Neurovance, Inc. today announced complete results from its phase 2a pilot study of EB-1020 SR, a non-stimulant, in adult male patients with all subtypes of ADHD (attention deficit hyperactivity disorder). EB-1020 SR is a norepinephrine- and dopamine-preferring triple reuptake inhibitor. The data showed a statistically significant improvement in ADHD symptoms on the ADHD-Rating Scale-IV (ADHD-RS-IV), the primary outcome measure, in a range similar to that reported in previously published trials with stimulants. EB-1020 SR appears to be well tolerated at the doses studied.
Brain
A new cultural psychology study has found that psychological differences between the people of northern and southern China mirror the differences between community-oriented East Asia and the more individualistic Western world – and the differences seem to have come about because southern China has grown rice for thousands of years, whereas the north has grown wheat.
WASHINGTON - Primary care teams that include both psychologists and physicians would help address known barriers to improved primary health care, including missed diagnoses, a lack of attention to behavioral factors and limited patient access to needed care, according to health care experts writing in a special issue of American Psychologist, the flagship journal of the American Psychological Association.
A variant of the gene KLOTHO is known for its anti-aging effects in people fortunate enough to carry one copy. Now researchers find that it also has benefits when it comes to brain function. The variant appears to lend beneficial cognitive effects by increasing overall levels of klotho in the bloodstream and brain.
A scientific team led by the Gladstone Institutes and UC San Francisco has discovered that a common form of a gene already associated with long life also improves learning and memory, a finding that could have implications for treating age-related diseases like Alzheimer's.
A newly identified difference between the brains of women and men with multiple sclerosis (MS) may help explain why so many more women than men get the disease, researchers at Washington University School of Medicine in St. Louis report.
In recent years, the diagnosis of MS has increased more rapidly among women, who get the disorder nearly four times more than men. The reasons are unclear, but the new study is the first to associate a sex difference in the brain with MS.
The findings appear May 8 in The Journal of Clinical Investigation.
EUGENE, Ore. -- When tracking a moving object, the two halves of the human brain operate much like runners successfully passing a baton during a relay race, says a University of Oregon researcher.
In a study online ahead of print in Current Biology, electroencephalogram (EEG) measured brainwaves from healthy young adults revealed how information about an attended object -- one being watched closely -- moves from one brain hemisphere to the other.
New research suggests that certain types of brain cells may be "picky eaters," seeming to prefer one specific energy source over others. The finding has implications for understanding the cognitive decline seen in aging and degenerative diseases such as Alzheimer's and multiple sclerosis.
ANN ARBOR, Mich. — A smartphone app that monitors subtle qualities of a person's voice during everyday phone conversations shows promise for detecting early signs of mood changes in people with bipolar disorder, a University of Michigan team reports.
While the app still needs much testing before widespread use, early results from a small group of patients show its potential to monitor moods while protecting privacy.
CHICAGO --- Adults with an autism spectrum disorder, who may have trouble talking about themselves and interacting socially, don't always make good impressions in job interviews and have low employment rates.
A new human simulation training program -- based on software originally used to train FBI agents -- helps adults with autism improve their job interview skills and confidence, reports a new Northwestern Medicine® study.
Research by the University of Liverpool has found that brief musical training can increase the blood flow in the left hemisphere of our brain. This suggests that the areas responsible for music and language share common brain pathways.
Researchers from the University's Institute of Psychology, Health and Society carried out two separate studies which looked at brain activity patterns in musicians and non-musicians.
Leesburg, VA, May 7, 2014—A study conducted at Massachusetts General Hospital and Harvard Medical School found that estimated radiation doses are substantially lower for pediatric CT exams of the brain that used an adaptive statistical iterative reconstruction technique (ASIR) compared to those that did not use ASIR. The researchers found that the brain and salivary gland doses were much lower for ASIR-enabled exams compared to those without ASIR technique.
Leesburg, VA, May 5, 2014—Glutamate imaging reveals ischemic lesions in the first 3 hours after stroke that are not distinguishable in T1-weighted and T2-weighted imaging.
Researchers using chemical exchange saturation transfer (CEST), an emerging MRI technology, have found that using glutamate with CEST shows high spatial resolution in vivo. The finding has the potential to speed diagnosis—and, therefore, treatment—in the critical first hours after a stroke.
A University of Alberta study is helping crack the code to happiness by exploring the long reach of depression and anger over more than two decades.
The study, published recently in the Journal of Family Psychology, followed 341 people for 25 years, and found that negative emotions they may have suffered as young adults can have a lasting grip on their couple relationships, well into middle age.
TALLAHASSEE, Fla. — Perceived age and weight discrimination, more than perceived race and sex discrimination, are linked to worse health in older adults, according to new research from the Florida State University College of Medicine.
The findings are part of a study measuring changes in health over a four-year period and published in the American Journal of Geriatric Psychiatry.