People diagnosed with Huntington's disease, most in their mid-thirties and forties, face a devastating prognosis: complete mental, physical, and behavioral decline within two decades. "Mutant" protein clusters, long blamed for the progression of the genetic disease, have been the primary focus of therapies in development by pharmaceutical companies. But according to new research from Prof. Gerardo Lederkremer and Dr. Julia Leitman of Tel Aviv University's Department of Cell Research and Immunology, in collaboration with Prof.
Brain
Johns Hopkins scientists report that rats exposed to high-energy particles, simulating conditions astronauts would face on a long-term deep space mission, show lapses in attention and slower reaction times, even when the radiation exposure is in extremely low dose ranges.
BUFFALO, N.Y. – A novel compound that targets an important brain receptor has a dramatic effect against a host of cocaine addiction behaviors, including relapse behavior, a University at Buffalo animal study has found.
The research provides strong evidence that this may be a novel lead compound for treating cocaine addiction, for which no effective medications exist.
The UB research was published as an online preview article in Neuropsychopharmacology last week.
Putnam Valley, NY. (Apr. 23 2014) – A team of researchers in Korea who transplanted human neural stem cells (hNSCs) into the brains of nonhuman primates and assessed cell survival and differentiation after 22 and 24 months found that the hNSCs had differentiated into neurons at 24 months and did not cause tumors.
Putnam Valley, NY. (Apr. 23, 2014) – People who have had a stroke, often suffer motor deficits with little potential to restore neurological function.
The trope that the likelihood of an accurate group decision increases with the abundance of brains involved might not hold up when a collective faces a variety of factors — as often happens in life and nature. Instead, Princeton University researchers report that smaller groups actually tend to make more accurate decisions while larger assemblies may become excessively focused on only certain pieces of information.
PITTSBURGH—The ability of individuals to store and instantly access thousands of their photos online has become a commonplace luxury, but the sheer size of these archives can be intimidating. Researchers at Carnegie Mellon University and Microsoft Research Cambridge, UK, have found people might actually enjoy their collections more by giving up a bit of control and learning to wait.
A new computer program could help doctors predict which patients might suffer potentially fatal side-effects from a key stroke treatment.
The program, which assesses brain scans using pattern recognition software similar to that used in airport security and passport control, has been developed by researchers at Imperial College London. Results of a pilot study funded by the Wellcome Trust, which used the software are published in the journal Neuroimage Clinical.
COLLEGE PARK, Md. – A study of older adults at increased risk for Alzheimer's disease shows that moderate physical activity may protect brain health and stave off shrinkage of the hippocampus– the brain region responsible for memory and spatial orientation that is attacked first in Alzheimer's disease. Dr. J.
In addition to its lipid-lowering effect, statins exert anti-inflammatory and antioxidant effects as well. Statins also provide protection against renal, pulmonary and myocardial ischemia/reperfusion injury. However, little evidence is available on similar changes in cerebral ischemia/reperfusion injury. Therefore, Dr. Qiuyun Tu and colleagues from Third Xiangya Hospital of Central South University in China verified that atorvastatin, a commonly used lipid-lowering drug, protects against cerebral ischemia/reperfusion injury through anti-infammatory and antioxidant effects.
Methylphenidate, also known as Ritalin, may prevent the depletion of self-control, according to research published in Psychological Science, a journal of the Association for Psychological Science.
Self-control can be difficult — sticking with a diet or trying to focus attention on a boring textbook are hard things to do. Considerable research suggests one potential explanation for this difficulty: Exerting self-control for a long period seems to "deplete" our ability to exert self-control effectively on subsequent tasks.
Previous studies have shown that proliferation of endogenous neural precursor cells cannot alone compensate for the damage to neurons and axons. From the perspective of neural plasticity, Dr. Yun Xiang and co-workers from Sun Yat-sen University in China observed the effects of functional electrical stimulation treatment on endogenous neural precursor cell proliferation and expression of basic fibroblast growth factor and epidermal growth factor in the rat brain on the infarct side.
This news release is available in Spanish.
Both acupuncture at Waiguan (SJ5) and sham acupuncture can activate/deactivate several brain regions in patients with ischemic stroke, but there are some difference in Brodmann areas 4, 6, 8, Brodmann areas 7, 39, 40, Brodmann areas 18, 19, 22 and Brodmann areas 13, 24, 32, 28. Most studies addressing the specificity of meridians and acupuncture points have focused mainly on the different neural effects of acupuncture at different points in healthy individuals. Dr.
Alzheimer's disease is the first cause of dementia and affects some 400,000 people in Spain alone. However, no effective cure has yet been found. One of the reasons for this is the lack of knowledge on the cellular mechanisms which cause alterations in nerve transmissions and the loss of memory in the initial stages of the disease.