Through research in mice, scientists have found that proteins at the blood-brain barrier pump out riluzole, the only FDA-approved drug for ALS, or Lou Gehrig's disease, limiting the drug's effectiveness. However, when the investigators blocked these proteins, the effectiveness of riluzole increased and the animals experienced improved muscle function, slower disease progression, and prolonged survival.
Brain
December 1, 2014 -- A study just released by Columbia University's Mailman School of Public Health compared the use of prescription opioids and stimulants among high school graduates, non-graduates, and their college-attending peers, and found that young adults who do not attend college are at particularly high risk for nonmedical prescription opioid use and disorder. In contrast, the nonmedical use of prescription stimulants is higher among college-educated young adults. Results of the study are published online in the journal Social Psychiatry and Psychiatric Epidemiology.
This news release is available in German.
Traumatic events leave their mark. People exposed to a traumatic experience early in life are more likely to be affected by illnesses such as borderline personality disorder or depression. However such experience can also have positive effects in certain circumstances. Thus, moderate stress in childhood may help a person develop strategies to better cope with stress in adulthood.
If we believe a negative trait we possess is linked to a related positive characteristic, we will be more productive in that domain, New York University researchers have found. Their study, which appears in the Journal of Experimental Social Psychology, establishes a novel "silver lining theory": negative attributes can produce positive results.
"I can't get the memories out of my mind!... I am right back in Vietnam, in the middle of the monsoon season at my guard post. My hands are freezing, yet sweat pours from my entire body...I smell a damp sulfur smell. Suddenly I see what's left of my buddy Troy, his head on a bamboo platter, sent back to our camp by the Viet Cong."i
December 1, 2014 - A study using intricate fiber dissection techniques provides new insights into the deep anatomy of the human brainstem--and helps to define "safe entry zones" for neurosurgeons performing brainstem surgery, according to a special article published in Operative Neurosurgery, a quarterly supplement to Neurosurgery, official journal of the Congress of Neurological Surgeons.
Philadelphia, PA, December 1, 2014 - Panic disorder is a severe form of anxiety in which the affected individual feels an abrupt onset of fear, often accompanied by profound physical symptoms of discomfort. Scientists have known from studying twins that genes contribute to the risk of panic disorder, but very little is known about which specific genes are involved.
PROVIDENCE, R.I. [Brown University] -- Lacrosse players swing hard, which is why errant stick blows are the leading cause of concussion in girls' and women's lacrosse. In a new study, researchers measured how much the worst blows accelerate the head and how much different kinds of headgear could reduce those accelerations.
Replenishing the supply of a molecule that normally activates cannabinoid receptors in the brain could relieve mood and anxiety disorders and enable some people to quit using marijuana, a Vanderbilt University study suggests.
Cannabinoid receptors are normally activated by compounds in the brain called endocannabinoids, the most abundant of which is 2-AG. They also are "turned on" by the active ingredient in marijuana.
A DRUG that could reduce the harmful side-effects of 'binge drinking', especially by teenagers, has been successfully developed and tested by a team of European scientists, including the University of Huddersfield's Professor Mike Page and Dr Karl Hemming. There is also the potential for new ways to treat Alzheimer's and other neurological diseases that damage the brain.
CHICAGO - Hybrid imaging with positron emission tomography and computed tomography (PET/CT) in the pituitary region of the brain is a promising tool for differentiating military veterans with post-traumatic stress disorder (PTSD) from those with mild traumatic brain injury (MTBI), according to a new study presented at the annual meeting of the Radiological Society of North America (RSNA).
The findings also lend support to the theory that many veterans diagnosed with PTSD may actually have hormonal irregularities due to pituitary gland damage from blast injury.
CHICAGO - Changes in brain connections visible on MRI could represent an imaging biomarker of Alzheimer's disease, according to a new study presented today at the annual meeting of the Radiological Society of North America (RSNA).
CHICAGO - Some high school football players exhibit measurable brain changes after a single season of play even in the absence of concussion, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).
PITTSBURGH--The rise of social media has seemed like a bonanza for behavioral scientists, who have eagerly tapped the social nets to quickly and cheaply gather huge amounts of data about what people are thinking and doing. But computer scientists at Carnegie Mellon University and McGill University warn that those massive datasets may be misleading.