Brain

BUFFALO, N.Y. — Obesity may alter the way we taste at the most fundamental level: by changing how our tongues react to different foods.

In a Nov. 13 study in the journal PLOS ONE, University at Buffalo biologists report that being severely overweight impaired the ability of mice to detect sweets.

Compared with slimmer counterparts, the plump mice had fewer taste cells that responded to sweet stimuli. What's more, the cells that did respond to sweetness reacted relatively weakly.

PITTSBURGH—From using concrete or abstract materials to giving immediate or delayed feedback, there are rampant debates over the best teaching strategies to use. But, in reality, improving education is not as simple as choosing one technique over another.

Carnegie Mellon University and Temple University researchers scoured the educational research landscape and found that because improved learning depends on many different factors, there are actually more than 205 trillion instructional options available.

Within the hospitality industry, manager support for fun is instrumental in reducing employee turnover, particularly for younger employees, according to a team of researchers. However, manager support for fun also reduces employee productivity, which can negatively impact sales performance.

WEST ORANGE, NJ November 21, 2013. Kessler Foundation researchers published the results of the MEMREHAB Trial in Neurology, the medical journal of the American Academy of Neurology, providing the first Class I evidence for the efficacy of cognitive rehabilitation in multiple sclerosis (MS). The article, Chiaravalloti N, Moore NB, Nikelshpur OM, DeLuca D: An RCT to treat learning impairment in MS. Neurology 2013(81), was released as an epub ahead of print on November 8. It was accompanied by an editorial: Filippi M, Rocca MA: Let's rehabilitate cognitive rehabilitation for MS.

CHAMPAIGN, Ill. — When reading text or listening to someone speak, we construct rich mental models that allow us to draw conclusions about other people, objects, actions, events, mental states and contexts. This ability to understand written or spoken language, called "discourse comprehension," is a hallmark of the human mind and central to everyday social life.

RIVERSIDE, Calif. — In 2008, the CEO of British Petroleum, Tony Hayward announced that BP's safety record was among the best in the industry. Under his leadership, BP ran operational safety training sessions for its employees and encouraged a culture of safety to satisfy its stakeholders, including employees, the community, and the environment.

In addition to being used as a recreational drug, marijuana has been used for centuries to treat a variety of conditions, from chronic pain to epilepsy. However, its medical value is greatly limited by debilitating side effects. A study published by Cell Press November 21st in the journal Cell has revealed the molecular pathways responsible for marijuana-induced learning and memory problems. The findings suggest that preventing these side effects could be as easy as taking an over-the-counter painkiller.

DURHAM, N.C. -- A genetic defect that profoundly affects speech in humans also disrupts the ability of songbirds to sing effective courtship tunes. This defect in a gene called FoxP2 renders the brain circuitry insensitive to feel-good chemicals that serve as a reward for speaking the correct syllable or hitting the right note, a recent study shows.

A team led by UC San Francisco scientists has identified the disruption of a single type of cell -- in a particular brain region and at a particular time in brain development -- as a significant factor in the emergence of autism.

The finding, reported in the November 21, 2013 issue of Cell, was made with techniques developed only within the last few years, and marks a turning point in autism spectrum disorders (ASDs) research.

Pity the poor autism researcher. Recent studies have linked hundreds of gene mutations scattered throughout the brain to increased autism risk. Where do you start?

UCLA neuroscientists may have an answer. They are the first to map groups of autism-risk genes by function, and to identify where and when these genes normally play major roles in early brain development.

A team of scientists has shown how the environment shapes learning and memory by training locusts like Pavlov's dog to associate different smells with reward or punishment.

Desert locusts are notorious for their devastating swarms. However, they do not always live in swarms — they switch between a lone living 'solitary phase' and a swarming 'gregarious' phase. The two phases differ profoundly in looks, behaviour and in their life style.

Finding major new clues to the origins of autism, a Yale-led team of researchers has pinpointed which cell types and regions of the developing human brain are affected by gene mutations linked to autism. They report their findings in the Nov. 21 issue of the journal Cell.

Analyzing massive amounts of gene expression data generated by the BrainSpan project, the team identified common neural circuits affected by autism-risk genes and when, where, and in what cell types those genes exert their effects on the developing human brain and lead to autism spectrum disorders.

Putnam Valley, NY. (Nov. 21 2013) – It is known that transplanting neural stem/progenitor cells (NS/PCs) into the spinal cord promotes functional recovery after spinal cord injury (SCI). However, which transplantation sites provide optimal benefit?

Using an approach combining in vivo recordings and optogenetic manipulations in mice, the researchers succeeded in showing that the inhibition of parvalbumin-expressing prefrontal interneurons triggers a chain reaction resulting in fear behaviour. Conversely, activation of these parvalbumin interneurons significantly reduces fear responses in rodents.

This research is published in the journal Nature

COLUMBIA, Mo. – Fish, unlike humans, can regenerate nerve connections and recover normal mobility following an injury to their spinal cord. Now, University of Missouri researchers have discovered how the sea lamprey, an eel-like fish, regrows the neurons that comprise the long nerve "highways" that link the brain to the spinal cord. Findings may guide future efforts to promote recovery in humans who have suffered spinal cord injuries.