Brain

An atomic-resolution view of an enzyme found only in the eye has given researchers at the University of Washington (UW) clues about how this enzyme, essential to vision, is activated. The enzyme, phosphodiesterase 6 (PDE6), is central to the way light entering the retina is converted into a cascade of signals to the brain.

This week undergraduate and graduate students in an advanced computer security course at Rice University in Houston are learning hands-on just how easy it is to wreak havoc on computer software used in today's voting machines.

As part of his advanced computer science class, Rice University Associate Professor and Director of Rice's Computer Security Lab Dan Wallach tests his students in a unique real-life experiment: They are instructed to do their very best to rig a voting machine in the classroom.

Here's how the experiment works:

The current system of publishing medical and scientific research provides "a distorted view of the reality of scientific data that are generated in the laboratory and clinic," says a team of researchers in this week's PLoS Medicine.

In their Essay, Neal Young (National Institutes of Health, USA), John Ioannidis (Tufts University School of Medicine, USA and University of Ioannina School of Medicine, Greece), and Omar Al-Ubaydli (George Mason University, USA) apply principles from the field of economics to present evidence consistent with a distortion.

Howard Hughes Medical Institute researchers have developed a new prenatal blood test that accurately detected Down syndrome and two other serious chromosomal defects in a small study of 18 pregnant women. If confirmed in larger trials, they say, the test would offer a safer and faster alternative to invasive prenatal tests such as amniocentesis that pose a small risk of miscarriage.

ST. PAUL, Minn. – Cerebral microbleeds, which are small bleeds within the brain, appear to be more common in African-Americans than in Caucasians, increasing the likelihood of having a stroke, according to a study published in the October 7, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology. These types of brain lesions can be an important indicator for stroke.

Washington, DC − Small, clinically silent areas of bleeding in the brain appear to be more common in black versus white stroke patients hospitalized for new brain bleeds, say researchers at Georgetown University Medical Center. These findings may help explain the higher risk of hemorrhagic stroke among the black population, especially in those who are medically underserved.