Brain

BETHESDA, Md. (Dec. 11, 2008) − A vigorous 60-minute workout on a treadmill affects the release of two key appetite hormones, ghrelin and peptide YY, while 90 minutes of weight lifting affects the level of only ghrelin, according to a new study. Taken together, the research shows that aerobic exercise is better at suppressing appetite than non-aerobic exercise and provides a possible explanation for how that happens.

ST. PAUL, Minn. – With more and more people having brain MRIs for various reasons, doctors are finding people whose scans show signs of multiple sclerosis (MS) even though they have no symptoms of the disease. A new study published in the December 10, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology, found that a third of these people developed MS within an average of about five years.

A total of 13 new technologies in computer graphics and interactive techniques, including 3D graphics and animation, intuitive human-computer interaction technologies and neural signal processing, will be introduced by Singapore's A*STAR (Agency for Science, Technology and Research) at Asia's version of the world's largest and most prestigious computer graphics show, SIGGRAPH (Special Interest Group on GRAPHics and Interactive Techniques).

GAINESVILLE, Fla. — University of Florida researchers may have discovered why some brain cells necessary for healthy memory can survive old age or disease, while similar cells hardly a hairsbreadth away die.

The discovery, published online ahead of print in the Nature publication Cell Death & Differentiation, could help scientists understand and find solutions for age-related memory loss.

CHESTNUT HILL, MA -- Students from Asian countries were top performers in math and science at both the fourth and eighth grade levels, according to the most recent reports of the Trends in International Mathematics and Science Study (TIMSS), released by the study's directors Michael O. Martin and Ina V.S. Mullis of Boston College.

SAN FRANCISCO, CA – Dec 10, 2008 – Scientists from the Gladstone Institute of Neurological Disease (GIND), UCSF, and Stanford have discovered that a certain type of collagen, collagen VI, protects brain cells against amyloid-beta (Aβ ) proteins, which are widely thought to cause Alzheimer's disease (AD). While the functions of collagens in cartilage and muscle are well established, before this study it was unknown that collagen VI is made by neurons in the brain and that it can fulfill important neuroprotective functions.

Dr. Francois Bolduc keeps more than 300,000 fruit flies in a basement laboratory, where he manipulates their genes and then tests their mental abilities. He's called the "fly guy," and he may sound like a comic book villain, but Bolduc is no mad scientist.

Researchers at New York University's Center for Neural Science and the Baylor College of Medicine have identified a protein that when removed from mice results in behaviors that are akin to those with autism and obsessive-compulsive disorders. Their findings, which appear in the latest issue of the journal Neuron, may enhance our understanding of these and other neurological disorders.

A new study reveals that humans use different neural mechanisms for determining criminal responsibility and assigning an appropriate punishment. The research, published by Cell Press in the December 11th issue of the journal Neuron, provides fascinating insight into brain systems that may explain how thousands of years of reliance on human sanctions to enforce social norms gave rise to our current criminal justice system.

A new study reveals a link between dysregulation of a common signaling pathway and repetitive behaviors similar to those associated with multiple neurological and neurodegenerative disorders including, autism spectrum disorders, obsessive compulsive disorder, schizophrenia, and Huntington's disease. The research, published by Cell Press in the December 11th issue of the journal Neuron, identifies a critical role for a molecule linked to immunosuppression in learning, memory, and repetitive behavior and may lead to the development of new treatments for perseverative behaviors.

Reducing the activity of a gene called FKBP12 in the brains of mice affected neuron-to-neuron communication (synapse) and increased both fearful memory and obsessive behavior, indicating the gene could provide a target for drugs to treat diseases such as autism spectrum disorder, obsessive-compulsive disease and others, said researchers from Baylor College of Medicine in Houston in a report in the current issue of the journal Neuron.

Tampa, Fla. (Dec. 10, 2008) – Successfully monitoring the distribution and fate of transplanted stem cells through imaging and subsequent tracking would aid clinicians in their ability to evaluate the efficacy of transplanted cells. Three studies published in the current issue of Cell Transplantation (Vol. 17, No.8) assess various imaging techniques and evaluate the degree to which the techniques afford clinicians useable imaging and tracking data.

Bioluminescent imaging of human fetal hepatocytes

Tampa, Fla. (Dec. 10, 2008) – A study published in the current issue of CELL TRANSPLANTATION (Vol.17, No. 8) suggests that mature adipocytes - fat cells - could become a source for cell replacement therapy to treat central nervous system disorders.

EAST LANSING, Mich. --- Research by a Michigan State University chemist could eventually lead to a quicker and easier way of developing protein-based drugs that are key to treating a number of diseases, including cancer, diabetes and hepatitis.

Piscataway, N.J. – December 9, 2008 – A new study in Psychology of Women Quarterly finds that women who present themselves as confident and ambitious in job interviews are viewed as highly competent but also lacking social skills. Women who present themselves as modest and cooperative, while well liked, are perceived as low on competence. By contrast, confident and ambitious male candidates are viewed as both competent and likable and therefore are more likely to be hired as a manager than either confident or modest women.