchers that included seven other academic medical centers in the United States and Canada.
Among patients who had completed standard rehabilitation after hip fracture, the use of a home exercise program that included exercises such as standing from a chair or climbing a step resulted in improved physical function, according to a study in the February 19 issue of JAMA.