Culture
CHAPEL HILL, NC - UNC School of Medicine scientists led a collaboration of researchers to demonstrate a potentially powerful new strategy for treating cystic fibrosis (CF) and potentially a wide range of other diseases. It involves small, nucleic acid molecules called oligonucleotides that can correct some of the gene defects that underlie CF but are not addressed by existing modulator therapies. The researchers used a new delivery method that overcomes traditional obstacles of getting oligonucleotides into lung cells.
Researchers at Karolinska Institutet in Sweden found industrial chemicals in the organs of fetuses conceived decades after many countries had banned the substances. In a study published in the journal Chemosphere, the researchers urge decision makers to consider the combined impact of the mix of chemicals that accumulate in people and nature.
As consumers and corporations alike become more environmentally conscious, the chemical industry is working to find solutions to the plastic waste crisis. One idea is to use biodegradable polymers known as polyhydroxyalkanoates (PHA) as replacements for traditional plastic packaging and other materials. A feature article in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, explores the possibilities and pitfalls of PHA.
Reston, VA--The effects of COVID-19 on the brain can be accurately measured with positron emission tomography (PET), according to research presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2021 Annual Meeting. In the study, newly diagnosed COVID-19 patients, who required inpatient treatment and underwent PET brain scans, were found to have deficits in neuronal function and accompanying cognitive impairment, and in some, this impairment continued six months after their diagnosis.
CHAMPAIGN, Ill. -- Health care workers often don't adopt new guidelines for best practices in medical care until well after those guidelines are established. A team of researchers led by Eunice E. Santos, the dean of the School of Information Sciences at the University of Illinois Urbana-Champaign, has developed a new computational modeling and simulation framework to analyze decision-making and identify effective dissemination strategies for medical guidelines.
An algorithm can predict when narwhals hunt - a task once nearly impossible to gain insight into. Mathematicians and computer scientists at the University of Copenhagen, together with marine biologists in Greenland, have made progress in gathering knowledge about this enigmatic Arctic whale at a time when climate change is pressuring them.
DURHAM, N.C. - Special diets, exercise programs, supplements and vitamins -- everywhere we look there is something supposed to help us live longer. Maybe those work: human average life expectancy has gone from a meager 40-ish years to a whopping 70-something since 1850. Does this mean we are slowing down death?
Osteoporosis researchers at the UVA School of Medicine have taken a new approach to understanding how our genes determine the strength of our bones, allowing them to identify several genes not previously known to influence bone density and, ultimately, our risk of fracture.
The work offers important insights into osteoporosis, a condition that affects 10 million Americans, and it provides scientists potential new targets in their battle against the brittle-bone disease.
Woods Hole, MA (June 16, 2021) -- Woods Hole Oceanographic Institution (WHOI) climate modeler Dr. Alan Condron and United States Geological Survey (USGS) research geologist Dr. Jenna Hill have found evidence that massive icebergs from roughly 31,000 years ago drifted more than 5000km (> 3,000 miles) along the eastern United States coast from Northeast Canada all the way to southern Florida. These findings were published today in Nature Communications.
Scientists at Weill Cornell Medicine have developed a computational technique that greatly increases the resolution of atomic force microscopy, a specialized type of microscope that "feels" the atoms at a surface. The method reveals atomic-level details on proteins and other biological structures under normal physiological conditions, opening a new window on cell biology, virology and other microscopic processes.
In a study, published June 16 in Nature, the investigators describe the new technique, which is based on a strategy used to improve resolution in light microscopy.
While crop yield has achieved a substantial boost from nanotechnology in recent years, alarms over the health risks posed by nanoparticles within fresh produce and grains have also increased. In particular, nanoparticles entering the soil through irrigation, fertilizers and other sources have raised concerns about whether plants absorb these minute particles enough to cause toxicity.
Although each organism has a unique genome, a single gene sequence, each individual has many epigenomes. An epigenome consists of chemical compounds and proteins that can bind to DNA and regulate gene action, either by activating or deactivating them or producing organ- or tissue-specific proteins. As it is a highly dynamic material, it can provide a large amount of information to shed light on the evolution of the various tissues and organs that make up the body.
Philadelphia, June 16, 2021 - The SARS-CoV-2 virus that causes COVID-19 may have the ability to reactivate dormant tuberculosis (TB). In a novel study scientists report in The American Journal of Pathology that infection with a specific coronavirus strain reactivated dormant Mycobacterium tuberculosis (MTB) in mice. This knowledge may help to develop new vaccines for COVID-19 and avoid a potential global tuberculosis epidemic.
The presence of pro-inflammatory cytokines in the blood can boost the effects of daily cannabis use and heighten the risk of developing psychosis in adulthood. Similar results have been observed, also in the presence of cytokines, when cannabis is used during adolescence. Psychotic disorders have symptoms such as delirium, loss of a sense of reality, hallucinations, hearing voices, and cognitive and social impairments.
NEW YORK, NY (June 16, 2021)--Spectacular images of a molecule that shuttles omega-3 fatty acids into the brain may open a doorway for delivering neurological therapeutics to the brain.