Despite great advances in understanding how the human brain works, psychiatric conditions, neurodegenerative disorders, and brain injuries are on the rise. Progress in the development of new diagnostic and treatment approaches appears to have stalled. In a special issue of the Cell Press journal Neuron, experts look at the challenges associated with "translational neuroscience," or efforts to bring advances in the lab to the patients who need them.
Brain
New Danish-led research suggests that signs of brain aging can be postponed in mice if placed on a high-fat diet. In the long term, this opens the possibility of treatment of children suffering from premature aging and patients with Alzheimer's and Parkinson's disease. The research project is headed by the Center for Healthy Aging, University of Copenhagen and the National Institute of Health.
Researchers at the Cognition and Brain Plasticity group of the Bellvitge Biomedical Research Institute (IDIBELL) and the University of Barcelona have been tracking the traces of implicit and explicit memories of fear in human. The study has been published in the journal Neurobiology of Learning and Memory and describes how in a context of fear, our brain differently encodes contextual memory of a negative event (the place, what we saw...) and emotional response associated.
A child's ability to distinguish musical rhythm is related to his or her capacity for understanding grammar, according to a recent study from a researcher at the Vanderbilt Kennedy Center.
Reyna Gordon, Ph.D., a research fellow in the Department of Otolaryngology and at the Vanderbilt Kennedy Center, is the lead author of the study that was published online recently in the journal Developmental Science. She notes that the study is the first of its kind to show an association between musical rhythm and grammar.
VTT Technical Research Centre of Finland has developed an innovative magnetometer that can replace conventional technology in applications such as neuroimaging, mineral exploration and molecular diagnostics. Its manufacturing costs are between 70 and 80 per cent lower than those of traditional technology, and the device is not as sensitive to external magnetic fields as its predecessors. The design of the magnetometer also makes it easier to integrate into measuring systems.
Researchers using a new type of tracking device on female elephant seals have discovered that adding body fat helps the seals dive more efficiently by changing their buoyancy.
A University of Oregon researcher wants those "R" words to resonate among young athletes. They are key terms used in an online educational tool designed to teach coaches, educators, teens and parents about concussions.
Brain 101: The Concussion Playbook successfully increased knowledge and attitudes related to brain injuries among students and parents in a study that compared its use in 12 high schools with the usual care practices of 13 other high schools during the fall 2011 sports season. The findings are online ahead of print in the Journal of Adolescent Health.
A study led by a researcher from Plymouth University in the UK, has discovered that the inhibition of a particular mitochondrial fission protein could hold the key to potential treatment for Parkinson's Disease (PD).
The findings of the research are published today, 5th November 2014, in Nature Communications.
PD is a progressive neurological condition that affects movement. At present there is no cure and little understanding of why some people get the condition. In the UK one on 500 people, around 127,000, have PD.
SCIENTISTS have found a pattern of genetic 'switches' – chemical marks that turn genes on or off - that are linked to breast cancer's spread to the brain, according to research* presented at the National Cancer Research Institute Cancer Conference in Liverpool today (Wednesday).
The researchers, based at the University of Wolverhampton, studied 24 breast cancers that had spread to the brain, along with samples from the original breast tumour, and found a handful of genes with faulty switches.
For years, scientists have debated how best to assess brain levels of oxytocin, a hormone implicated in social behaviors. Now, researchers at the Stanford University School of Medicine have found the first direct evidence in children that blood oxytocin measurements are tightly linked to levels of oxytocin in cerebrospinal fluid, which bathes the brain.
Low oxytocin levels in blood and CSF are both correlated to high anxiety levels, the research also showed. The findings will be published online Nov. 4 in Molecular Psychiatry.
Everyone knows the scene: a basketball player at the free throw line, bouncing the ball as he concentrates on the basket. It's a tight game, and his team needs this point. He regularly makes baskets from much farther away while avoiding defenders, but now, when all is calm, he chokes and misses the basket, and his team loses. Recent research from The Johns Hopkins University suggests that in situations like this, performance depends on two factors: the framing of the incentive in terms of a loss or a gain, and a person's aversion to loss.
San Diego — A recently developed Adeno-Associated Virus (AAV)-based medication has the potential to offer substantial protective effects for patients attempting to cease methamphetamine use. This research is being presented at the 2014 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in San Diego, Nov. 2-6.
Washington D.C., November 4, 2014 – A Clinical Perspectives article published in the November 2014 issue of the Journal of the American Academy of Child and Adolescent Psychiatry proposes a tool to empower stakeholders, guide caregivers, and provide a rationale for advocates, when considering the systems of support offered to people with an autism spectrum disorder (ASD).
Disturbances in the early stages of brain growth, such as preterm birth – when many of the brain's structures have not yet fully developed – appears to affect the brain's neuro-circuitry, which may explain premature babies' higher risk of neurodevelopmental disorders including ADHD and autism spectrum disorder.
CORAL GABLES, Fla. (November 4, 2014) — Think about the way our bodies are assembled during early development and ask: How do neighboring cells know that they are supposed to become a nerve or a bone cell and how do these tissues find the correct place and alignment? Researchers at the University of Miami (UM) are answering these crucial questions.