CD4+ T lymphocytes, or simply CD4 T cells, are the "brains" of the immune system, coordinating its activity when the body comes under attack. They are also the cells that are attacked by HIV, the devastating virus that causes AIDS and has infected roughly 40 million people worldwide. The virus slowly eats away at CD4 T cells, weakening the immune system.
EDITOR'S PICK: How cigarette smoke negatively impacts the consequences of viral infections
Jack Elias and colleagues, at Yale University School of Medicine, have performed new studies in mice that provide mechanistic insight into why viral infections have more severe consequences in individuals exposed to cigarette smoke than in those not exposed to cigarette smoke (e.g., influenza-infected smokers have increased mortality when compared with influenza-infected nonsmokers).
MADISON - We've all heard it. Many of us in fact believe it. Girls just aren't as good at math as boys.
But is it true? After sifting through mountains of data - including SAT results and math scores from 7 million students who were tested in accordance with the No Child Left Behind Act - a team of scientists says the answer is no. Whether they looked at average performance, the scores of the most gifted children or students' ability to solve complex math problems, girls measured up to boys.
Jülich scientists have succeeded in precisely measuring atomic spacings down to a few picometres using new methods in ultrahigh-resolution electron microscopy. This makes it possible to find out decisive parameters determining the physical properties of materials directly on an atomic level in a microscope. Knut Urban from Forschungszentrum Jülich, a member of the Helmholtz Association, reports on this in the latest issue (25 July) of the scientific high-impact journal Science.
An international research collaboration including research teams from the Children's Hospital in Boston (USA), King's College London and the Peninsula Medical School, has identified a gene that, when mutated, causes Duane syndrome.
The research is published in the latest edition of Science.
Irvine, Calif., July 24, 2008 — Adult stem cells originate in a different part of the brain than is commonly believed, and with proper stimulation they can produce new brain cells to replace those lost to disease or injury, a study by UC Irvine scientists has shown.
Two new research studies have discovered a long sought molecular link between our metabolism and components of the internal clock that drives circadian rhythms, keeping us to a roughly 24-hour schedule. The findings appear in the July 25th issue of the journal Cell, a publication of Cell Press.
The missing link is a well–studied mammalian protein called SIRT1, which was previously known to be switched on and off in accordance with cells' metabolic state and is perhaps best known for its potential life-extending properties.
GAINESVILLE, Fla. — If worms could talk, they might tell potential suitors, "I like the way you wriggle," complete with that telltale come slither look. But worms send their valentines via signals known as pheromones, a complex chemical code researchers are now cracking, according to a study published Wednesday (July 23) in the journal Nature.
CINCINNATI—A new approach to internal medicine residency training could improve patient care and physician-patient relationships, according to a University of Cincinnati (UC) study.
Eric Warm, MD, associate professor of medicine and lead investigator of the study, says research showed residents who spent increased time in outpatient settings as opposed to the hospital delivered a higher quality of care and had more satisfaction in their duties.
Results of this study are published in the July edition of the Journal of General Internal Medicine.
Although state lotteries, on average, return just 53 cents for every dollar spent on a ticket, people continue to pour money into them — especially low-income people, who spend a larger percentage of their incomes on lottery tickets than do the wealthier segments of society. A new Carnegie Mellon University study sheds light on the reasons why low-income lottery players eagerly invest in a product that provides poor returns.
Kidneys donated after individuals die from cardiovascular causes may be one of the best options for black patients in need of transplants, according to a study appearing in the October 2008 issue of the Journal of the American Society Nephrology (JASN). The research reveals that utilization of these organs should be expanded in order to reduce racial disparities that exist in renal transplantation.
From understanding climate change to predicting infectious disease outbreaks to engineering solutions to address disability, scientific research is increasingly crossing the boundaries between disciplines.
Researchers at the National Institute of Standards and Technology (NIST) and three collaborating institutions are using a new laboratory model of the membrane surrounding neurons in the brain to study how a protein long suspected of a role in early-stage Alzheimer’s disease actually impairs a neuron’s structure and function. The team’s findings are reported in a new paper in the Biophysical Journal.*
WEST LAFAYETTE, Ind. - Researchers have overcome a major obstacle in producing transistors from networks of carbon nanotubes, a technology that could make it possible to print circuits on plastic sheets for applications including flexible displays and an electronic skin to cover an entire aircraft to monitor crack formation.
The so-called "nanonet" technology - circuits made of numerous carbon nanotubes randomly overlapping in a fishnet-like structure - has been plagued by a critical flaw: The network is contaminated with metallic nanotubes that cause short circuits.
DURHAM, N.C. – Male fruit flies missing a gene for one particular odor receptor become clueless in matters of love, scientists at Duke University Medical Center have discovered.
Because they lack the ability to read important chemical cues, these flies will indiscriminately attempt to have sex with other males, and with females who have already mated. The signals they're missing are pheromones wafting from mated females and male flies. The work appears online in Nature Neuroscience.