Culture

Sight is by far the sense that we humans use the most when navigating an environment. When those who are blind or visually impaired walk alone, they put themselves at great risk of falling or colliding with obstacles, especially when traversing new places. Unfortunately, the number of visually impaired people throughout the world is likely to increase in the near future because of the rapidly aging population. Thus, there is an urgent need for innovative and cost-effective solutions to help visually impaired people navigate safely.

When invaded by a virus, our body cells launch an alert to neighboring cells to increase their antiviral defenses to prevent the infection from spreading. Some viruses, however, manage to bypass this system by mimicking the host's RNA, preventing them from being detected by the infected cell and avoiding this alert. In the case of SARS-CoV-2, this mimicking uses a protein known as nsp14. This protein is also very important for virus multiplication, a task which is facilitated by its binding to the nsp10 protein, resulting in a protein complex.

A study of 49 patients reveals that toxins from the bacterial pathogen Staphylococcus aureus can destroy the body's blood-clotting platelets, raising the risk of death during bacterial blood infections. Further experiments in mice also showed that the approved drugs ticagrelor and oseltamivir protected platelets and helped treat infections, suggesting these compounds could be repurposed into badly needed therapies for blood infections. Bacterial blood infections have mortality rates as high as 20% to 30% even with supportive care, and these rates have remained high for decades.

Immunotherapy, which recruits the body's own immune system to attack cancer, has given many cancer patients a new avenue to treat the disease.

But many cancer immunotherapy treatments can be expensive, have devastating side effects, and only work in a fraction of patients.

Researchers at the Pritzker School of Molecular Engineering at the University of Chicago have developed a new therapeutic vaccine that uses a patient's own tumor cells to train their immune system to find and kill cancer.

News coverage of expert scientific evidence on vaccine safety is effective at increasing public acceptance of vaccines, but the positive effect is diminished when the expert message is juxtaposed with a personal narrative about real side effects, new research has found.

Scientists make pivotal discovery of method for wireless modulation of neurons with X-rays that could improve the lives of patients with brain disorders. The X-ray source only requires a machine like that found in a dentist’s office.

Many people worldwide suffer from movement-related brain disorders. Epilepsy accounts for more than 50 million; essential tremor, 40 million; and Parkinson’s disease, 10 million.

Researchers Mario Guarracino the HSE Laboratory of Algorithms and Technologies for Networks Analysis in Nizhny Novgorod and Julius ?ilinskas and Algirdas Lančinskas from Vilnius University, have proposed a new method of testing for COVID-19. This group method allows results to be obtained 13 times faster as compared to individual testing of each sample.

An old technique flexes its muscles

In the heart of black cherry's native range, including a part of the Allegheny Hardwoods that bills itself as the "Black Cherry Capital of the World," the tree's regeneration, growth and survival have all been declining for more than a decade. In a new analysis, a team of USDA Forest Service and University of Missouri scientists identify likely factors behind the tree's decline and, more significantly, conclude that black cherry may be the tip of the iceberg in terms of change in eastern deciduous forests.

URBANA, Ill. - Pumpkin growers dread the tiny tan scabs that form on their fruit, each lesion a telltale sign of bacterial spot disease. The specks don't just mar the fruit's flesh, they provide entry points for rot-inducing fungus and other pathogens that can destroy pumpkins and other cucurbits from the inside out. Either way, farmers pay the price, with marketable yields reduced by as much as 90%.

Cambridge, MA - Astronomers have now obtained a new view of the supermassive black hole at the center of galaxy M87. Images released today by the Event Horizon Telescope (EHT) collaboration reveal how the black hole, some 55 million light-years away, appears in polarized light.

The image marks the first time astronomers have captured and mapped polarization, a sign of magnetic fields, so close to the edge of a black hole.

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Philadelphia, March 25, 2021 - Anabolic androgenic steroids (AAS), a synthetic version of the male sex hormone testosterone, are sometimes used as a medical treatment for hormone imbalance. But the vast majority of AAS is used to enhance athletic performance or build muscle because when paired with strength training. AAS use increases muscle mass and strength, and its use is known to have many side effects, ranging from acne to heart problems to increased aggression.

Curtin University research has uncovered the first solid clues about the very beginning of the supercontinent cycle of Earth, finding it was kick-started two billion years ago.

Detailed in a paper published in Geology, a team of researchers from Curtin's Earth Dynamics Research Group found that plate tectonics operated differently before two billion years ago, and the 600 million years supercontinent cycle likely only started during the second half of Earth's life.

Deforestation, certain types of reforestation and commercial palm plantations correlate with increasing outbreaks of infectious disease, shows a new study in Frontiers in Veterinary Science. This study offers a first global look at how changes in forest cover potentially contribute to vector-borne diseases--such as those carried by mosquitos and ticks--as well as zoonotic diseases, like Covid-19, which jumped from an animal species into humans.