Brain

Scientists have shown for the first time that a chemical in the brain called galanin is involved in the risk of developing depression.

And the research, undertaken by a European research team, points to a strong reason to develop drugs that modify galanin functioning as a new class of antidepressant drug.

Galanin is a neuropeptide (a small protein) that was discovered and investigated over 30 years ago by various groups including the Swedish scientist Tomas Hokfelt. He is one of the senior authors of the paper published in the journal PNAS.

The problems people with autism have with memory formation, higher-level thinking and social interactions may be partially attributable to the activity of receptors inside brain cells, researchers at Washington University School of Medicine in St. Louis have learned.

The study found a 'stop mechanism' that determined brain signals telling the individual to stop drinking water when no longer thirsty, and the brain effects of drinking more water than required.

Researcher Professor Derek Denton from the Faculty of Medicine, Dentistry and Health Sciences at the University of Melbourne said the study provided insight into the human instincts that determine survival behaviour and are also of medical importance. 


"The speed at which the goats completed the task at 10 months compared to how long it took them to learn indicates excellent long-term memory," said co-author Dr Elodie Briefer, now based at ETH Zurich.

Before each learning session, some of the goats had the opportunity to watch another goat to demonstrate the task.

Dr Briefer added: "We found that those without a demonstrator were just as fast at learning as those that had seen demonstrations. This shows that goats prefer to learn on their own rather than by watching others."

A study published in Diabetologia (the journal of the European Association for the Study of Diabetes) is the first to provide direct evidence that fetal brain response to a dose of sugar given orally to its mother is associated with the mother's insulin sensitivity. This may indicate that the risk of subsequent obesity and diabetes may be pre-programmed in the womb. The study is by Dr Hubert Preissl and Dr Andreas Fritsche, University of Tübingen, Germany and German Center for Diabetes Research (DZD), Neuherberg, Germany, and colleagues.

Knowing what another person wants is not a trivial issue, particularly when the other's desires are different from our own. The ability to disengage from our own desire to cater to someone else's wishes is thought to be a unique feature of human cognition.

PROVIDENCE, R.I. [Brown University] — In life, many tasks have a context that dictates the right actions, so when people learn to do something new, they'll often infer cues of context and rules. In a new study, Brown University brain scientists took advantage of that tendency to track the emergence of such rule structures in the frontal cortex — even when such structure was not necessary or even helpful to learn — and to predict from EEG readings how people would apply them to learn new tasks speedily.

The flight muscles moving inside flies have been filmed for the first time using a new 3D X-ray scanning technique.

3D movies of the muscles were created by a team from Oxford University, Imperial College London, and the Paul Scherrer Institute (PSI), using the PSI's Swiss Light Source, a powerful X-ray source. The movies offer a glimpse into the inner workings of one of nature's most complex mechanisms, the blowfly's flight motor, and could inspire new designs of micro air vehicle and other micromechanisms.

Researchers at the University of California, San Diego School of Medicine have discovered impaired neuronal activity in the parts of the brain associated with anticipatory functioning among occasional 18- to 24-year-old users of stimulant drugs, such as cocaine, amphetamines and prescription drugs such as Adderall.

The brain differences, detected using functional magnetic resonance imaging (fMRI), are believed to represent an internal hard wiring that may make some people more prone to drug addiction later in life.

TAMPA, Fla. (March 25, 2014) – Following ischemic stroke, the integrity of the blood-brain barrier (BBB), which prevents harmful substances such as inflammatory molecules from entering the brain, can be impaired in cerebral areas distant from initial ischemic insult. This disruptive condition, known as diaschisis, can lead to chronic post-stroke deficits, University of South Florida researchers report.

ANN ARBOR, Mich. — What makes a person bipolar, prone to manic highs and deep, depressed lows? Why does bipolar disorder run so strongly in families, even though no single gene is to blame? And why is it so hard to find new treatments for a condition that affects 200 million people worldwide?

New stem cell research published by scientists from the University of Michigan Medical School, and fueled by the Heinz C. Prechter Bipolar Research Fund, may help scientists find answers to these questions.

TORONTO, ON – A new study by University of Toronto researchers has found that kids' books featuring animals with human characteristics not only lead to less factual learning but also influence children's reasoning about animals.

Researchers also found that young readers are more likely to attribute human behaviors and emotions to animals when exposed to books with anthropomorphized animals than books depicting animals realistically.

CAMBRIDGE, MA -- Doctors commonly use magnetic resonance imaging (MRI) to diagnose tumors, damage from stroke, and many other medical conditions. Neuroscientists also rely on it as a research tool for identifying parts of the brain that carry out different cognitive functions.

WASHINGTON - A large proportion of teenage boys and college men report having been coerced into sex or sexual behavior, according to research published by the American Psychological Association.

A total of 43 percent of high school boys and young college men reported they had an unwanted sexual experience and of those, 95 percent said a female acquaintance was the aggressor, according to a study published online in the APA journal Psychology of Men and Masculinity.

The study, published in the journal Technovation and written by Pere Ortín Ángel and Ferran Vendrell Herrero, covers financial data from two comparison samples of companies founded between 1994 and 2005. One sample is made up of 104 university spin-offs and the other is made up of 73 technology-based, non-university companies. The study compares what is known as the total factor productivity of these two samples. According to the study, in the university spin-offs this productivity is, on average, lower in the year in which the company is founded.