Culture

The latest findings show that with clever science, a single fingerprint left at a crime scene could be used to determine whether someone has touched or ingested class A drugs.

A pioneering new study led by UCL scientists has revealed, for the first time, a layer of genetic material involved in controlling the production of tau; a protein which plays a critical role in serious degenerative conditions, such as Parkinson's and Alzheimer's disease.

Research has found that strict lockdowns to reduce the spread of COVID-19 might be responsible for delaying normal cardiorespiratory development in children.

The study, the first to examine the topic, is published in the European Journal of Pediatrics. It was carried out by Dr Lee Smith of Anglia Ruskin University (ARU) and a team of academics from Spain, led by Dr Ruben Lopez-Bueno of the University of Zaragoza.

Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence. By installing such a point mutation in a specific gene, an international research team led by the University of Zurich has succeeded in sustainably lowering high LDL cholesterol levels in the blood of mice and macaques. This opens up the possibility of curing patients with inherited metabolic liver diseases.

World-leading eye experts have made a breakthrough that could potentially change the way cataracts are treated - with potential for drug therapy to replace surgery.

Cataract is a clouding of the eye lens that develops over time and affects the quality of vision. It is caused by an accumulation of protein in the lens that reduce the transmission of light to the retina. Previous research led by ARU found that cataracts account for almost half of global cases of blindness.

Wednesday 19 May 2021 - New research published today sheds important light on how the production of a key protein in the brain is controlled, which could pave the way for new treatments for a wide range of neurological conditions.

In a study part-funded by Parkinson's UK, researchers investigated a section of genetic material known as antisense long non-coding RNA (lncRNA), which helps fine-tune the production of the protein tau inside brain cells. This precision in tau regulation is crucial for smooth functioning of the nerve cells.

Brazil is the world leader in sweet orange production, but citrus cultivation in the region faces constant threats concerning the availability of water and the outbreak of diseases. New research published in the Journal of Applied Microbiology indicates that a fatty acid called hexanoic acid may help protect against one such problem: citrus canker, a bacterial infection that causes brownish eruptive lesions on the leaves, stems, and fruit of citrus trees.

NEW YORK, NY (May 19, 2021)--A new study from Columbia University and an international team of researchers identifies multiple ways to achieve the same health benefits from exercise--as long as the exercise "cocktail" includes plenty of light physical activity.

Computed tomography -- CT scanning -- which combines a series of X-ray images taken from different angles around an organism and uses computer processing to create cross-sectional images of its bones, is providing new insight into an old initiative to characterize fishes in Africa's Lake Malawi.

SARS-CoV-2 has evolved to acquire mutations on the spike protein--the part of the virus that protrudes from its surface and latches onto cells to infect them--that enhance the coronavirus' ability to bind to human cells or evade antibodies. A new study from the Centers for Genomics and Systems Biology at New York University and NYU Abu Dhabi uses computational modeling to assess the biological significance of spike protein mutations, uncovering versions of the virus that bind more tightly or resist antibodies and offering a promising public health surveillance tool.

Press release - ESE statement: COVID-19 and endocrine and metabolic diseases. An updated statement from the European Society of Endocrinology

New expert statement confirms strong links between our hormones and COVID-19

While the APP protein is well-known for its key role in Alzheimer's disease, its contribution to healthy brain function, by contrast, has remained largely unknown until now. Recently, an international research team, led by molecular biologist Prof. Dr Ulrike Müller from Heidelberg University, gained new insights on the physiological functions of the APP protein family by using a mouse model lacking APP. The absence of APP during brain development was shown to result in the malformation of important brain regions implicated in learning and memory.

Individuals are often prescribed increasing numbers of medications as they age, and while many of these prescriptions are justifiable, some may be inappropriate.

By the end of the first year of the pandemic in metropolitan Stockholm, investigators estimate that one-fifth of adults in the region previously had COVID-19. The findings, which are published in the Journal of Internal Medicine, come from analyses of anti-viral antibody responses in healthy blood donors and pregnant women.

Unbound nickel atoms and other heavy elements have been observed in very hot cosmic environments, including the atmospheres of ultra-hot exoplanets and evaporating comets that ventured too close to our Sun or other stars. A new study conducted by JU researchers reveals the presence of nickel atoms in the cold gasses surrounding the interstellar comet 2I/Borisov. The team's finding is being published in Nature on 19 May 2021.