Brain

INDIANAPOLIS – Protecting patient privacy has been recognized as the duty of health-care providers for about as long as doctors have seen patients. In 1996 that duty became a legal obligation when Congress passed the Health Insurance Portability and Accountability Act.

Scientists at The Wistar Institute and their colleagues have identified, for the first time, a molecule that can regulate microRNAs – short strands of RNA that play a vital role in gene expression and are closely associated with cancer. The discovery points the way to the development of a new generation of cancer drugs.

BETHLEHEM, PA (September 25, 2008)—A pair of recent studies suggest that e-mail is the most deceptive form of communications in the workplace–even more so than more traditional kinds of written communications, like pen-and-paper.

More surprising is that people actually feel justified when lying using e-mail, the studies show.

Massachusetts General Hospital (MGH) researchers are investigating a new approach to gene therapy for brain tumors – delivering a cancer-fighting gene to normal brain tissue around the tumor to keep it from spreading. An animal study published in the journal Molecular Therapy, the first to test the feasibility of such an approach, found that inducing mouse brain cells to secrete human interferon-beta suppressed and eliminated growth of human glioblastoma cells implanted nearby.

Zurich, Switzerland – September 24, 2008 – Love a rap artist's music, and you may develop fond feelings for the products placed in that artist's rap video. That is essentially the conclusion that a team of investigators came to in an intriguing research article published in this month's issue of Psychology & Marketing (P&M).

Eight-year-old children have a radically different learning strategy from twelve-year-olds and adults. Eight-year-olds learn primarily from positive feedback ('Well done!'), whereas negative feedback ('Got it wrong this time') scarcely causes any alarm bells to ring. Twelve-year-olds are better able to process negative feedback, and use it to learn from their mistakes. Adults do the same, but more efficiently.

Brain areas for cognitive control

RICHLAND, Wash. -- A single fluorescent molecule flashing as it gains or loses its electron has made the microscopic spotlight. Watching a whole gaggle of these molecules, they appear to work synchronously; but a new close-up view reveals mavericks that shine when they seemingly shouldn't. The work sets the stage for a better understanding of the underlying principles of certain reactions common to biofuel production.

Research led by Dr. David Spence of Robarts Research Institute at The University of Western Ontario shows that with more intensive medical therapy, the risk of stroke has become so low that at least 95 per cent of patients with asymptomatic carotid stenosis (ACS) would be better off with medical therapy than with surgery or stenting. ACS is a narrowing in the carotid artery, which supplies blood to the brain, which has not yet resulted in a stroke or transient ischemic attack (TIA).

HILTON HEAD, SC–The coordination of two systems are key for any horse to walk, trot, gallop or win a race. The first are the lower limbs, which allow the animal to move along on a "spring-like" tendon. The second is a complicated respiratory system, which allows a horse to take in one breadth for every stride they make while racing. For more than a decade a team of researchers has been working to unlock the secrets of equines. Their findings may provide a springboard for better muscular horse health, and a different approach to breathing devices for humans.

American children are approximately three times more likely to be prescribed psychotropic medication than children in Europe. A new study published today in BioMed Central's open access journal Child and Adolescent Psychiatry and Mental Health claims that the differences may be accounted for by regulatory practices and cultural beliefs about the role of medication in emotional and behavioural problems.

Researchers have long known that children who grow up in an aggressive or violent household are more likely to become violent or aggressive in future relationships. What has not been so clear is the developmental link between witnessing aggressive behavior as a child and carrying it out as an adult. What changes occur in a child that affect whether he or she will choose to deal with conflict in aggressive or violent ways?

Although school has been back for less than a month, it is likely that many children are already experiencing frustration and confusion in math class. Research at The University of Western Ontario in London, Canada could change the way we view math difficulties and how we assist children who face those problems.

Neuroscientists at Children's Hospital Boston have identified the first known "master switch" in brain cells to orchestrate the formation and maintenance of inhibitory synapses, essential for proper brain function. The factor, called Npas4, regulates more than 200 genes that act in various ways to calm down over-excited cells, restoring a balance that is thought to go askew in some neurologic disorders. The findings appear in the September 24 advance online edition of the journal Nature.

A physician's personality can affect practice behavior in inquiries about patient mood symptoms and the diagnosis of depression, according to a study led by University of Rochester Medical Center researchers.

HOUSTON – (Sept. 24, 2008) – Self-guided treatment for depression could soon be only a mouse click away.

Scientists with the National Space Biomedical Research Institute (NSBRI) are developing an interactive, multi-media program that will assist astronauts in recognizing and effectively managing depression and other psychosocial problems, which can pose a substantial threat to crew safety and mission operations during long-duration spaceflights.